Reviewed, UniProtKB/Swiss-Prot Q9A777 (CALB_CAUCR)

Names and origin

Protein names

Recommended name:
    Probable coniferyl aldehyde dehydrogenase
      Short name=CALDH
    EC=1.2.1.68

Gene names

Name:	calB
Ordered Locus Names:	CC_1849

Organism

Caulobacter crescentus (Caulobacter vibrioides) [Complete proteome] [HAMAP]

Taxonomic identifier

155892 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	485 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H.
Sequence similarities	Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular aldehyde metabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aldehyde dehydrogenase [NAD(P)+] activity Inferred from electronic annotation. Source: InterPro coniferyl-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 485	485	Probable coniferyl aldehyde dehydrogenase		PRO_0000056586
Sites
	Active site	226	1	By similarity
	Active site	260	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9A777-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 8222ABB2DC5E78C1	FASTA	485	52,721
	10 20 30 40 50 60 MNAPVNLSSD AHKAVMNDVL QRQKAAHLRD GPPSAEKRIQ WLNRCIDLLV GHQAEIAKAV 70 80 90 100 110 120 NQDFGSRSPE ATSLTDVAGS IGPLKHAREH LTKWMKPEKH KTTPAILGLF GAKATVQWQP 130 140 150 160 170 180 KGVVGVISPW NFPVNLTFAP LAGVFAAGNR AMIKPSEFTP ATSDLLKAMF AKAFNEEEVA 190 200 210 220 230 240 VFVGGPEVGQ AFSGLAFDHL VFTGATSVAK HVMRAAAENL VPVTLELGGK SPVILSRGAD 250 260 270 280 290 300 MATAAARVMN GKTLNAGQIC LAPDYVLAPQ EDVEAFVKEA QAAVSRYFPT IKDNPDYTAV 310 320 330 340 350 360 VAQRHYDRVK GYVDDARAKG ARVIEINPAG EDLSQQEHRK IPPTLILDPT DDMKVMQEEI 370 380 390 400 410 420 FGPVLPVKGY KTVDEAVDYV NAHDRPLALY WFGTDEAEKD RVLERTTSGG VTVNDVIFHV 430 440 450 460 470 480 AQENLPFGGI GPAGMGAYHG YDGFREFSHR KAVFQQLKKD IAPMLGLRPP YGEGIRKYLA GQIKK

References

[1]

"Complete genome sequence of Caulobacter crescentus." Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J. , Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001) [PubMed: 11259647] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19089 / CB15.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE005673 Genomic DNA. Translation: AAK23824.1.
PIR	D87478.
RefSeq	NP_420656.1.
3D structure databases
HSSP	HSSP built from PDB template 1AD3 based on UniProtKB P11883.
ModBase	Search...
Genome annotation databases
GeneID	942308.
GenomeReviews	Gene locus CC_1849 in contig AE005673_GR.
KEGG	ccr:CC_1849.
NMPDR	fig|190650.1.peg.1836.
TIGR	CC_1849.
Phylogenomic databases
HOGENOM	Q9A777.
OMA	HPPYGTF.
Enzyme and pathway databases
BRENDA	1.2.1.68. 2191.
Family and domain databases
InterPro	IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH. IPR012394. Aldehyde_DH_NAD(P). [Graphical view]
Gene3D	G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHER	PTHR11699. Aldehyde_dehyd. 1 hit. PTHR11699:SF15. ALDH. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
PIRSF	PIRSF036492. ALDH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. False negative. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CALB_CAUCR

Accession

Primary (citable) accession number: Q9A777

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 11, 2002
Last sequence update:	June 1, 2001
Last modified:	November 3, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)