Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptide chain release factor 2

Gene

prfB

Organism
Caulobacter crescentus (strain ATCC 19089 / CB15)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciCAULO:CC1874-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 2UniRule annotation
Short name:
RF-2UniRule annotation
Gene namesi
Name:prfBUniRule annotation
Ordered Locus Names:CC_1874
OrganismiCaulobacter crescentus (strain ATCC 19089 / CB15)
Taxonomic identifieri190650 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
Proteomesi
  • UP000001816 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001668101 – 371Peptide chain release factor 2Add BLAST371

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei247N5-methylglutamineUniRule annotation1

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF2.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

STRINGi190650.CC_1874.

Structurei

3D structure databases

ProteinModelPortaliQ9A752.
SMRiQ9A752.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CG1. Bacteria.
COG1186. LUCA.
HOGENOMiHOG000074814.
KOiK02836.
OMAiRLYEHEM.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00094. Rel_fac_2. 1 hit.
InterProiIPR014720. dsRBD_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR020853. Peptide_chain_release_fac2_bac.
IPR004374. PrfB.
[Graphical view]
PANTHERiPTHR11075:SF6. PTHR11075:SF6. 1 hit.
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00020. prfB. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9A752-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRPLRPTSS SPWDCSGGVF DWDVALRKLD ELNARVEDPT LWDRPSEAQA
60 70 80 90 100
VSRERANLAA KVEAVQSIER DLKDALEYAE LAEMESDEDS LNDARAQLKS
110 120 130 140 150
LKERAGRAEL EALLSGEADG NDCYVEINSG AGGTESCDWA GILLRMYTRW
160 170 180 190 200
ANAHGMTTEL IEETDGDQAG IKSATLLVKG ANAYGWLKTE AGVHRLVRIS
210 220 230 240 250
PYDSSARRHT SFASAWVYPV VDDNIEIEIN PSDVRTDTYR ASGAGGQHIN
260 270 280 290 300
KTDSAVRLTH IPTGIAVACQ AGRSQHQNRE EAWKMLRARL YEAELQKREA
310 320 330 340 350
AQQALEDQKT DIGWGHQIRS YVLQPYQMVK DLRTNVETSD TQGVLDGDLD
360 370
AFMAASLAQR VGHTRDGGEA S
Length:371
Mass (Da):40,922
Last modified:June 1, 2001 - v1
Checksum:iF66090AC5D3FEB44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK23849.1.
PIRiE87481.
RefSeqiNP_420681.1. NC_002696.2.
WP_010919740.1. NC_002696.2.

Genome annotation databases

EnsemblBacteriaiAAK23849; AAK23849; CC_1874.
GeneIDi942350.
KEGGiccr:CC_1874.
PATRICi21300752. VBICauCre124313_1891.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA. Translation: AAK23849.1.
PIRiE87481.
RefSeqiNP_420681.1. NC_002696.2.
WP_010919740.1. NC_002696.2.

3D structure databases

ProteinModelPortaliQ9A752.
SMRiQ9A752.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190650.CC_1874.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK23849; AAK23849; CC_1874.
GeneIDi942350.
KEGGiccr:CC_1874.
PATRICi21300752. VBICauCre124313_1891.

Phylogenomic databases

eggNOGiENOG4105CG1. Bacteria.
COG1186. LUCA.
HOGENOMiHOG000074814.
KOiK02836.
OMAiRLYEHEM.

Enzyme and pathway databases

BioCyciCAULO:CC1874-MONOMER.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00094. Rel_fac_2. 1 hit.
InterProiIPR014720. dsRBD_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR020853. Peptide_chain_release_fac2_bac.
IPR004374. PrfB.
[Graphical view]
PANTHERiPTHR11075:SF6. PTHR11075:SF6. 1 hit.
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00020. prfB. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRF2_CAUCR
AccessioniPrimary (citable) accession number: Q9A752
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.