Q9A717 (Q9A717_CAUCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL AAK23884.1

Gene names

Ordered Locus Names:

CC_1909

Organism

Caulobacter crescentus (Caulobacter vibrioides)

Taxonomic identifier

155892 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9A717 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 642C51EF8C91A77B	FASTA	398	42,576
	10 20 30 40 50 60 MTINRDKPLK VMLVAAEASG DALGAGLAKA LRARLGQGVT FVGIGGAKMA EQGVQSPFDI 70 80 90 100 110 120 AQLSILGILE SLKAYPRAMA RLKDTVALAA REKPDVAVLI DSWGFNIRLA HALRRLDPTL 130 140 150 160 170 180 PLVKYVAPQV WAYREGRAQA LAKAVDLLLS IQPMDKAYFD AAGLQNVFVG NSALAKRFDH 190 200 210 220 230 240 ADPGRLRAAI GAAASQQILL VLPGSRPSEI ERVMPAFEDA VRRLKVERPD LHIVVPAAYT 250 260 270 280 290 300 VAEAVKARVA GWPFRAHVIE DEGLKDDAFL AGDVALACSG TVTTELALAG RPMVVGYKTG 310 320 330 340 350 360 AVTYAIVKRL MKPRWITLFN IAAGKAVAPE LIQHACEGEG LAREVALRLD DPDLRQRQTA 370 380 390 EQYAALDRMG RGMPDPSEAA AEALLDFLSA RGALGRAG

References

[1]

"Complete genome sequence of Caulobacter crescentus." Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J. , Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001) [PubMed: 11259647] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19089 / CB15.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005673 Genomic DNA. Translation: AAK23884.1.
PIR	H87485.
RefSeq	NP_420716.1. NC_002696.2.
3D structure databases
ProteinModelPortal	Q9A717.
ModBase	Search...
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	942564.
GenomeReviews	Gene locus CC_1909 in contig AE005673_GR.
KEGG	ccr:CC_1909.
NMPDR	fig|190650.1.peg.1896.
PATRIC	21300822. VBICauCre124313_1926.
TIGR	CC_1909.
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK890663.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9A717_CAUCR

Accession

Primary (citable) accession number: Q9A717

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)