Q9A6N3 (GLK_CAUCR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucokinase
EC=2.7.1.2

Alternative name(s):
Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	CC_2054

Organism

Caulobacter crescentus (strain ATCC 19089 / CB15) [Reference proteome] [HAMAP]

Taxonomic identifier

190650 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter › Caulobacter crescentus

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00524.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	Glucokinase HAMAP-Rule MF_00524		PRO_0000215123
Regions
	Nucleotide binding	13 – 18	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9A6N3 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: BCDBDD25EE9549AC	FASTA	331	34,714
	10 20 30 40 50 60 MDGNHSGGLG LVGDIGGTNA RFALVEFDGQ DPRLIEPTAY RGEDYGTAED AIEEYLRKVG 70 80 90 100 110 120 VKHPDQAVVA VAGPIDHGQV HMTNLDWRIS EDGLRRAGGF RNAKLINDFT AQALAAPRVG 130 140 150 160 170 180 PKDLRQIGEL PTSGEGDLAI LGPGTGFGVA GLVRRHGQEI PLATEGGHVA FAPVDDVEIE 190 200 210 220 230 240 VLRALTRRLD GGRVSVERIL SGPGMEDLHV DLAAAEGRGV EALTAKQITE RAVEGCADSL 250 260 270 280 290 300 ATVNRFCAIL GSTAGDIALT LGARGGVFIA GGIAPRIIDI LEKSPFRERF DSKGRLSGFT 310 320 330 RSIPTHVILH PHTALIGAAV ALTPEGRAAV S

References

[1]

"Complete genome sequence of Caulobacter crescentus." Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J. , Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19089 / CB15.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005673 Genomic DNA. Translation: AAK24027.1.
PIR	G87503.
RefSeq	NP_420859.1. NC_002696.2.
3D structure databases
ProteinModelPortal	Q9A6N3.
SMR	Q9A6N3. Positions 10-322.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK24027; AAK24027; CC_2054.
GeneID	942977.
KEGG	ccr:CC_2054.
PATRIC	21301124. VBICauCre124313_2073.
Phylogenomic databases
eggNOG	COG0837.
HOGENOM	HOG000274469.
KO	K00845.
OMA	EAVIRHY.
ProtClustDB	CLSK890751.
Family and domain databases
HAMAP	MF_00524. Glucokinase.
InterPro	IPR003836. Glucokinase. [Graphical view]
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_CAUCR

Accession

Primary (citable) accession number: Q9A6N3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	June 1, 2001
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program