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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage).
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glucose-6-phosphate 1-dehydrogenase (zwf)
  2. 6-phosphogluconolactonase (pgl)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciCAULO:CC2056-MONOMER
UniPathwayiUPA00115; UER00409

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Ordered Locus Names:CC_2056
OrganismiCaulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus)
Taxonomic identifieri190650 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
Proteomesi
  • UP000001816 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000900901 – 2326-phosphogluconolactonaseAdd BLAST232

Interactioni

Protein-protein interaction databases

STRINGi190650.CC_2056

Structurei

3D structure databases

ProteinModelPortaliQ9A6N1
SMRiQ9A6N1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108Q79 Bacteria
COG0363 LUCA
HOGENOMiHOG000256284
KOiK01057
OMAiKQPHLAI

Family and domain databases

CDDicd01400 6PGL, 1 hit
InterProiView protein in InterPro
IPR005900 6-phosphogluconolactonase_DevB
IPR006148 Glc/Gal-6P_isomerase
IPR037171 NagB/RpiA_transferase-like
PfamiView protein in Pfam
PF01182 Glucosamine_iso, 1 hit
SUPFAMiSSF100950 SSF100950, 1 hit
TIGRFAMsiTIGR01198 pgl, 1 hit

Sequencei

Sequence statusi: Complete.

Q9A6N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFTPIKLEA FGSREDLYDA AASVLVGALT TAVARHGRVG FAATGGTTPA
60 70 80 90 100
PVYDRMATMT APWDKVTVTL TDERFVPATD ASSNEGLVRR HLLVGEAAKA
110 120 130 140 150
SFAPLFFDGV SHDESARKAE AGVNAATPFG VVLLGVGPDG HFASLFPGNP
160 170 180 190 200
MLDQGLDLAT DRSVLAVPPS DPAPDLPRLS LTLAALTRTD LIVLLVTGAA
210 220 230
KKALLDGDVD PALPVAAILK QDRAKVRILW AE
Length:232
Mass (Da):24,234
Last modified:June 1, 2001 - v1
Checksum:i8FBEA52F720F87B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005673 Genomic DNA Translation: AAK24029.1
PIRiA87504
RefSeqiNP_420861.1, NC_002696.2
WP_010919919.1, NC_002696.2

Genome annotation databases

EnsemblBacteriaiAAK24029; AAK24029; CC_2056
GeneIDi942979
KEGGiccr:CC_2056
PATRICifig|190650.5.peg.2075

Similar proteinsi

Entry informationi

Entry namei6PGL_CAUVC
AccessioniPrimary (citable) accession number: Q9A6N1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2001
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health