Reviewed, UniProtKB/Swiss-Prot Q9A3D5 (SUHB_CAUCR)

Names and origin

Protein names

Recommended name:
    Inositol-1-monophosphatase
      Short name=IMPase
      Short name=Inositol-1-phosphatase
      Short name=I-1-Pase
    EC=3.1.3.25

Gene names

Name:	suhB
Ordered Locus Names:	CC_3269

Organism

Caulobacter crescentus (Caulobacter vibrioides) [Complete proteome] [HAMAP]

Taxonomic identifier

155892 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Myo-inositol phosphate + H2O = myo-inositol + phosphate.
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the inositol monophosphatase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	inositol-1(or 4)-monophosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 256	256	Inositol-1-monophosphatase		PRO_0000142558
Regions
	Region	79 – 82	4	Substrate binding By similarity
Sites
	Metal binding	60	1	Magnesium 1 By similarity
	Metal binding	77	1	Magnesium 1 By similarity
	Metal binding	77	1	Magnesium 2 By similarity
	Metal binding	79	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	80	1	Magnesium 2 By similarity
	Metal binding	207	1	Magnesium 2 By similarity
	Binding site	60	1	Substrate By similarity
	Binding site	178	1	Substrate By similarity
	Binding site	207	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9A3D5-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 9E8C9B52AC96A81C	FASTA	256	27,927
	10 20 30 40 50 60 MIEAARKAAR GLARDFGEVT ELQVSKKGAA DFVTNADIKA EQTLFELLTK ARPGYGFLGE 70 80 90 100 110 120 ERGMVEGTDK THTWIVDPLD GTTNFMHAIP HFAVNIALQR EGEGIVAGVT YNPITNDLFW 130 140 150 160 170 180 VEKGKGAFLG AEKRLRVAAR RHLDEAILAT GVPFAGKPGH GQFLKELHQV SQKVAGVRRF 190 200 210 220 230 240 GAASLDLAWV AAGRFDAFWE RNLNSWDVAA GVLMIQESGG KITTIDESDH DVVQGKSILA 250 SNQDLHPQIL ERLRAA

References

[1]

"Complete genome sequence of Caulobacter crescentus." Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J. , Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001) [PubMed: 11259647] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19089 / CB15.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE005673 Genomic DNA. Translation: AAK25231.1.
PIR	C87654.
RefSeq	NP_422063.1.
3D structure databases
HSSP	HSSP built from PDB template 2HHM based on UniProtKB P29218.
ModBase	Search...
Genome annotation databases
GeneID	940933.
GenomeReviews	Gene locus CC_3269 in contig AE005673_GR.
KEGG	ccr:CC_3269.
NMPDR	fig|190650.1.peg.3243.
TIGR	CC_3269.
Phylogenomic databases
HOGENOM	Q9A3D5.
OMA	KSHTWIV.
Enzyme and pathway databases
BRENDA	3.1.3.25. 2191.
Family and domain databases
InterPro	IPR020583. Inositol_monoP_metal-BS. IPR000760. Inositol_monophosphatase. IPR020550. Inositol_monophosphatase_CS. [Graphical view]
PANTHER	PTHR20854. Inositol_P. 1 hit.
Pfam	PF00459. Inositol_P. 1 hit. [Graphical view]
PRINTS	PR00377. IMPHPHTASES.
ProDom	PD023420. Inositol_P. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00629. IMP_1. 1 hit. PS00630. IMP_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SUHB_CAUCR

Accession

Primary (citable) accession number: Q9A3D5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	June 1, 2001
Last modified:	November 3, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)