Q9A399 (Q9A399_CAUCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
NAD(P) transhydrogenase subunit alpha PIRNR PIRNR000203
EC=1.6.1.2 PIRNR PIRNR000203

Gene names

Ordered Locus Names:

CC_3305

Organism

Caulobacter crescentus (strain ATCC 19089 / CB15) [Reference proteome] [HAMAP]

Taxonomic identifier

190650 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter › Caulobacter crescentus

Protein attributes

Sequence length	378 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane By similarity. PIRNR PIRNR000203
Catalytic activity	NADPH + NAD+ = NADP+ + NADH. PIRNR PIRNR000203
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000203

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000203 NADP PIRNR PIRNR000203 Nucleotide-binding PIRNR PIRNR000203
Molecular function	Oxidoreductase PIRNR PIRNR000203
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proton transport Inferred from electronic annotation. Source: InterPro
Molecular_function	NAD(P)+ transhydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9A399 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: D7834807D9369E88	FASTA	378	39,048
	10 20 30 40 50 60 MAVIAVTKET RADETRVAAT PETVKKLGAA GFSVVIQAGA GTAASYPDAD YEAAGAKIAK 70 80 90 100 110 120 TAKDALKDAD VLFKVRAPES AEIAALKKGA IVAAALNPYQ DKETLDALAK AGATAIAMEF 130 140 150 160 170 180 IPRITRAQVM DMLSSQANLA GYRAVIEGAE AYGKALPMMM TAAGTVAAAK VFIMGVGVAG 190 200 210 220 230 240 LQAIATARRL GAVVTATDVR PATKEQVESL GAKFLAVEDE EFKNAQTAGG YAKEMSKEYQ 250 260 270 280 290 300 AKQAELVSSH IAKQDIVITT ALIPGRPAPK LVSAAQVASM KPGSILVDLA IEQGGNVEGA 310 320 330 340 350 360 KLNETVVTEG GVKILGHANL PGRIAADASA LYARNLFALS SLFTNKEGAF APNFEDEILQ 370 AAVVIRDGAI VHPNLKTA

References

[1]

"Complete genome sequence of Caulobacter crescentus." Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J. , Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19089 / CB15.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005673 Genomic DNA. Translation: AAK25267.1.
PIR	G87658.
RefSeq	NP_422099.1. NC_002696.2.
3D structure databases
HSSP	HSSP built from PDB template 1L7E based on UniProtKB Q60164.
ProteinModelPortal	Q9A399.
SMR	Q9A399. Positions 4-373.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK25267; AAK25267; CC_3305.
GeneID	940906.
KEGG	ccr:CC_3305.
PATRIC	21303640. VBICauCre124313_3312.
Phylogenomic databases
HOGENOM	HOG000022121.
KO	K00324.
OMA	FCVQTPS.
ProtClustDB	CLSK891408.
Family and domain databases
InterPro	IPR008143. Ala_DH/PNT_CS2. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. IPR026255. NADP_transhyd_a. [Graphical view]
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000203. NADP_transhydrogenase_alpha. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
PROSITE	PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9A399_CAUCR

Accession

Primary (citable) accession number: Q9A399

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)