Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9A2L1 (DAPB_CAUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase

Short name=DHPR
EC=1.3.1.26
Gene names
Name:dapB
Ordered Locus Names:CC_3550
OrganismCaulobacter crescentus (Caulobacter vibrioides)
Taxonomic identifier155892 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102

Subcellular location

Cytoplasm By similarity HAMAP MF_00102.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Diaminopimelate biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   LigandNADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processdiaminopimelate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionNADPH binding

Inferred from electronic annotation. Source: InterPro

dihydrodipicolinate reductase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257Dihydrodipicolinate reductase HAMAP MF_00102
PRO_0000141425

Sequences

Sequence LengthMass (Da)Tools
Q9A2L1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: B8AD3BB269A47AE4

FASTA25726,425
        10         20         30         40         50         60 
MSQPVKIAIA GANGRMGRAV AQALEGRSDA VVAARFERPG DAGEGLVARE TALAAAEAVI 

        70         80         90        100        110        120 
DFTLPEASVA LAEEAAANGG PALVIGSTGF SDEQLDRIDA AATKIVIVRS GNYSLGVNML 

       130        140        150        160        170        180 
MGLVRQAAAA LPAQDWDIEV FEAHHKRKID APSGTALMLG EAAAEGRGIN LAKVSDRGRD 

       190        200        210        220        230        240 
GVTGPRKDGD IGFSVVRGGG IIGEHSVIFA GESESLTLSH SAIDRGLFAR GAIAAAVWVK 

       250 
GKPPGLYDMQ DVLGFKK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005673 Genomic DNA. Translation: AAK25512.1.
PIRD87689.
RefSeqNP_422344.1. NC_002696.2.

3D structure databases

ProteinModelPortalQ9A2L1.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID943731.
GenomeReviewsGene locus CC_3550 in contig AE005673_GR.
KEGGccr:CC_3550.
NMPDRfig|190650.1.peg.3524.
PATRIC21304134. VBICauCre124313_3553.
TIGRCC_3550.

Phylogenomic databases

HOGENOMHBG594002.
OMAMVRVILN.
ProtClustDBPRK00048.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPB_CAUCR
AccessionPrimary (citable) accession number: Q9A2L1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: June 1, 2001
Last modified: January 25, 2012
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families