true2002-06-062024-03-27111DAPF_CAUVCComplete genome sequence of Caulobacter crescentus.Nierman W.C.Feldblyum T.V.Laub M.T.Paulsen I.T.Nelson K.E.Eisen J.A.Heidelberg J.F.Alley M.R.K.Ohta N.Maddock J.R.Potocka I.Nelson W.C.Newton A.Stephens C.Phadke N.D.Ely B.DeBoy R.T.Dodson R.J.Durkin A.S.Gwinn M.L.Haft D.H.Kolonay J.F.Smit J.Craven M.B.Khouri H.M.Shetty J.Berry K.J.Utterback T.R.Tran K.Wolf A.M.Vamathevan J.J.Ermolaeva M.D.White O.Salzberg S.L.Venter J.C.Shapiro L.Fraser C.M.doi:10.1073/pnas.0610292982001Proc. Natl. Acad. Sci. U.S.A.984136-4141NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]ATCC 19089 / CB15BacteriaDAP_epimeraseDAP_epimerase_ASDAP_epimerase_DapFDapFDIAMINOPIMELATE EPIMERASEDIAMINOPIMELATE EPIMERASE, CHLOROPLASTICDAP_epimeraseDiaminopimelate epimerase-likeDAP_EPIMERASEDiaminopimelate epimeraseDAP epimerase5.1.1.7PLP-independent amino acid racemasedapFCC_3686Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.Homodimer.Belongs to the diaminopimelate epimerase family.Diaminopimelate epimerase305461288Proton donor80Proton acceptor2271351718182166200218219228229Could be important to modulate the pK values of the two catalytic cysteine residues168Could be important to modulate the pK values of the two catalytic cysteine residuessubstrate2001-06-011305466823f092e57e6f15ee3cee6c4f0e0432MSRTFLKMNGLGNDFVVIQTLTEAFDPTPEQIRAIAKRPGVDGKGGIGCDQVIAIDPPRAEGASAYVRFWNSDGEVAGACGNGTRCVAWLLMQSAGKDAVAFDTVAGRLSGVAAGDKLVTVDMGPPGLDWTQIPLAEEMNTERVELQVGPIDAPLVHTPVCVSMGNPHVVFFVDAPVTDDFARGTGSLVEHHPLFPEGVNVGFAHIASRDHIRLKVWERGAGLTQACGTGACAAQVAAVRRGLTDRKARVEFDTGSLTIEWRESDGHVIMTGPITMEYAGKLPELVAAtrue