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Q9A1B7 (MURI_STRP1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate racemase
EC=5.1.1.3
Gene names
Name:murI
Synonyms:glr
Ordered Locus Names:SPy_0361, M5005_Spy0303
OrganismStreptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]
Taxonomic identifier301447 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP-Rule MF_00258

Catalytic activity

L-glutamate = D-glutamate. HAMAP-Rule MF_00258

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00258

Sequence similarities

Belongs to the aspartate/glutamate racemases family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 264264Glutamate racemase HAMAP-Rule MF_00258
PRO_0000095521

Secondary structure

1 .............................................. 264
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9A1B7 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: BD7A535F8B532274

FASTA26429,016
        10         20         30         40         50         60 
MDTRPIGFLD SGVGGLTVVC ELIRQLPHEK IVYIGDSARA PYGPRPKKQI KEYTWELVNF 

        70         80         90        100        110        120 
LLTQNVKMIV FACNTATAVA WEEVKAALDI PVLGVVLPGA SAAIKSTTKG QVGVIGTPMT 

       130        140        150        160        170        180 
VASDIYRKKI QLLAPSIQVR SLACPKFVPI VESNEMCSSI AKKIVYDSLA PLVGKIDTLV 

       190        200        210        220        230        240 
LGCTHYPLLR PIIQNVMGPS VKLIDSGAEC VRDISVLLNY FDINGNYHQK AVEHRFFTTA 

       250        260 
NPEIFQEIAS IWLKQKINVE HVTL

« Hide

References

[1]"Complete genome sequence of an M1 strain of Streptococcus pyogenes."
Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. expand/collapse author list , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E.
Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700294 / SF370 / Serotype M1.
[2]"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004092 Genomic DNA. Translation: AAK33406.1.
CP000017 Genomic DNA. Translation: AAZ50922.1.
RefSeqNP_268685.1. NC_002737.1.
YP_281667.1. NC_007297.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2OHGX-ray2.50A1-264[»]
2OHOX-ray2.25A/B1-264[»]
2OHVX-ray2.50A1-264[»]
ProteinModelPortalQ9A1B7.
SMRQ9A1B7. Positions 1-264.
ModBaseSearch...

Protein-protein interaction databases

STRING160490.SPy_0361.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK33406; AAK33406; SPy_0361.
AAZ50922; AAZ50922; M5005_Spy0303.
GeneID3572593.
900634.
KEGGspy:SPy_0361.
spz:M5005_Spy_0303.
PATRIC19714487. VBIStrPyo79812_0312.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0796.
HOGENOMHOG000262396.
KOK01776.
OMAVIMACNT.
ProtClustDBPRK00865.

Enzyme and pathway databases

BioCycSPYO160490:GJ81-319-MONOMER.
SPYO293653:GHFC-359-MONOMER.
SABIO-RKQ9A1B7.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.40.50.1860. 1 hit.
HAMAPMF_00258. Glu_racemase.
InterProIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS.
IPR004391. Glu_race.
[Graphical view]
PANTHERPTHR21198. PTHR21198. 1 hit.
PfamPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMSSF53681. Asp/Glu_race. 2 hits.
TIGRFAMsTIGR00067. glut_race. 1 hit.
PROSITEPS00923. ASP_GLU_RACEMASE_1. False negative.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9A1B7.

Entry information

Entry nameMURI_STRP1
AccessionPrimary (citable) accession number: Q9A1B7
Secondary accession number(s): Q490P6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: June 1, 2001
Last modified: May 29, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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