Reviewed, UniProtKB/Swiss-Prot Q9A186 (Y406_STRP1)

Names and origin

Protein names

Recommended name:
    UPF0011 protein SPy_0406/M5005_Spy0335

Gene names

Ordered Locus Names:

SPy_0406, M5005_Spy0335

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0011 family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 287	287	UPF0011 protein SPy_0406/M5005_Spy0335		PRO_0000211954

Sequences

	Sequence		Length	Mass (Da)
	Q9A186-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 7C14298A607EE301	FASTA	287	31,818
	10 20 30 40 50 60 MQVQKSFKDK KTSGTLYLVP TPIGNLQDMT FRAVATLKEV DFICAEDTRN TGLLLKHFDI 70 80 90 100 110 120 ATKQISFHEH NAYEKIPDLI DLLISGRSLA QVSDAGMPSI SDPGHDLVKA AIDSDIAVVA 130 140 150 160 170 180 LPGASAGITA LIASGLAPQP HVFYGFLPRK AGQQKAFFED KHHYPETQMF YESPYRIKDT 190 200 210 220 230 240 LTNMLACYGD RQVVLVRELT KLFEEYQRGS ISEILSYLEE TPLKGECLLI VAGAQADSEV 250 260 270 280 ELTADVDLVS LVQKEIQAGA KPNQAIKTIA KAYQVNRQEL YQQFHDL

References

[1]

"Complete genome sequence of an M1 strain of Streptococcus pyogenes." Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E. Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed: 11296296] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700294 / SF370 / Serotype M1.

[2]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed: 16088826] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE004092 Genomic DNA. Translation: AAK33438.1. CP000017 Genomic DNA. Translation: AAZ50954.1.
RefSeq	NP_268717.1. YP_281699.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3572586. 900666.
GenomeReviews	Gene locus SPy_0406 in contig AE004092_GR. Gene locus M5005_Spy0335 in contig CP000017_GR.
KEGG	spy:SPy_0406. spz:M5005_Spy_0335.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG529058.
OMA	ASDRFCF.
Enzyme and pathway databases
BioCyc	SPYO160490:SPY0406-MON. SPYO293653:M5005_SPY0335-MON.
Family and domain databases
InterPro	IPR000878. 4pyrrol_Mease. IPR014777. 4pyrrole_Mease_sub1. IPR008189. UPF0011. IPR018063. UPF0011_CS. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
PROSITE	PS01296. UPF0011. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y406_STRP1

Accession

Primary (citable) accession number: Q9A186
Secondary accession number(s): Q490L4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 2, 2001
Last sequence update:	June 1, 2001
Last modified:	December 15, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)