Q99ZK7 (Q99ZK7_STRP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Citrate lyase alpha chain/citrate CoA-transferase EMBL AAZ51525.1
EC=2.8.3.10 EMBL AAZ51525.1
EC=4.1.3.6 EMBL AAZ51525.1

Submitted name:
Putative citrate lyase, alpha subunit EMBL AAK34053.1
EC=4.1.3.6 EMBL AAK34053.1

Gene names

Name:	citF EMBL AAK34053.1
Ordered Locus Names:	M5005_Spy0907, SPy_1189

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	510 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL AAK34053.1 Transferase EMBL AAZ51525.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	acetyl-CoA metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	citrate lyase complex Inferred from electronic annotation. Source: InterPro
Molecular function	citrate (pro-3S)-lyase activity Inferred from electronic annotation. Source: EC citrate CoA-transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q99ZK7 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 459833B693E2EFA7	FASTA	510	54,991
	10 20 30 40 50 60 MVTNKLGRDI PQPYADQYGV FEGELANIKQ YDESSRRIKP VKPGDSKLLG SVREAIEKTG 70 80 90 100 110 120 LTDGMTISFH HHFREGDFIM NMVLEEIAKM GIKNLSIAPS SIANVHEPLI DHIKNGVVTN 130 140 150 160 170 180 ITSSGLRDKV GAAISEGLME NPVVIRSHGG RARAIASGDI HIDVAFLGAP SSDAYGNVNG 190 200 210 220 230 240 TKGKATCGSL GYAMIDAKYA DQVVILTDNL VPYPNTPISI PQTDVDYVVT VDAIGDPQGI 250 260 270 280 290 300 AKGATRFTKN PKELLIAEYA AKVITNSPYF KEGFSFQTGT GGASLAVTRF MREAMIKENI 310 320 330 340 350 360 KASFALGGIT NAMVELLEEE LVEKILDVQD FDHPSAVSLG KHAEHYEIDA NMYASPLSKG 370 380 390 400 410 420 AVINQLDTCI LSALEVDTNF NVNVMTGSDG VIRGASGGHC DTAFAAKMSL VISPLIRGRI 430 440 450 460 470 480 PTFVDEVNTV ITPGTSVDVI VTEVGIAINP NRQDLVDHFK SLNVPQFSIE ELKEKAYAIV 490 500 510 GTPERIQYGD KVVALIEYRD GSLMDVVYNV

References

[1]

"Complete genome sequence of an M1 strain of Streptococcus pyogenes." Ferretti J.J., McShan W.M., Ajdic D., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R. Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed: 11296296] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700294 / SF370 / Serotype M1.

[2]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed: 16088826] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004092 Genomic DNA. Translation: AAK34053.1. CP000017 Genomic DNA. Translation: AAZ51525.1.
RefSeq	NP_269332.1. NC_002737.1. YP_282270.1. NC_007297.1.
3D structure databases
ProteinModelPortal	Q99ZK7.
SMR	Q99ZK7. Positions 4-510.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000001605; EBSTRP00000001605; EBSTRG00000001605. EBSTRT00000028263; EBSTRP00000027281; EBSTRG00000028263.
GeneID	3571999. 901298.
GenomeReviews	Gene locus M5005_Spy0907 in contig AE004092_GR. Gene locus citF in contig CP000017_GR.
PATRIC	19715949. VBIStrPyo79812_1039.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000028641.
HOGENOM	HBG297040.
OMA	KGSVINQ.
ProtClustDB	CLSK874113.
Enzyme and pathway databases
BioCyc	SPYO160490:SPY1189-MONOMER. SPYO293653:M5005_SPY0907-MONOMER.
Family and domain databases
InterPro	IPR006472. Citrate_lyase_asu. [Graphical view]
Pfam	PF04223. CitF. 1 hit. [Graphical view]
PIRSF	PIRSF009451. Citrt_lyas_alpha. 1 hit.
TIGRFAMs	TIGR01584. CitF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q99ZK7_STRP1

Accession

Primary (citable) accession number: Q99ZK7
Secondary accession number(s): Q48YP7

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)