Q99ZG7 (Q99ZG7_STRP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lysyl aminopeptidase/alanine aminopeptidase EMBL AAZ51567.1
EC=3.4.11.15 EMBL AAZ51567.1
EC=3.4.11.2 EMBL AAZ51567.1

Submitted name:
Putative lysyl-aminopeptidase; aminopeptidase N EMBL AAK34094.1
EC=3.4.11.15 EMBL AAK34094.1

Gene names

Name:	pepN EMBL AAK34094.1
Ordered Locus Names:	M5005_Spy0949, SPy_1239

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pyogenes

Protein attributes

Sequence length	845 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Aminopeptidase EMBL AAK34094.1 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular_function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metallopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q99ZG7 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 6C19DD284274B420	FASTA	845	96,349
	10 20 30 40 50 60 MKTVEHLIET FVPENYNIFL DINRQTKTFT GNVAINGEAL DNHVAFHQKD LDIKSILLDN 70 80 90 100 110 120 EAVIYQVDND NEVVRVELPE TGMMTLVIEF SGSITDNMTG IYPSYYTKNG EKKEVISTQF 130 140 150 160 170 180 ESHFAREAFP CIDEPQAKAT FDLSLTFDQE IGEIALSNMP EVNIDRREET GLWTFDTTLR 190 200 210 220 230 240 MSSYLLAFAL GELHGKTVES KKGTTVGVYA TTAHPLSSLD FSLDIAVRVI NFYEDYFGVH 250 260 270 280 290 300 YPIPQSLNIA LPDFSSGAME NWGLITYREI YLLVDENSTV QSRQQVALVI AHEIAHQWFG 310 320 330 340 350 360 NLVTMKWWDD LWLNESFANM MEYVSIEAIE PSWKIIEDFQ TGGIPLALKR DATDGVQSVH 370 380 390 400 410 420 VEVNHPDEIN TLFDPAIVYA KGSRLMHMLR RFIGDRDFAI GLHHYFEKYQ YRNTVGRDLW 430 440 450 460 470 480 NILSDTSGKD VAAFMDAWLE QPGYPVLTAR LENDQLILSQ KQFFIGKGEE KGRLWPIPLN 490 500 510 520 530 540 TNWHGLPETL TEAEMVIPNF SQLAAENEGA LRFNIDNTAH YITDYQGSLL DALVTELAQL 550 560 570 580 590 600 DNTSALQVIQ ERRLLADSGL ISYAELVDLI AQLDDSKSYM VAEAVQQVVS GLKRFIDEGS 610 620 630 640 650 660 LAEKSFNRLV TTIYQEDFNQ HGFEKKADES DEDEMVRQVA LGRLWLAENQ TIIDGLRTIF 670 680 690 700 710 720 EAYQNNIASI PAAVRRLVLA NQMKYFETDS LVDIYFETYV ATTDNNLRSD LTVAFSQTKQ 730 740 750 760 770 780 PTTIRRILVS LKDKDIIKPQ DLSYWYNALL GQSFTQDIIW EWARENWDWI KSALGGDMSF 790 800 810 820 830 840 DKFVIYPASN FKTPKHLAEY KSFFEPKLDD MAISRNITMG INEIEARVAL ITKEKEAVIA ALSHY

References

[1]

"Complete genome sequence of an M1 strain of Streptococcus pyogenes." Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E. Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700294 / SF370 / Serotype M1.

[2]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004092 Genomic DNA. Translation: AAK34094.1. CP000017 Genomic DNA. Translation: AAZ51567.1.
RefSeq	NP_269373.1. NC_002737.1. YP_282312.1. NC_007297.1.
3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	M01.002.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK34094; AAK34094; SPy_1239. AAZ51567; AAZ51567; M5005_Spy0949.
GeneID	3571963. 901339.
KEGG	spy:SPy_1239. spz:M5005_Spy_0949.
PATRIC	19716033. VBIStrPyo79812_1081.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000235375.
KO	K01256.
OMA	YLDINRE.
ProtClustDB	CLSK876725.
Family and domain databases
InterPro	IPR024571. DUF3358. IPR001930. Peptidase_M1. IPR014782. Peptidase_M1_N. [Graphical view]
PANTHER	PTHR11533. PTHR11533. 1 hit.
Pfam	PF11838. DUF3358. 1 hit. PF01433. Peptidase_M1. 1 hit. [Graphical view]
PRINTS	PR00756. ALADIPTASE.
ProtoNet	Search...

Entry information

Entry name

Q99ZG7_STRP1

Accession

Primary (citable) accession number: Q99ZG7
Secondary accession number(s): Q48YK5

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)