Q99YX0 (Q99YX0_STRP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Deoxyribodipyrimidine photolyase EMBL AAZ51854.1
EC=4.1.99.3 EMBL AAZ51854.1

Submitted name:
Putative deoxyribodipyrimidine photolyase EMBL AAK34302.1
EC=4.1.99.3 EMBL AAK34302.1

Gene names

Name:	phr EMBL AAK34302.1
Ordered Locus Names:	M5005_Spy1236, SPy_1505

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pyogenes

Protein attributes

Sequence length	469 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the DNA photolyase class-1 family. RuleBase RU004182

Ontologies

Keywords
Ligand	Chromophore RuleBase RU004291 FAD RuleBase RU004291 Flavoprotein RuleBase RU004291
Molecular function	Lyase EMBL AAK34302.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: InterPro protein-chromophore linkage Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	deoxyribodipyrimidine photo-lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q99YX0 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: C41FD3C09C98F34D	FASTA	469	54,893
	10 20 30 40 50 60 MVSVMWFRRD LRIDDQKALA HAIASQSPTL CVFQFNKEQL NLLHSRNQSS FITSVLAFRK 70 80 90 100 110 120 LLKCEGIDLY LMYGDLMTCF EQLLTQLKDW TDVYFNYDES GYGRLRDQKA AQFFKKNGIA 130 140 150 160 170 180 VHTYQDHYLH GSQEIINQSG QPYKVFTPYY RIWQNYPKET PIKVELSQGR WLNLETPDDV 190 200 210 220 230 240 LRTVESFKDE KYQDVATFDE ASKQLNRFIQ DQLAAYHANR DFPAQLGTSR LSPFLRIGAI 250 260 270 280 290 300 GIRTVYHAVR QAPNSLGQAT FLKELAWRDF YNMVYVAYPD QKTQPIQKAF SQIEWVNNPD 310 320 330 340 350 360 WFQLWKEGKT GYPIVDAAML QLQKTGWMHN RLRMIVASFL TKDLLCDWRL GEQYFQQQLI 370 380 390 400 410 420 DYDAASNIGG WQWAASTGTD AVPYFRIFNP VTQGKRFDPK GEFIKAYLPQ LEHVPEKYLH 430 440 450 460 EPWKMPKNLQ ESVSCIIGTD YPQPIVDHAK QREQAIAKYE WAKEKAKIE

References

[1]

"Complete genome sequence of an M1 strain of Streptococcus pyogenes." Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E. Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700294 / SF370 / Serotype M1.

[2]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004092 Genomic DNA. Translation: AAK34302.1. CP000017 Genomic DNA. Translation: AAZ51854.1.
RefSeq	NP_269581.1. NC_002737.1. YP_282599.1. NC_007297.1.
3D structure databases
HSSP	HSSP built from PDB template 1DNP based on UniProtKB P00914.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK34302; AAK34302; SPy_1505. AAZ51854; AAZ51854; M5005_Spy1236.
GeneID	3571665. 901552.
KEGG	spy:SPy_1505. spz:M5005_Spy_1236.
PATRIC	19716498. VBIStrPyo79812_1313.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000245621.
KO	K01669.
OMA	GDLANNQ.
ProtClustDB	CLSK698748.
Family and domain databases
Gene3D	3.40.50.620. 1 hit.
InterPro	IPR002081. Cryptochrome/DNA_photolyase_1. IPR018394. DNA_photolyase_1_CS_C. IPR006050. DNA_photolyase_N. IPR005101. Photolyase_FAD-bd/Cryptochr_C. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Pfam	PF00875. DNA_photolyase. 1 hit. PF03441. FAD_binding_7. 1 hit. [Graphical view]
PRINTS	PR00147. DNAPHOTLYASE.
SUPFAM	SSF52425. DNA_photolyase_N. 1 hit. SSF48173. Photolyase_FAD-bd/Cryptochr_C. 1 hit.
PROSITE	PS00691. DNA_PHOTOLYASES_1_2. 1 hit. PS51645. PHR_CRY_ALPHA_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q99YX0_STRP1

Accession

Primary (citable) accession number: Q99YX0
Secondary accession number(s): Q48XS1

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)