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Q99YP9 (Q99YP9_STRP1) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=3.2.1.21 EMBL AAZ51931.1

Putative beta-glucosidase EMBL AAK34377.1
Gene names
Ordered Locus Names:M5005_Spy1313 EMBL AAZ51931.1, SPy_1599 EMBL AAK34377.1
OrganismStreptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]
Taxonomic identifier301447 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length480 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 1 family. RuleBase RU003690

Ontologies

Keywords
   Molecular functionGlycosidase EMBL AAZ51931.1
Hydrolase
   Technical term3D-structure PDB 4B3K PDB 4B3L
Complete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q99YP9 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: D25DB251F765E16F

FASTA48055,111
        10         20         30         40         50         60 
MLAFPKEFWW GGATSGPQSE GRFAKQHRNL FDYWYEEEPD LFYDYVGPDT ASDAYHQIES 

        70         80         90        100        110        120 
DLTLLASLGH NSYRTSIQWT RLIDDFEQAT INPDGLAYYN RVIDACLANG IRPVINLHHF 

       130        140        150        160        170        180 
DLPIALYQAY GGWESKHVVD LFVAFSKVCF EQFGDRVKDW FVHNEPMVVV EGSYLMQFHY 

       190        200        210        220        230        240 
PAIVDGKKAV QVAYNLALAT AKVIQAYRRG PAELSDGRIG TILNLTPAYP ASQSEADMAA 

       250        260        270        280        290        300 
AHFAELWNND LFMEAAVHGK FPEELVAVLK KDGVLWQSTP EELALIAENR VDYLGLNFYH 

       310        320        330        340        350        360 
PKRVKAPDAI PVISPSWSPE WYYDPYLMPG RRMNVDKGWE IYPEAVYDIA IKMRDHYDNI 

       370        380        390        400        410        420 
PWFLSENGVG ISGEDRYRDE TGQIQDDYRI QFLKEHLTYL HKGIEAGSNC FGYHVWTPID 

       430        440        450        460        470        480 
GWSWLNAYKN RYGLVENNIH TQVRRPKASA YWFKKVATHN RLISLEVMEE FGGSASHLSD 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of an M1 strain of Streptococcus pyogenes."
Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. expand/collapse author list , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E.
Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700294 / SF370 / Serotype M1 and SF370 EMBL AAK34377.1.
[2]"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-947 / MGAS5005 / Serotype M1 and MGAS5005 EMBL AAZ51931.1.
[3]"Structure and activity of the Streptococcus pyogenes family GH1 6-phospho-?-glucosidase SPy1599."
Stepper J., Dabin J., Eklof J.M., Thongpoo P., Kongsaeree P., Taylor E.J., Turkenburg J.P., Brumer H., Davies G.J.
Acta Crystallogr. D 69:16-23(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.51 ANGSTROMS) OF 2-480.
[4]"Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences."
Nasser W., Beres S.B., Olsen R.J., Dean M.A., Rice K.A., Long S.W., Kristinsson K.G., Gottfredsson M., Vuopio J., Raisanen K., Cauget D., Steinbakk M., Lowe D.E., McGeere A., Darenberg J., Henriques-Normark B., van Benedeng C.A., Hoffmann S., Musser J.M.
Proc. Natl. Acad. Sci. U.S.A. 111:E1768-E1776(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MGAS5005.
[5]"Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences."
Nasser W., Beres S.B., Olsen R.J., Dean M.A., Rice K.A., Long S.W., Kristinsson K.G., Gottfredsson M., Vuopio J., Raisanen K., Cauget D., Steinbakk M., Lowe D.E., McGeere A., Darenberg J., Henriques-Normark B., van Benedeng C.A., Hoffmann S., Mussera J.M.
Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2014)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SF370.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004092 Genomic DNA. Translation: AAK34377.1.
CP000017 Genomic DNA. Translation: AAZ51931.1.
RefSeqNP_269656.1. NC_002737.1.
YP_282676.1. NC_007297.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4B3KX-ray2.60A/B/C/D/E/F2-480[»]
4B3LX-ray2.51A/B/C/D/E/F2-480[»]
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK34377; AAK34377; SPy_1599.
AAZ51931; AAZ51931; M5005_Spy1313.
GeneID3571590.
901846.
KEGGspy:SPy_1599.
spz:M5005_Spy_1313.
PATRIC19716662. VBIStrPyo79812_1394.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000088632.
KOK05350.
OMAINEFIAQ.
OrthoDBEOG60658J.

Enzyme and pathway databases

BioCycSPYO160490:GJ81-1316-MONOMER.
SPYO293653:GHFC-1373-MONOMER.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001360. Glyco_hydro_1.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10353. PTHR10353. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ99YP9_STRP1
AccessionPrimary (citable) accession number: Q99YP9
Secondary accession number(s): Q48XJ4
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)