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Protein
Submitted name:

Uncharacterized protein

Gene

SPy_1604

Organism
Streptococcus pyogenes serotype M1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi13 – 131Zinc; via tele nitrogenCombined sources
Metal bindingi15 – 151ZincCombined sources
Metal bindingi125 – 1251ZincCombined sources
Metal bindingi351 – 3511Zinc; via tele nitrogenCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-1320-MONOMER.
SPYO293653:GHFC-1377-MONOMER.
BRENDAi3.2.1.114. 5935.

Protein family/group databases

CAZyiGH38. Glycoside Hydrolase Family 38.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:SPy_1604Imported
OrganismiStreptococcus pyogenes serotype M1Imported
Taxonomic identifieri301447 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000750 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiQ99YP5.

Interactioni

Protein-protein interaction databases

STRINGi160490.SPy_1604.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2WYHX-ray1.90A/B1-901[»]
2WYIX-ray2.60A/B1-901[»]
ProteinModelPortaliQ99YP5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini297 – 37074Alpha-mann_midInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4107VTQ. Bacteria.
COG0383. LUCA.
HOGENOMiHOG000231434.
KOiK01191.
OMAiLENTDRY.
OrthoDBiEOG6N0HF2.

Family and domain databases

Gene3Di1.20.1270.50. 1 hit.
3.20.110.10. 1 hit.
InterProiIPR011013. Gal_mutarotase_SF_dom.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR027291. Glyco_hydro_38/57_N.
IPR011682. Glyco_hydro_38_C.
IPR015341. Glyco_hydro_38_cen.
IPR000602. Glyco_hydro_38_N.
IPR028995. Glyco_hydro_57/38_cen.
[Graphical view]
PfamiPF09261. Alpha-mann_mid. 1 hit.
PF01074. Glyco_hydro_38. 1 hit.
PF07748. Glyco_hydro_38C. 1 hit.
[Graphical view]
SMARTiSM00872. Alpha-mann_mid. 1 hit.
[Graphical view]
SUPFAMiSSF74650. SSF74650. 2 hits.
SSF88688. SSF88688. 1 hit.
SSF88713. SSF88713. 1 hit.

Sequencei

Sequence statusi: Complete.

Q99YP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATKKVHIIS HSHWDREWYM AYEQHHMRLI NLIDDLLEVF QTDPDFHSFH
60 70 80 90 100
LDGQTIILDD YLKVRPEREP EIRQAIASGK LRIGPFYILQ DDFLTSSESN
110 120 130 140 150
VRNMLIGKED CDRWGASVPL GYFPDTFGNM GQTPQLMLKA GLQAAAFGRG
160 170 180 190 200
IRPTGFNNQV DTSEKYSSQF SEISWQGPDN SRILGLLFAN WYSNGNEIPT
210 220 230 240 250
TEAEARLFWD KKLADAERFA STKHLLMMNG CDHQPVQLDV TKAIALANQL
260 270 280 290 300
YPDYEFVHSC FEDYLADLAD DLPENLSTVQ GEITSQETDG WYTLANTASA
310 320 330 340 350
RIYLKQANTR VSRQLENITE PLAAMAYEVT STYPHDQLRY AWKTLMQNHP
360 370 380 390 400
HDSICGCSVD SVHREMMTRF EKAYEVGHYL AKEAAKQIAD AIDTRDFPMD
410 420 430 440 450
SQPFVLFNTS GHSKTSVAEL SLTWKKYHFG QRFPKEVYQE AQEYLARLSQ
460 470 480 490 500
SFQIIDTSGQ VRPEAEILGT SIAFDYDLPK RSFREPYFAI KVRLRLPITL
510 520 530 540 550
PAMSWKTLAL KLGNETTPSE TVSLYDDSNQ CLENGFLKVM IQTDGRLTIT
560 570 580 590 600
DKQSGLIYQD LLRFEDCGDI GNEYISRQPN HDQPFYADQG TIKLNIISNT
610 620 630 640 650
AQVAELEIQQ TFAIPISADK LLQAEMEAVI DITERQARRS QEKAELTLTT
660 670 680 690 700
LIRMEKNNPR LQFTTRFDNQ MTNHRLRVLF PTHLKTDHHL ADSIFETVKR
710 720 730 740 750
PNHPDATFWK NPSNPQHQEC FVSLFDGENG VTIGNYGLNE YEILPDTNTI
760 770 780 790 800
AITLLRSVGE MGDWGYFPTP EAQCLGKHSL SYSFESITKQ TQFASYWRAQ
810 820 830 840 850
EGQVPVITTQ TNQHEGTLAA EYSYLTGTND QVALTAFKRR LADNALITRS
860 870 880 890 900
YNLSNDKTCD FSLSLPNYNA KVTNLLEKDS KQSTPSQLGK AEILTLAWKK

Q
Length:901
Mass (Da):102,751
Last modified:June 1, 2001 - v1
Checksum:iAB87B07001A83367
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA. Translation: AAK34381.1.
RefSeqiNP_269660.1. NC_002737.2.

Genome annotation databases

EnsemblBacteriaiAAK34381; AAK34381; SPy_1604.
GeneIDi901852.
KEGGispy:SPy_1604.
PATRICi19716670. VBIStrPyo79812_1398.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004092 Genomic DNA. Translation: AAK34381.1.
RefSeqiNP_269660.1. NC_002737.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2WYHX-ray1.90A/B1-901[»]
2WYIX-ray2.60A/B1-901[»]
ProteinModelPortaliQ99YP5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160490.SPy_1604.

Protein family/group databases

CAZyiGH38. Glycoside Hydrolase Family 38.

Proteomic databases

PaxDbiQ99YP5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK34381; AAK34381; SPy_1604.
GeneIDi901852.
KEGGispy:SPy_1604.
PATRICi19716670. VBIStrPyo79812_1398.

Phylogenomic databases

eggNOGiENOG4107VTQ. Bacteria.
COG0383. LUCA.
HOGENOMiHOG000231434.
KOiK01191.
OMAiLENTDRY.
OrthoDBiEOG6N0HF2.

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-1320-MONOMER.
SPYO293653:GHFC-1377-MONOMER.
BRENDAi3.2.1.114. 5935.

Family and domain databases

Gene3Di1.20.1270.50. 1 hit.
3.20.110.10. 1 hit.
InterProiIPR011013. Gal_mutarotase_SF_dom.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR027291. Glyco_hydro_38/57_N.
IPR011682. Glyco_hydro_38_C.
IPR015341. Glyco_hydro_38_cen.
IPR000602. Glyco_hydro_38_N.
IPR028995. Glyco_hydro_57/38_cen.
[Graphical view]
PfamiPF09261. Alpha-mann_mid. 1 hit.
PF01074. Glyco_hydro_38. 1 hit.
PF07748. Glyco_hydro_38C. 1 hit.
[Graphical view]
SMARTiSM00872. Alpha-mann_mid. 1 hit.
[Graphical view]
SUPFAMiSSF74650. SSF74650. 2 hits.
SSF88688. SSF88688. 1 hit.
SSF88713. SSF88713. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700294 / SF370 / Serotype M1Imported.
  2. "Structure and kinetic investigation of Streptococcus pyogenes family GH38 alpha-mannosidase."
    Suits M.D., Zhu Y., Taylor E.J., Walton J., Zechel D.L., Gilbert H.J., Davies G.J.
    PLoS ONE 5:e9006-e9006(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ99YP5_STRP1
AccessioniPrimary (citable) accession number: Q99YP5
Secondary accession number(s): Q48XJ0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: March 16, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.