Q99YN0 (Q99YN0_STRP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine protein kinase EMBL AAZ51953.1
EC=2.7.11.1 EMBL AAZ51953.1

Gene names

Ordered Locus Names:

M5005_Spy1335 EMBL AAZ51953.1, SPy_1625

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pyogenes

Protein attributes

Sequence length	632 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305 EMBL AAZ51953.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW penicillin binding Inferred from electronic annotation. Source: InterPro protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q99YN0 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 2B6F2D985AB8890A	FASTA	632	68,860
	10 20 30 40 50 60 MIQIGKLFAG RYRILKSIGR GGMADVYLAN DLILDNEDVA IKVLRTNYQT DQVAVARFQR 70 80 90 100 110 120 EARAMAELNH PNIVAIRDIG EEDGQQFLVM EYVDGADLKR YIQNHAPLSN NEVVRIMEEV 130 140 150 160 170 180 LSAMTLAHQK GIVHRDLKPQ NILLTKEGVV KVTDFGIAVA FAETSLTQTN SMLGSVHYLS 190 200 210 220 230 240 PEQARGSKAT IQSDIYAMGI MLFEMLTGHI PYDGDSAVTI ALQHFQKPLP SIIEENHNVP 250 260 270 280 290 300 QALENVVIRA TAKKLSDRYG STFEMSRDLM TALSYNRSRE RKIIFENVES TKPLPKVASG 310 320 330 340 350 360 PTASVKLSPP TPTVLTQESR LDQTNQTDAL QPPTKKKKSG RFLGTLFKIL FSFFIVGVAL 370 380 390 400 410 420 FTYLILTKPT SVKVPNVAGT SLKVAKQELY DVGLKVGKIR QIESDTVAEG NVVRTDPKAG 430 440 450 460 470 480 TAKRQGSSIT LYVSIGNKGF DMENYKGLDY QEAMNSLIET YGVPKSKIKI ERIVTNEYPE 490 500 510 520 530 540 NTVISQSPSA GDKFNPNGKS KITLSVAVSD TITMPMVTEY SYADAVNTLT ALGIDASRIK 550 560 570 580 590 600 AYVPSSSSAT GFVPIHSPSS KAIVSGQSPY YGTSLSLSDK GEISLYLYPE ETHSSSSSSS 610 620 630 STSSSNSSSI NDSTAPGSNT ELSPSETTSQ TP

References

[1]

"Complete genome sequence of an M1 strain of Streptococcus pyogenes." Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E. Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700294 / SF370 / Serotype M1.

[2]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1 and MGAS5005 EMBL AAZ51953.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004092 Genomic DNA. Translation: AAK34396.1. CP000017 Genomic DNA. Translation: AAZ51953.1.
RefSeq	NP_269675.1. NC_002737.1. YP_282698.1. NC_007297.1.
3D structure databases
ModBase	Search...
PTM databases
PhosSite	P12031493.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK34396; AAK34396; SPy_1625. AAZ51953; AAZ51953; M5005_Spy1335.
GeneID	3571566. 901877.
KEGG	spy:SPy_1625. spz:M5005_Spy_1335.
PATRIC	19716730. VBIStrPyo79812_1417.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000037186.
KO	K08884.
OMA	VIQEGTK.
ProtClustDB	CLSK698795.
Enzyme and pathway databases
BioCyc	SPYO160490:GJ81-1347-MONOMER. SPYO293653:GHFC-1406-MONOMER.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR005543. PASTA. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF03793. PASTA. 3 hits. PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00740. PASTA. 3 hits. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS51178. PASTA. 3 hits. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q99YN0_STRP1

Accession

Primary (citable) accession number: Q99YN0
Secondary accession number(s): Q48XH2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	May 29, 2013
This is version 98 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)