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Q99YN0 (Q99YN0_STRP1) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=2.7.11.1 EMBL AAZ51953.1

Uncharacterized protein EMBL AAK34396.1
Gene names
Ordered Locus Names:M5005_Spy1335 EMBL AAZ51953.1, SPy_1625 EMBL AAK34396.1
OrganismStreptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]
Taxonomic identifier301447 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length632 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily. RuleBase RU000305

Sequences

Sequence LengthMass (Da)Tools
Q99YN0 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 2B6F2D985AB8890A

FASTA63268,860
        10         20         30         40         50         60 
MIQIGKLFAG RYRILKSIGR GGMADVYLAN DLILDNEDVA IKVLRTNYQT DQVAVARFQR 

        70         80         90        100        110        120 
EARAMAELNH PNIVAIRDIG EEDGQQFLVM EYVDGADLKR YIQNHAPLSN NEVVRIMEEV 

       130        140        150        160        170        180 
LSAMTLAHQK GIVHRDLKPQ NILLTKEGVV KVTDFGIAVA FAETSLTQTN SMLGSVHYLS 

       190        200        210        220        230        240 
PEQARGSKAT IQSDIYAMGI MLFEMLTGHI PYDGDSAVTI ALQHFQKPLP SIIEENHNVP 

       250        260        270        280        290        300 
QALENVVIRA TAKKLSDRYG STFEMSRDLM TALSYNRSRE RKIIFENVES TKPLPKVASG 

       310        320        330        340        350        360 
PTASVKLSPP TPTVLTQESR LDQTNQTDAL QPPTKKKKSG RFLGTLFKIL FSFFIVGVAL 

       370        380        390        400        410        420 
FTYLILTKPT SVKVPNVAGT SLKVAKQELY DVGLKVGKIR QIESDTVAEG NVVRTDPKAG 

       430        440        450        460        470        480 
TAKRQGSSIT LYVSIGNKGF DMENYKGLDY QEAMNSLIET YGVPKSKIKI ERIVTNEYPE 

       490        500        510        520        530        540 
NTVISQSPSA GDKFNPNGKS KITLSVAVSD TITMPMVTEY SYADAVNTLT ALGIDASRIK 

       550        560        570        580        590        600 
AYVPSSSSAT GFVPIHSPSS KAIVSGQSPY YGTSLSLSDK GEISLYLYPE ETHSSSSSSS 

       610        620        630 
STSSSNSSSI NDSTAPGSNT ELSPSETTSQ TP 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of an M1 strain of Streptococcus pyogenes."
Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L. expand/collapse author list , White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E.
Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700294 / SF370 / Serotype M1 and SF370 EMBL AAK34396.1.
[2]"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-947 / MGAS5005 / Serotype M1 and MGAS5005 EMBL AAZ51953.1.
[3]"Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences."
Nasser W., Beres S.B., Olsen R.J., Dean M.A., Rice K.A., Long S.W., Kristinsson K.G., Gottfredsson M., Vuopio J., Raisanen K., Cauget D., Steinbakk M., Lowe D.E., McGeere A., Darenberg J., Henriques-Normark B., van Benedeng C.A., Hoffmann S., Musser J.M.
Proc. Natl. Acad. Sci. U.S.A. 111:E1768-E1776(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MGAS5005.
[4]"Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences."
Nasser W., Beres S.B., Olsen R.J., Dean M.A., Rice K.A., Long S.W., Kristinsson K.G., Gottfredsson M., Vuopio J., Raisanen K., Cauget D., Steinbakk M., Lowe D.E., McGeere A., Darenberg J., Henriques-Normark B., van Benedeng C.A., Hoffmann S., Mussera J.M.
Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2014)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SF370.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004092 Genomic DNA. Translation: AAK34396.1.
CP000017 Genomic DNA. Translation: AAZ51953.1.
RefSeqNP_269675.1. NC_002737.1.
YP_282698.1. NC_007297.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

PTM databases

PhosSiteP12031493.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK34396; AAK34396; SPy_1625.
AAZ51953; AAZ51953; M5005_Spy1335.
GeneID3571566.
901877.
KEGGspy:SPy_1625.
spz:M5005_Spy_1335.
PATRIC19716730. VBIStrPyo79812_1417.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000037186.
KOK08884.
OMAREMNEDI.
OrthoDBEOG6B35XT.

Enzyme and pathway databases

BioCycSPYO160490:GJ81-1347-MONOMER.
SPYO293653:GHFC-1406-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ99YN0_STRP1
AccessionPrimary (citable) accession number: Q99YN0
Secondary accession number(s): Q48XH2
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)