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Q99YN0

- Q99YN0_STRP1

UniProt

Q99YN0 - Q99YN0_STRP1

Protein
Submitted name:

Serine/threonine protein kinase

Gene

M5005_Spy1335

Organism
Streptococcus pyogenes serotype M1
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 110 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. penicillin binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinaseUniRule annotationImported, Transferase

    Enzyme and pathway databases

    BioCyciSPYO160490:GJ81-1347-MONOMER.
    SPYO293653:GHFC-1406-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Serine/threonine protein kinaseImported (EC:2.7.11.1Imported)
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Ordered Locus Names:M5005_Spy1335Imported, SPy_1625Imported
    OrganismiStreptococcus pyogenes serotype M1Imported
    Taxonomic identifieri301447 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002702: Chromosome

    PTM / Processingi

    PTM databases

    PhosSiteiP12031493.

    Structurei

    3D structure databases

    ProteinModelPortaliQ99YN0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the protein kinase superfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000037186.
    KOiK08884.
    OMAiREMNEDI.
    OrthoDBiEOG6B35XT.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00740. PASTA. 3 hits.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51178. PASTA. 3 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q99YN0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIQIGKLFAG RYRILKSIGR GGMADVYLAN DLILDNEDVA IKVLRTNYQT    50
    DQVAVARFQR EARAMAELNH PNIVAIRDIG EEDGQQFLVM EYVDGADLKR 100
    YIQNHAPLSN NEVVRIMEEV LSAMTLAHQK GIVHRDLKPQ NILLTKEGVV 150
    KVTDFGIAVA FAETSLTQTN SMLGSVHYLS PEQARGSKAT IQSDIYAMGI 200
    MLFEMLTGHI PYDGDSAVTI ALQHFQKPLP SIIEENHNVP QALENVVIRA 250
    TAKKLSDRYG STFEMSRDLM TALSYNRSRE RKIIFENVES TKPLPKVASG 300
    PTASVKLSPP TPTVLTQESR LDQTNQTDAL QPPTKKKKSG RFLGTLFKIL 350
    FSFFIVGVAL FTYLILTKPT SVKVPNVAGT SLKVAKQELY DVGLKVGKIR 400
    QIESDTVAEG NVVRTDPKAG TAKRQGSSIT LYVSIGNKGF DMENYKGLDY 450
    QEAMNSLIET YGVPKSKIKI ERIVTNEYPE NTVISQSPSA GDKFNPNGKS 500
    KITLSVAVSD TITMPMVTEY SYADAVNTLT ALGIDASRIK AYVPSSSSAT 550
    GFVPIHSPSS KAIVSGQSPY YGTSLSLSDK GEISLYLYPE ETHSSSSSSS 600
    STSSSNSSSI NDSTAPGSNT ELSPSETTSQ TP 632
    Length:632
    Mass (Da):68,860
    Last modified:June 1, 2001 - v1
    Checksum:i2B6F2D985AB8890A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004092 Genomic DNA. Translation: AAK34396.1.
    CP000017 Genomic DNA. Translation: AAZ51953.1.
    RefSeqiNP_269675.1. NC_002737.1.
    YP_282698.1. NC_007297.1.

    Genome annotation databases

    EnsemblBacteriaiAAK34396; AAK34396; SPy_1625.
    AAZ51953; AAZ51953; M5005_Spy1335.
    GeneIDi3571566.
    901877.
    KEGGispy:SPy_1625.
    spz:M5005_Spy_1335.
    PATRICi19716730. VBIStrPyo79812_1417.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004092 Genomic DNA. Translation: AAK34396.1 .
    CP000017 Genomic DNA. Translation: AAZ51953.1 .
    RefSeqi NP_269675.1. NC_002737.1.
    YP_282698.1. NC_007297.1.

    3D structure databases

    ProteinModelPortali Q99YN0.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosSitei P12031493.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK34396 ; AAK34396 ; SPy_1625 .
    AAZ51953 ; AAZ51953 ; M5005_Spy1335 .
    GeneIDi 3571566.
    901877.
    KEGGi spy:SPy_1625.
    spz:M5005_Spy_1335.
    PATRICi 19716730. VBIStrPyo79812_1417.

    Phylogenomic databases

    HOGENOMi HOG000037186.
    KOi K08884.
    OMAi REMNEDI.
    OrthoDBi EOG6B35XT.

    Enzyme and pathway databases

    BioCyci SPYO160490:GJ81-1347-MONOMER.
    SPYO293653:GHFC-1406-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00740. PASTA. 3 hits.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51178. PASTA. 3 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SF370Imported.
    2. "Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
      Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
      J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-947 / MGAS5005 / Serotype M1Imported and MGAS5005Imported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MGAS5005.
    4. "Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences."
      Nasser W., Beres S.B., Olsen R.J., Dean M.A., Rice K.A., Long S.W., Kristinsson K.G., Gottfredsson M., Vuopio J., Raisanen K., Cauget D., Steinbakk M., Lowe D.E., McGeere A., Darenberg J., Henriques-Normark B., van Benedeng C.A., Hoffmann S., Mussera J.M.
      Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2014)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: SF370.

    Entry informationi

    Entry nameiQ99YN0_STRP1
    AccessioniPrimary (citable) accession number: Q99YN0
    Secondary accession number(s): Q48XH2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 110 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3