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Q99YB6

- Q99YB6_STRP1

UniProt

Q99YB6 - Q99YB6_STRP1

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Protein
Submitted name:

Aspartate aminotransferase

Gene

M5005_Spy1513

Organism
Streptococcus pyogenes serotype M1
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  2. L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Enzyme and pathway databases

BioCyciSPYO160490:GJ81-1467-MONOMER.
SPYO293653:GHFC-1585-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Aspartate aminotransferaseImported (EC:2.6.1.1Imported)
Submitted name:
Putative aminotransferaseImported (EC:2.6.1.-Imported)
Gene namesi
Ordered Locus Names:M5005_Spy1513Imported, SPy_1779Imported
OrganismiStreptococcus pyogenes serotype M1Imported
Taxonomic identifieri301447 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002702: Chromosome

Structurei

3D structure databases

ProteinModelPortaliQ99YB6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000223042.
KOiK14260.
OMAiENELIIF.
OrthoDBiEOG6X9MJ6.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q99YB6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIIEKSSKL EHVAYDIRGP VLDEANRMIA SGEKILRLNT GNPAAFGFEA
60 70 80 90 100
PDEVIRDLIV NARLSEGYSD SKGIFSARKA IMQYCQLKGF PDVDIEDIYL
110 120 130 140 150
GNGVSELISI SLQALLDNGD EVLVPMPDYP LWTACVSLGG GKAVHYLCDE
160 170 180 190 200
EAGWYPDIAD IKSKITSRTK AIVVINPNNP TGALYPKEIL EDIVALAREH
210 220 230 240 250
QLIIFADEIY DRLVMDGKEH IAIASLAPDV FCVSMNGLSK SHRIAGFRVG
260 270 280 290 300
WMVLSGPKDH VKGYIEGLNM LANMRLCSNV LAQQVVQTSL GGHQSVDALL
310 320 330 340 350
LPGGRIFEQR NFIYEAINAI PGLSAVKPEA GLYLFPKIDR QMYRIDDDEE
360 370 380 390 400
FVLQLLKQEK VMLVHGRGFN WKDPDHFRIV YLPSVEELED VQEKITRVLY

QYRR
Length:404
Mass (Da):45,223
Last modified:June 1, 2001 - v1
Checksum:i30D9D2499183A217
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004092 Genomic DNA. Translation: AAK34514.1.
CP000017 Genomic DNA. Translation: AAZ52131.1.
RefSeqiNP_269793.1. NC_002737.1.
YP_282876.1. NC_007297.1.

Genome annotation databases

EnsemblBacteriaiAAK34514; AAK34514; SPy_1779.
AAZ52131; AAZ52131; M5005_Spy1513.
GeneIDi3571397.
902010.
KEGGispy:SPy_1779.
spz:M5005_Spy_1513.
PATRICi19716992. VBIStrPyo79812_1547.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004092 Genomic DNA. Translation: AAK34514.1 .
CP000017 Genomic DNA. Translation: AAZ52131.1 .
RefSeqi NP_269793.1. NC_002737.1.
YP_282876.1. NC_007297.1.

3D structure databases

ProteinModelPortali Q99YB6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK34514 ; AAK34514 ; SPy_1779 .
AAZ52131 ; AAZ52131 ; M5005_Spy1513 .
GeneIDi 3571397.
902010.
KEGGi spy:SPy_1779.
spz:M5005_Spy_1513.
PATRICi 19716992. VBIStrPyo79812_1547.

Phylogenomic databases

HOGENOMi HOG000223042.
KOi K14260.
OMAi ENELIIF.
OrthoDBi EOG6X9MJ6.

Enzyme and pathway databases

BioCyci SPYO160490:GJ81-1467-MONOMER.
SPYO293653:GHFC-1585-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
Pfami PF00155. Aminotran_1_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SF370Imported.
  2. "Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
    Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
    J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-947 / MGAS5005 / Serotype M1Imported and MGAS5005Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MGAS5005.
  4. "Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences."
    Nasser W., Beres S.B., Olsen R.J., Dean M.A., Rice K.A., Long S.W., Kristinsson K.G., Gottfredsson M., Vuopio J., Raisanen K., Cauget D., Steinbakk M., Lowe D.E., McGeere A., Darenberg J., Henriques-Normark B., van Benedeng C.A., Hoffmann S., Mussera J.M.
    Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2014)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SF370.

Entry informationi

Entry nameiQ99YB6_STRP1
AccessioniPrimary (citable) accession number: Q99YB6
Secondary accession number(s): Q48WZ4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3