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Q99YB6

- Q99YB6_STRP1

UniProt

Q99YB6 - Q99YB6_STRP1

Protein
Submitted name:

Aspartate aminotransferase

Gene

M5005_Spy1513

Organism
Streptococcus pyogenes serotype M1
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
    2. L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
    3. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    AminotransferaseImported, Transferase

    Enzyme and pathway databases

    BioCyciSPYO160490:GJ81-1467-MONOMER.
    SPYO293653:GHFC-1585-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Aspartate aminotransferaseImported (EC:2.6.1.1Imported)
    Submitted name:
    Putative aminotransferaseImported (EC:2.6.1.-Imported)
    Gene namesi
    Ordered Locus Names:M5005_Spy1513Imported, SPy_1779Imported
    OrganismiStreptococcus pyogenes serotype M1Imported
    Taxonomic identifieri301447 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002702: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliQ99YB6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000223042.
    KOiK14260.
    OMAiENELIIF.
    OrthoDBiEOG6X9MJ6.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR004839. Aminotransferase_I/II.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PfamiPF00155. Aminotran_1_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q99YB6-1 [UniParc]FASTAAdd to Basket

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    MKIIEKSSKL EHVAYDIRGP VLDEANRMIA SGEKILRLNT GNPAAFGFEA    50
    PDEVIRDLIV NARLSEGYSD SKGIFSARKA IMQYCQLKGF PDVDIEDIYL 100
    GNGVSELISI SLQALLDNGD EVLVPMPDYP LWTACVSLGG GKAVHYLCDE 150
    EAGWYPDIAD IKSKITSRTK AIVVINPNNP TGALYPKEIL EDIVALAREH 200
    QLIIFADEIY DRLVMDGKEH IAIASLAPDV FCVSMNGLSK SHRIAGFRVG 250
    WMVLSGPKDH VKGYIEGLNM LANMRLCSNV LAQQVVQTSL GGHQSVDALL 300
    LPGGRIFEQR NFIYEAINAI PGLSAVKPEA GLYLFPKIDR QMYRIDDDEE 350
    FVLQLLKQEK VMLVHGRGFN WKDPDHFRIV YLPSVEELED VQEKITRVLY 400
    QYRR 404
    Length:404
    Mass (Da):45,223
    Last modified:June 1, 2001 - v1
    Checksum:i30D9D2499183A217
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004092 Genomic DNA. Translation: AAK34514.1.
    CP000017 Genomic DNA. Translation: AAZ52131.1.
    RefSeqiNP_269793.1. NC_002737.1.
    YP_282876.1. NC_007297.1.

    Genome annotation databases

    EnsemblBacteriaiAAK34514; AAK34514; SPy_1779.
    AAZ52131; AAZ52131; M5005_Spy1513.
    GeneIDi3571397.
    902010.
    KEGGispy:SPy_1779.
    spz:M5005_Spy_1513.
    PATRICi19716992. VBIStrPyo79812_1547.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004092 Genomic DNA. Translation: AAK34514.1 .
    CP000017 Genomic DNA. Translation: AAZ52131.1 .
    RefSeqi NP_269793.1. NC_002737.1.
    YP_282876.1. NC_007297.1.

    3D structure databases

    ProteinModelPortali Q99YB6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK34514 ; AAK34514 ; SPy_1779 .
    AAZ52131 ; AAZ52131 ; M5005_Spy1513 .
    GeneIDi 3571397.
    902010.
    KEGGi spy:SPy_1779.
    spz:M5005_Spy_1513.
    PATRICi 19716992. VBIStrPyo79812_1547.

    Phylogenomic databases

    HOGENOMi HOG000223042.
    KOi K14260.
    OMAi ENELIIF.
    OrthoDBi EOG6X9MJ6.

    Enzyme and pathway databases

    BioCyci SPYO160490:GJ81-1467-MONOMER.
    SPYO293653:GHFC-1585-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR004839. Aminotransferase_I/II.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    Pfami PF00155. Aminotran_1_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SF370Imported.
    2. "Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events."
      Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.
      J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-947 / MGAS5005 / Serotype M1Imported and MGAS5005Imported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MGAS5005.
    4. "Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences."
      Nasser W., Beres S.B., Olsen R.J., Dean M.A., Rice K.A., Long S.W., Kristinsson K.G., Gottfredsson M., Vuopio J., Raisanen K., Cauget D., Steinbakk M., Lowe D.E., McGeere A., Darenberg J., Henriques-Normark B., van Benedeng C.A., Hoffmann S., Mussera J.M.
      Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2014)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: SF370.

    Entry informationi

    Entry nameiQ99YB6_STRP1
    AccessioniPrimary (citable) accession number: Q99YB6
    Secondary accession number(s): Q48WZ4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3