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Protein

Putative aldehyde dehydrogenase AldA

Gene

aldA

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei256By similarity1
Active sitei290By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi212 – 218NADBy similarity7

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase AldA (EC:1.2.1.3)
Gene namesi
Name:aldA
Ordered Locus Names:SAV0167
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000564561 – 495Putative aldehyde dehydrogenase AldAAdd BLAST495

Proteomic databases

PaxDbiQ99X54

2D gel databases

World-2DPAGE0002:Q99X54

Interactioni

Protein-protein interaction databases

STRINGi158878.SAV0167

Structurei

3D structure databases

ProteinModelPortaliQ99X54
SMRiQ99X54
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiENOG4105C26 Bacteria
COG1012 LUCA
HOGENOMiHOG000271505
KOiK00128
OMAiTFVQEDV
PhylomeDBiQ99X54

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00070 ALDEHYDE_DEHYDR_CYS, 1 hit
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

Q99X54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVNVRDYIA ENYGLFINGE FVKGSSDETI EVTNPATGET LSHITRAKDK
60 70 80 90 100
DVDHAVKVAQ EAFESWSLTS KSERAQMLRD IGDKLMAQKD KIAMIETLNN
110 120 130 140 150
GKPIRETTAI DIPFAARHFH YFASVIETEE GTVNDIDKDT MSIVRHEPIG
160 170 180 190 200
VVGAVVAWNF PMLLAAWKIA PAIAAGNTIV IQPSSSTPLS LLEVAKIFQE
210 220 230 240 250
VLPKGVVNIL TGKGSESGNA IFNHDGVDKL SFTGSTDVGY QVAEAAAKHL
260 270 280 290 300
VPATLELGGK SANIILDDAN LDLAVEGIQL GILFNQGEVC SAGSRLLVHE
310 320 330 340 350
KIYDQLVPRL QEAFSNIKVG DPQDEATQMG SQTGKDQLDK IQSYIDAAKE
360 370 380 390 400
SDAQILAGGH RLTENGLDKG FFFEPTLIAV PDNHHKLAQE EIFGPVLTVI
410 420 430 440 450
KVKDDQEAID IANDSEYGLA GGVFSQNITR ALNIAKAVRT GRIWINTYNQ
460 470 480 490
VPEGAPFGGY KKSGIGRETY KGALSNYQQV KNIYIDTSNA LKGLY
Length:495
Mass (Da):53,660
Last modified:June 1, 2001 - v1
Checksum:i36B448F85BFECD02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB56329.1
RefSeqiWP_000290397.1, NC_002758.2

Genome annotation databases

EnsemblBacteriaiBAB56329; BAB56329; SAV0167
KEGGisav:SAV0167

Similar proteinsi

Entry informationi

Entry nameiALDA_STAAM
AccessioniPrimary (citable) accession number: Q99X54
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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