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Q99X42

- Q99X42_STAAM

UniProt

Q99X42 - Q99X42_STAAM

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Protein
Submitted name:

Similar to surfactin synthetase

Gene

SAV0179

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. catalytic activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSAUR158878:GJJ5-179-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Similar to surfactin synthetaseImported
Gene namesi
Ordered Locus Names:SAV0179Imported
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)Imported
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000002481: Chromosome

PTM / Processingi

Keywords - PTMi

PhosphopantetheineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi158878.SAV0179.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F6CX-ray2.81A/B2010-2391[»]
4F6LX-ray3.86A/B1929-2391[»]
ProteinModelPortaliQ99X42.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3320.
HOGENOMiHOG000279727.
OMAiDADSNPK.
OrthoDBiEOG6XHC08.
PhylomeDBiQ99X42.

Family and domain databases

Gene3Di1.10.1200.10. 2 hits.
3.40.50.720. 1 hit.
InterProiIPR010071. AA_adenyl_domain.
IPR009081. Acyl_carrier_prot-like.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR013120. Male_sterile_NAD-bd.
IPR016040. NAD(P)-bd_dom.
IPR006162. PPantetheine_attach_site.
IPR010080. Thioester_reductase-like_dom.
[Graphical view]
PfamiPF00501. AMP-binding. 2 hits.
PF13193. AMP-binding_C. 2 hits.
PF00668. Condensation. 2 hits.
PF07993. NAD_binding_4. 1 hit.
PF00550. PP-binding. 2 hits.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 2 hits.
TIGRFAMsiTIGR01733. AA-adenyl-dom. 2 hits.
TIGR01746. Thioester-redct. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 2 hits.
PS00455. AMP_BINDING. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99X42-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIMGNLRFQQ EYFRIYKNNT ESTTHRNAYW VKLAKNVEAT KMMYALSTIV
60 70 80 90 100
QQHASIRHFF DVTTDDNLTM ILHEFLPFIE IKQVPSSSAN YDLEAFFKQE
110 120 130 140 150
LSTYHFNDSP LFKVKLFQFA DAAYILLDFH VSIFDDSQID IFLDDLCNAY
160 170 180 190 200
RGNTVINNTR QHAHINRNDD KDNQDASHIA LDSNYFRLEN NSDIHIDSYF
210 220 230 240 250
PIKHPFEQAL YQTYLIDDMT SIDMASLAVS VYLANHIMSQ QHDVTLGIHV
260 270 280 290 300
PSHLPNDLHG NIVPLTLTID AKDVCQRFTT DFNKCVLQNM SQLQCAKSSL
310 320 330 340 350
SLETIFHCYH HMMSCCNDVI EDVHQIHDAH TSLADIEIFP HQHGFKIIYN
360 370 380 390 400
SAAYDLLSIE TLSDLVRNIY LQITEENGNK RTTVDELNLM TERDIQLYDD
410 420 430 440 450
INLSLPEIDD AQTVVTLFEQ QVEATPNHVA VQFDGVFITY QTLNARANDL
460 470 480 490 500
AHRLRNQYGV EPNDRVAVIA EKSIEMIIAM IGVLKAGGAY VPIDPNYPSD
510 520 530 540 550
RQEYILKDAT PKVVITYQAL YENGKQNINH IDLNKIAWKN IDNLSKCNTL
560 570 580 590 600
EDHAYVIYTS GTTGNPKGTL IPHRGIVRLV HRNHYVPLNE ETTILLSGTI
610 620 630 640 650
AFDAATFEIY GALLNGGKLI VAKKEQLLNP IAVEQLINEN DVNTMWLTSS
660 670 680 690 700
LFNQIASERI EVLVPLKYLL IGGEVLNAKW VDLLNQKPKH PQIINGYGPT
710 720 730 740 750
ENTTFTTTYN IPNKVPNRIP IGKPILGTHV YIMQGERRCG VGIPGELCTS
760 770 780 790 800
GFGLAAGYLN QPELTADKFI KDSNINQLMY RSGDIVRLLP DGNIDYLYRK
810 820 830 840 850
DKQVKIRGFR IELSEVEHAL ERIQGINKAV VIVQNHDQDQ YIVAYYEAMH
860 870 880 890 900
TLSHNKIKSQ LRMTLPEYMI PVNFMHIEQI PITINGKLDK KALPIMDYVD
910 920 930 940 950
TDAYVAPSTD TEHLLCQIFA DILHVNQVGI HDNFFELGGH SLKATLVVNR
960 970 980 990 1000
IEASTGKRLQ IGDLLQKPTV FELAQAIAKV QEQNYEVIPE AIVKDDYVLS
1010 1020 1030 1040 1050
SAQKRMYLLW KSNHKDTVYN VPFLWRLSSG LNVAQLQQAV QHLIARHEIL
1060 1070 1080 1090 1100
RTQYIVVDDE VRQRIVADVV ADFEEVNTHF TDEQEIMRQF VAPFNLEKPS
1110 1120 1130 1140 1150
QIRVRYIRSP LHAYLFIDTH HIINDGMSNI QLMNDLNALY QHKLLLPLKL
1160 1170 1180 1190 1200
QYKDYSEWMS HRDMTKHRQY WLSQFKDEVP ILSLPTDYVR PNIKTTNGAM
1210 1220 1230 1240 1250
MSFTMNQQMR QLLQKYVEKH QITDFMFFMS VVMTLLSRYA RKDDVVVGSV
1260 1270 1280 1290 1300
MSARMHKGTE QMLGMFANTL VYRGQPSPDK MWTQFLQEVK EMSLEAYEHQ
1310 1320 1330 1340 1350
EYPFECLVND LDQSHDASRN PLFDVMLVLQ NNETNHAHFG HSKLTHIQPK
1360 1370 1380 1390 1400
SVTAKFDLSF IIEEDRDDYT INIEYNTDLY HSETVRHMGN QCMIMIDYIL
1410 1420 1430 1440 1450
KHQDTLQICD IPNGTEELLN WVNTHVNDRM LNVPGNKSII SYFNEVVSRQ
1460 1470 1480 1490 1500
GNHVALVMND LTMTYETLRN YVDAIAHMLL SNGVGNGQRV ALFTERSFEM
1510 1520 1530 1540 1550
IAAMLATVKV GASYIPIDID FPNKRQGAIL EDAKVTAVMS YGVEIETTLP
1560 1570 1580 1590 1600
VIQLENAKGF VESKENEQYD DLHGNQLENT AMLDNEMYAI YTSGTTGMPK
1610 1620 1630 1640 1650
GVAIRQRNLL NLVHAWSTEL QLGDNEVFLQ HANIVFDASV MEIYCCLLNG
1660 1670 1680 1690 1700
HTLVIPDREE RVNPEQLQQL INKHRVTVAS IPLQMCSIME DFYIEKLITG
1710 1720 1730 1740 1750
GATSTASFVK YIEKHCGTYF NAYGPSESTV ITSYWSHHCG DLIPETIPIG
1760 1770 1780 1790 1800
KPLSNIQVYI MSDGLLCGIG MPGELCIAGD SLAIGYINRP ELMADKWQNN
1810 1820 1830 1840 1850
PFGKGKLYHS GDLARYTSDG QIEFLGRIDK QVKVNGYRIE LDEIENVILA
1860 1870 1880 1890 1900
IRGISDCVVT VSHFDTHDIL NAYYVGEQQV EQDLKQYLND QLPKYMIPKT
1910 1920 1930 1940 1950
ITHIDCMPLT TNDKVDTTRL PNPSPIQQSN KVYSEPSNEI EQTFVDVFGE
1960 1970 1980 1990 2000
VLKQNDVGVD DDFFELGGNS LEAMLVVSHL KRFGHHISMQ TLYQYKTVRQ
2010 2020 2030 2040 2050
IVNYMYQNQQ SLVALPDNLS ELQKIVMSRY NLGILEDSLS HRPLGNTLLT
2060 2070 2080 2090 2100
GATGFLGAYL IEALQGYSHR IYCFIRADNE EIAWYKLMTN LNDYFSEETV
2110 2120 2130 2140 2150
EMMLSNIEVI VGDFECMDDV VLPENMDTII HAGARTDHFG DDDEFEKVNV
2160 2170 2180 2190 2200
QGTVDVIRLA QQHHARLIYV STISVGTYFD IDTEDVTFSE ADVYKGQLLT
2210 2220 2230 2240 2250
SPYTRSKFYS ELKVLEAVNN GLDGRIVRVG NLTSPYNGRW HMRNIKTNRF
2260 2270 2280 2290 2300
SMVMNDLLQL DCIGVSMAEM PVDFSFVDTT ARQIVALAQV NTPQIIYHVL
2310 2320 2330 2340 2350
SPNKMPVKSL LECVKRKEIE LVSDESFNEI LQKQDMYETI GLTSVDREQQ
2360 2370 2380 2390
LAMIDTTLTL KIMNHISEKW PTITNNWLYH WAQYIKTIFN K
Length:2,391
Mass (Da):273,338
Last modified:June 1, 2001 - v1
Checksum:i13A3A2C5D9298AC1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000017 Genomic DNA. Translation: BAB56341.1.
PIRiG89779.
RefSeqiNP_370703.1. NC_002758.2.

Genome annotation databases

EnsemblBacteriaiBAB56341; BAB56341; SAV0179.
GeneIDi1120138.
KEGGisav:SAV0179.
PATRICi19560965. VBIStaAur52173_0180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000017 Genomic DNA. Translation: BAB56341.1 .
PIRi G89779.
RefSeqi NP_370703.1. NC_002758.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4F6C X-ray 2.81 A/B 2010-2391 [» ]
4F6L X-ray 3.86 A/B 1929-2391 [» ]
ProteinModelPortali Q99X42.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 158878.SAV0179.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB56341 ; BAB56341 ; SAV0179 .
GeneIDi 1120138.
KEGGi sav:SAV0179.
PATRICi 19560965. VBIStaAur52173_0180.

Phylogenomic databases

eggNOGi COG3320.
HOGENOMi HOG000279727.
OMAi DADSNPK.
OrthoDBi EOG6XHC08.
PhylomeDBi Q99X42.

Enzyme and pathway databases

BioCyci SAUR158878:GJJ5-179-MONOMER.

Family and domain databases

Gene3Di 1.10.1200.10. 2 hits.
3.40.50.720. 1 hit.
InterProi IPR010071. AA_adenyl_domain.
IPR009081. Acyl_carrier_prot-like.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR013120. Male_sterile_NAD-bd.
IPR016040. NAD(P)-bd_dom.
IPR006162. PPantetheine_attach_site.
IPR010080. Thioester_reductase-like_dom.
[Graphical view ]
Pfami PF00501. AMP-binding. 2 hits.
PF13193. AMP-binding_C. 2 hits.
PF00668. Condensation. 2 hits.
PF07993. NAD_binding_4. 1 hit.
PF00550. PP-binding. 2 hits.
[Graphical view ]
SUPFAMi SSF47336. SSF47336. 2 hits.
TIGRFAMsi TIGR01733. AA-adenyl-dom. 2 hits.
TIGR01746. Thioester-redct. 1 hit.
PROSITEi PS50075. ACP_DOMAIN. 2 hits.
PS00455. AMP_BINDING. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Mu50 / ATCC 700699Imported.
  2. "Heterologous expression and structural characterisation of a pyrazinone natural product assembly line."
    Wyatt M.A., Mok M.C., Junop M., Magarvey N.A.
    ChemBioChem 13:2408-2415(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.81 ANGSTROMS) OF 2010-2391.

Entry informationi

Entry nameiQ99X42_STAAM
AccessioniPrimary (citable) accession number: Q99X42
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 1, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteomeImported

External Data

Dasty 3