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Protein

Uncharacterized response regulatory protein SAV0223

Gene

SAV0223

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probable member of the two-component regulatory system SAV0224/SAV0223.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi170 – 191H-T-H motifPROSITE-ProRule annotationAdd BLAST22
DNA bindingi217 – 240H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation, Two-component regulatory system

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSAUR158878:GJJ5-223-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized response regulatory protein SAV0223
Gene namesi
Ordered Locus Names:SAV0223
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002991121 – 252Uncharacterized response regulatory protein SAV0223Add BLAST252

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei554-aspartylphosphatePROSITE-ProRule annotation1

Post-translational modificationi

Phosphorylated by SAV0224.Curated

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ99X00.

Interactioni

Protein-protein interaction databases

STRINGi158878.SAV0223.

Structurei

3D structure databases

ProteinModelPortaliQ99X00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 118Response regulatoryPROSITE-ProRule annotationAdd BLAST116
Domaini153 – 250HTH araC/xylS-typePROSITE-ProRule annotationAdd BLAST98

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 response regulatory domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107VQW. Bacteria.
COG4753. LUCA.
HOGENOMiHOG000059795.
KOiK07720.
OMAiDHITHIR.
PhylomeDBiQ99X00.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR011006. CheY-like_superfamily.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52172. SSF52172. 1 hit.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99X00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKVVICDDE RIIREGLKQI IPWGDYHFNT IYTAKDGVEA LSLIQQHQPE
60 70 80 90 100
LVITDIRMPR KNGVDLLNDI ALLDCNVIIL SSYDDFEYMK AGIQHHVLDY
110 120 130 140 150
LLKPVDHAQL EVILGRLVRT LLEQQSQNGR SLASCHDAFQ PLLKVEYDDY
160 170 180 190 200
YVNQIVDQIK QSYQTKVTVS DLIQHIDVSE SYAMRTFKDH VGITIVDYLN
210 220 230 240 250
RYRILQSLQL LDRHYKHYEI ADKVGFSEYK MFSYHFKKYL QMSPSDYCKQ

AK
Length:252
Mass (Da):29,575
Last modified:June 1, 2001 - v1
Checksum:i16E88E45A3D52E2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA. Translation: BAB56385.1.
RefSeqiWP_000477526.1. NC_002758.2.

Genome annotation databases

EnsemblBacteriaiBAB56385; BAB56385; SAV0223.
KEGGisav:SAV0223.
PATRICi19561056. VBIStaAur52173_0225.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA. Translation: BAB56385.1.
RefSeqiWP_000477526.1. NC_002758.2.

3D structure databases

ProteinModelPortaliQ99X00.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi158878.SAV0223.

Proteomic databases

PaxDbiQ99X00.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB56385; BAB56385; SAV0223.
KEGGisav:SAV0223.
PATRICi19561056. VBIStaAur52173_0225.

Phylogenomic databases

eggNOGiENOG4107VQW. Bacteria.
COG4753. LUCA.
HOGENOMiHOG000059795.
KOiK07720.
OMAiDHITHIR.
PhylomeDBiQ99X00.

Enzyme and pathway databases

BioCyciSAUR158878:GJJ5-223-MONOMER.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR011006. CheY-like_superfamily.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52172. SSF52172. 1 hit.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY223_STAAM
AccessioniPrimary (citable) accession number: Q99X00
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.