Q99WW4 (SCDA_STAAM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Iron-sulfur cluster repair protein ScdA

Gene names

Name:	scdA
Ordered Locus Names:	SAV0259

Organism

Staphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP]

Taxonomic identifier

158878 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions By similarity. HAMAP MF_01156
Subunit structure	Homodimer By similarity. HAMAP MF_01156
Subcellular location	Cytoplasm Potential HAMAP MF_01156.
Sequence similarities	Belongs to the RIC family. ScdA subfamily.

Ontologies

Keywords
Biological process	Stress response
Cellular component	Cytoplasm
Ligand	Iron Metal-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 224	224	Iron-sulfur cluster repair protein ScdA HAMAP MF_01156		PRO_0000220336

Sequences

	Sequence		Length	Mass (Da)
	Q99WW4 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 056F55A750C2C712	FASTA	224	25,468
	10 20 30 40 50 60 MINKNDIVAD IVIDYPKAAD IFRSVGIDFC CGGQVSIEAA SLEKKNVDLN ELLQRLNDVE 70 80 90 100 110 120 QTNTPGSLNP KFLNVSSLIQ YIQAAYHEPL REEFKNLTPY VTKLSKVHGP NHPYLVELKE 130 140 150 160 170 180 TYDTFKSGML EHMQKEDDVD FPKLIKYEQG EVVNDINTVI DDLVSDHIAT GQLLVKMSDL 190 200 210 220 TSSYEPPIEA CGTWRLVYQR LKALEVLTHE HVHLENHVLF KKVS

References

[1]

"Whole genome sequencing of meticillin-resistant Staphylococcus aureus." Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y. , Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H., Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K., Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H., Hiramatsu K. Lancet 357:1225-1240(2001) [PubMed: 11418146] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mu50 / ATCC 700699.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000017 Genomic DNA. Translation: BAB56421.1.
RefSeq	NP_370783.1. NC_002758.2.
3D structure databases
ProteinModelPortal	Q99WW4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q99WW4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000007529; EBSTAP00000007347; EBSTAG00000007528.
GeneID	1120217.
GenomeReviews	Gene locus SAV0259 in contig BA000017_GR.
KEGG	sav:SAV0259.
PATRIC	19561132. VBIStaAur52173_0263.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2846.
GeneTree	EBGT00050000025196.
HOGENOM	HBG308681.
OMA	GNPINAM.
PhylomeDB	Q99WW4.
ProtClustDB	PRK13276.
Enzyme and pathway databases
BioCyc	SAUR158878:SAV0259-MONOMER.
Family and domain databases
HAMAP	MF_01156. RIC_ScdA. [Tree]
InterPro	IPR007500. DUF542_ScdA_N. IPR012312. Haemerythrin/HHE_cat-bd_motif. IPR019903. RIC_family. IPR023551. RIC_family_ScdA. [Graphical view]
KO	K07322.
Pfam	PF01814. Hemerythrin. 2 hits. PF04405. ScdA_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR03652. FeS_repair_RIC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SCDA_STAAM

Accession

Primary (citable) accession number: Q99WW4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	June 1, 2001
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program