Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-binding protein HU

Gene

hup

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA condensation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-binding protein HU
Gene namesi
Name:hup
Ordered Locus Names:SAV1473
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002233761 – 90DNA-binding protein HUAdd BLAST90

Proteomic databases

PaxDbiQ99U17
PRIDEiQ99U17

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi158878.SAV1473

Structurei

Secondary structure

190
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 13Combined sources11
Helixi18 – 37Combined sources20
Beta strandi42 – 44Combined sources3
Turni45 – 47Combined sources3
Beta strandi48 – 55Combined sources8
Beta strandi58 – 61Combined sources4
Turni63 – 65Combined sources3
Beta strandi68 – 71Combined sources4
Beta strandi74 – 81Combined sources8
Helixi83 – 89Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4QJNX-ray2.61A/B/C/D1-90[»]
4QJUX-ray2.16A/B1-90[»]
ProteinModelPortaliQ99U17
SMRiQ99U17
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105K70 Bacteria
COG0776 LUCA
HOGENOMiHOG000043829
KOiK03530
OMAiRSNATKA
PhylomeDBiQ99U17

Family and domain databases

Gene3Di4.10.520.10, 1 hit
InterProiView protein in InterPro
IPR000119 Hist_DNA-bd
IPR020816 Histone-like_DNA-bd_CS
IPR010992 IHF-like_DNA-bd_dom_sf
PANTHERiPTHR33175 PTHR33175, 1 hit
PfamiView protein in Pfam
PF00216 Bac_DNA_binding, 1 hit
PRINTSiPR01727 DNABINDINGHU
SMARTiView protein in SMART
SM00411 BHL, 1 hit
SUPFAMiSSF47729 SSF47729, 1 hit
PROSITEiView protein in PROSITE
PS00045 HISTONE_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q99U17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKTDLINAV AEQADLTKKE AGSAVDAVFE SIQNSLAKGE KVQLIGFGNF
60 70 80 90
EVRERAARKG RNPQTGKEID IPASKVPAFK AGKALKDAVK
Length:90
Mass (Da):9,626
Last modified:June 1, 2001 - v1
Checksum:i554F2EF88514060F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB57635.1
RefSeqiWP_001043863.1, NC_002758.2

Genome annotation databases

EnsemblBacteriaiBAB57635; BAB57635; SAV1473
GeneIDi14478799
KEGGisav:SAV1473

Similar proteinsi

Entry informationi

Entry nameiDBH_STAAM
AccessioniPrimary (citable) accession number: Q99U17
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health