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Q99SE3 (PTPB_STAAM) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Low molecular weight protein-tyrosine-phosphatase PtpB

EC=3.1.3.48
Alternative name(s):
Phosphotyrosine phosphatase B
Short name=PTPase B
Gene names
Name:ptpB
Ordered Locus Names:SAV2115
OrganismStaphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP]
Taxonomic identifier158878 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length139 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Dephosphorylates the phosphotyrosine-containing proteins By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 139139Low molecular weight protein-tyrosine-phosphatase PtpB
PRO_0000300675

Sites

Active site71Nucleophile By similarity
Active site131 By similarity
Active site1111Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q99SE3 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 63EB2C0E2A53EA5B

FASTA13915,788
        10         20         30         40         50         60 
MKILFVCTGN TCRSPLAESI AKEVMPNHQF ESRGIFAVNN QGVSNYVEDL VEEHHLAETT 

        70         80         90        100        110        120 
LSQQFTEADL KADIILTMSY SHKELIEAHF GLQNHVFTLH EYVKEAGEVI DPYGGTKEMY 

       130 
VHTYEELVSL ILKLKDIIC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000017 Genomic DNA. Translation: BAB58277.1.
RefSeqNP_372639.1. NC_002758.2.

3D structure databases

ProteinModelPortalQ99SE3.
SMRQ99SE3. Positions 1-134.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING158878.SAV2115.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB58277; BAB58277; SAV2115.
GeneID1122131.
KEGGsav:SAV2115.
PATRIC19565108. VBIStaAur52173_2189.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0394.
HOGENOMHOG000273091.
KOK01104.
OMAPMAMALL.
OrthoDBEOG6MH5JB.
ProtClustDBCLSK885771.

Enzyme and pathway databases

BioCycSAUR158878:GJJ5-2174-MONOMER.

Family and domain databases

InterProIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
[Graphical view]
PfamPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSPR00719. LMWPTPASE.
SMARTSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMSSF52788. SSF52788. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTPB_STAAM
AccessionPrimary (citable) accession number: Q99SE3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families