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Q99RQ5 (FENR_STAAM) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase

Short name=FNR
Short name=Fd-NADP(+) reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:SAV2372
OrganismStaphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP]
Taxonomic identifier158878 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP-Rule MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP-Rule MF_01685

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Sequence caution

The sequence BAB58534.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionNADP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

ferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 344344Ferredoxin--NADP reductase HAMAP-Rule MF_01685
PRO_0000364941

Sites

Binding site121FAD By similarity
Binding site311FAD By similarity
Binding site391FAD By similarity
Binding site431FAD By similarity
Binding site831FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1181FAD; via amide nitrogen By similarity
Binding site2851FAD By similarity
Binding site3261FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q99RQ5 [UniParc].

Last modified March 3, 2009. Version 2.
Checksum: 46E1A319359751D3

FASTA34438,230
        10         20         30         40         50         60 
MKDVTIIGGG PSGLYASFYA GLRDMSVRLI DVQSELGGKM RIYPEKIIWD IGGIAPKPCH 

        70         80         90        100        110        120 
EILKDTIKQG LYFKPEVHLN ERVVDIRKKA ERHFEVETEA GEIYTSKAVI IAIGAGIINP 

       130        140        150        160        170        180 
KQLDVKGVER YQLTNLHYVV QSYRRFKDKD VLISGGGNTA LDWAHDIAKI AKSVTVVYRK 

       190        200        210        220        230        240 
EDVSGHEAMK TLVTDLNVKL CPKTRIKYLV GNDDETHISE VVLEHVESGD RHTVKFDDVI 

       250        260        270        280        290        300 
ISHGFDRCNT LLSETSSKLD MHDDCRVKGF GNTTTSIPGI YACGDIVYHD AKSHLIASAF 

       310        320        330        340 
SDGANAANLA KTYIQPDANA EGYVSSHHEV FKEANKTIVN KHLY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000017 Genomic DNA. Translation: BAB58534.1. Different initiation.
RefSeqNP_372896.1. NC_002758.2.

3D structure databases

ProteinModelPortalQ99RQ5.
SMRQ99RQ5. Positions 1-321.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING158878.SAV2372.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB58534; BAB58534; SAV2372.
GeneID1122397.
KEGGsav:SAV2372.
PATRIC19565658. VBIStaAur52173_2455.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHOG000072909.
KOK00384.
OMAVEGRAWI.
OrthoDBEOG661H9M.
ProtClustDBCLSK885935.

Enzyme and pathway databases

BioCycSAUR158878:GJJ5-2440-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_STAAM
AccessionPrimary (citable) accession number: Q99RQ5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 3, 2009
Last modified: March 19, 2014
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families