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Q99RQ5

- FENR_STAAM

UniProt

Q99RQ5 - FENR_STAAM

Protein

Ferredoxin--NADP reductase

Gene

SAV2372

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 2 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.UniRule annotation

    Cofactori

    Binds 1 FAD per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei12 – 121FADUniRule annotation
    Binding sitei31 – 311FADUniRule annotation
    Binding sitei39 – 391FADUniRule annotation
    Binding sitei43 – 431FADUniRule annotation
    Binding sitei83 – 831FAD; via amide nitrogen and carbonyl oxygenUniRule annotation
    Binding sitei118 – 1181FAD; via amide nitrogenUniRule annotation
    Binding sitei285 – 2851FADUniRule annotation
    Binding sitei326 – 3261FADUniRule annotation

    GO - Molecular functioni

    1. ferredoxin-NADP+ reductase activity Source: UniProtKB-HAMAP
    2. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP
    3. NADP binding Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    FAD, Flavoprotein, NADP

    Enzyme and pathway databases

    BioCyciSAUR158878:GJJ5-2440-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ferredoxin--NADP reductaseUniRule annotation (EC:1.18.1.2UniRule annotation)
    Short name:
    FNRUniRule annotation
    Short name:
    Fd-NADP(+) reductaseUniRule annotation
    Gene namesi
    Ordered Locus Names:SAV2372
    OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
    Taxonomic identifieri158878 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000002481: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 344344Ferredoxin--NADP reductasePRO_0000364941Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi158878.SAV2372.

    Structurei

    3D structure databases

    ProteinModelPortaliQ99RQ5.
    SMRiQ99RQ5. Positions 3-321.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ferredoxin--NADP reductase type 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0492.
    HOGENOMiHOG000072909.
    KOiK00384.
    OMAiYTAGMVQ.
    OrthoDBiEOG661H9M.

    Family and domain databases

    HAMAPiMF_01685. FENR2.
    InterProiIPR013027. FAD_pyr_nucl-diS_OxRdtase.
    IPR022890. Fd--NADP_Rdtase_type_2.
    IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
    IPR001327. Pyr_OxRdtase_NAD-bd_dom.
    IPR000103. Pyridine_nuc-diS_OxRdtase_2.
    [Graphical view]
    PfamiPF00070. Pyr_redox. 1 hit.
    PF07992. Pyr_redox_2. 1 hit.
    [Graphical view]
    PRINTSiPR00368. FADPNR.
    PR00469. PNDRDTASEII.

    Sequencei

    Sequence statusi: Complete.

    Q99RQ5-1 [UniParc]FASTAAdd to Basket

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    MKDVTIIGGG PSGLYASFYA GLRDMSVRLI DVQSELGGKM RIYPEKIIWD    50
    IGGIAPKPCH EILKDTIKQG LYFKPEVHLN ERVVDIRKKA ERHFEVETEA 100
    GEIYTSKAVI IAIGAGIINP KQLDVKGVER YQLTNLHYVV QSYRRFKDKD 150
    VLISGGGNTA LDWAHDIAKI AKSVTVVYRK EDVSGHEAMK TLVTDLNVKL 200
    CPKTRIKYLV GNDDETHISE VVLEHVESGD RHTVKFDDVI ISHGFDRCNT 250
    LLSETSSKLD MHDDCRVKGF GNTTTSIPGI YACGDIVYHD AKSHLIASAF 300
    SDGANAANLA KTYIQPDANA EGYVSSHHEV FKEANKTIVN KHLY 344
    Length:344
    Mass (Da):38,230
    Last modified:March 3, 2009 - v2
    Checksum:i46E1A319359751D3
    GO

    Sequence cautioni

    The sequence BAB58534.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000017 Genomic DNA. Translation: BAB58534.1. Different initiation.
    RefSeqiNP_372896.1. NC_002758.2.

    Genome annotation databases

    EnsemblBacteriaiBAB58534; BAB58534; SAV2372.
    GeneIDi1122397.
    KEGGisav:SAV2372.
    PATRICi19565658. VBIStaAur52173_2455.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000017 Genomic DNA. Translation: BAB58534.1 . Different initiation.
    RefSeqi NP_372896.1. NC_002758.2.

    3D structure databases

    ProteinModelPortali Q99RQ5.
    SMRi Q99RQ5. Positions 3-321.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 158878.SAV2372.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB58534 ; BAB58534 ; SAV2372 .
    GeneIDi 1122397.
    KEGGi sav:SAV2372.
    PATRICi 19565658. VBIStaAur52173_2455.

    Phylogenomic databases

    eggNOGi COG0492.
    HOGENOMi HOG000072909.
    KOi K00384.
    OMAi YTAGMVQ.
    OrthoDBi EOG661H9M.

    Enzyme and pathway databases

    BioCyci SAUR158878:GJJ5-2440-MONOMER.

    Family and domain databases

    HAMAPi MF_01685. FENR2.
    InterProi IPR013027. FAD_pyr_nucl-diS_OxRdtase.
    IPR022890. Fd--NADP_Rdtase_type_2.
    IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
    IPR001327. Pyr_OxRdtase_NAD-bd_dom.
    IPR000103. Pyridine_nuc-diS_OxRdtase_2.
    [Graphical view ]
    Pfami PF00070. Pyr_redox. 1 hit.
    PF07992. Pyr_redox_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00368. FADPNR.
    PR00469. PNDRDTASEII.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Mu50 / ATCC 700699.

    Entry informationi

    Entry nameiFENR_STAAM
    AccessioniPrimary (citable) accession number: Q99RQ5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 88 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3