Q99R78 (Q99R78_STAAM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative D-specific D-2-hydroxyacid dehydrogenase EMBL BAB58721.1

Gene names

Ordered Locus Names:

SAV2559

Organism

Staphylococcus aureus (strain Mu50 / ATCC 700699) [Complete proteome] [HAMAP]

Taxonomic identifier

158878 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. RuleBase RU003719

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003720
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q99R78 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: CD2E1A3368206416	FASTA	332	37,173
	10 20 30 40 50 60 MTKIKIMSVR DEDMPYIKAW AEKHHVEVDI TKEALTDDNV EGVAGYDGLS LSQQIPLSEH 70 80 90 100 110 120 VYKRLNELGI KQIAQRSAGF DTYDLELANK YNLIVSNVPS YSPNSIAEFA VNQAINVVRH 130 140 150 160 170 180 FNQIQTKVRE HDFRWEPTIL SKSIKDLKVA VIGTGRIGRV VADIFANGYQ SDVVAYDPFP 190 200 210 220 230 240 NAKIATYVDY KDTIEEAVEG ADIVTLHVPA TKYNHYLFNA ELFKHFKKGA VFVNCARGSL 250 260 270 280 290 300 VDTKALLDAL DNGVIKGAAL DTYEFERKLF PSDQRGKTPN DPLLESLIDR EDVILTPHIA 310 320 330 FYTEAAVKNL IVDALDATLD VLQTGDTRLR VN

References

[1]

"Whole genome sequencing of meticillin-resistant Staphylococcus aureus." Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y. , Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H., Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K., Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H., Hiramatsu K. Lancet (Lond.) 357:1225-1240(2001) [PubMed: 11418146] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000017 Genomic DNA. Translation: BAB58721.1.
PIR	H90060.
RefSeq	NP_373083.1. NC_002758.2.
3D structure databases
HSSP	HSSP built from PDB template 1J49 based on UniProtKB P26297.
ProteinModelPortal	Q99R78.
ModBase	Search...
Protein-protein interaction databases
STRING	Q99R78.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000005745; EBSTAP00000005563; EBSTAG00000005744.
GeneID	1122584.
GenomeReviews	Gene locus SAV2559 in contig BA000017_GR.
KEGG	sav:SAV2559.
PATRIC	19566052. VBIStaAur52173_2652.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1052.
GeneTree	EBGT00050000024534.
HOGENOM	HBG731446.
OMA	EMVHQSF.
ProtClustDB	PRK08605.
Enzyme and pathway databases
BioCyc	SAUR158878:SAV2559-MONOMER.
Family and domain databases
InterPro	IPR006139. D-isomer_2_OHA_DH_cat_dom. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 2 hits.
KO	K03778.
Pfam	PF00389. 2-Hacid_dh. 1 hit. PF02826. 2-Hacid_dh_C. 1 hit. [Graphical view]
PROSITE	PS00065. D_2_HYDROXYACID_DH_1. 1 hit. PS00670. D_2_HYDROXYACID_DH_2. 1 hit. PS00671. D_2_HYDROXYACID_DH_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q99R78_STAAM

Accession

Primary (citable) accession number: Q99R78

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	December 14, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)