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Protein

Voltage-dependent calcium channel gamma subunit

Gene

Cacng2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Calcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotation

Keywords - Biological processi

Calcium transport, Ion transport, Transport

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Voltage-dependent calcium channel gamma subunitUniRule annotation
Gene namesi
Name:Cacng2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi71095. Cacng2.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3524HelicalUniRule annotationAdd
BLAST
Transmembranei106 – 12823HelicalUniRule annotationAdd
BLAST
Transmembranei135 – 15824HelicalUniRule annotationAdd
BLAST
Transmembranei178 – 20225HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ99PR9.
PRIDEiQ99PR9.

Expressioni

Gene expression databases

GenevisibleiQ99PR9. RN.

Interactioni

Subunit structurei

The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.UniRule annotation

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000008414.

Family & Domainsi

Sequence similaritiesi

Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFNQ. Eukaryota.
ENOG4110ISU. LUCA.
HOVERGENiHBG003682.
KOiK04867.
PhylomeDBiQ99PR9.

Family and domain databases

InterProiIPR004031. PMP22/EMP/MP20/Claudin.
IPR005422. VDCC_g2su.
IPR008368. VDCC_gsu.
[Graphical view]
PfamiPF00822. PMP22_Claudin. 1 hit.
[Graphical view]
PRINTSiPR01792. VDCCGAMMA.
PR01602. VDCCGAMMA2.

Sequencei

Sequence statusi: Complete.

Q99PR9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLFDRGVQM LLTTVGAFAA FSLMTIAVGT DYWLYSRGVC KTKSVSENET
60 70 80 90 100
SKKNEEVMTH SGLWRTCCLE GNFKGLCKQI DHFPEDADYE ADTAEYFLRA
110 120 130 140 150
VRASSIFPIL SVILLFMGGL CIAASEFYKT RHNIILSAGI FFVSAGLSNI
160 170 180 190 200
IGIIVYISAN AGDPSKSDSK KNSYSYGWSF YFGALSFIIA EMVGVLAVHM
210 220 230 240 250
FIDRHKQLRA TARATDYLQA SAITRIPSYR YRYQRRSRSS SRSTEPSHSR
260 270 280 290 300
DASPVGVKGF NTLPSTEISM YTLSRDPLKA ATTPIATYNS DRDNSFLQVH
310 320
NCIQKDSKDS LHANTANRRT TPV
Length:323
Mass (Da):35,907
Last modified:June 1, 2001 - v1
Checksum:iA224475606A0EB4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF118818 mRNA. Translation: AAK08653.1.
RefSeqiNP_445803.1. NM_053351.1.
UniGeneiRn.72939.

Genome annotation databases

GeneIDi84347.
KEGGirno:84347.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF118818 mRNA. Translation: AAK08653.1.
RefSeqiNP_445803.1. NM_053351.1.
UniGeneiRn.72939.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000008414.

Proteomic databases

PaxDbiQ99PR9.
PRIDEiQ99PR9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi84347.
KEGGirno:84347.

Organism-specific databases

CTDi10369.
RGDi71095. Cacng2.

Phylogenomic databases

eggNOGiENOG410IFNQ. Eukaryota.
ENOG4110ISU. LUCA.
HOVERGENiHBG003682.
KOiK04867.
PhylomeDBiQ99PR9.

Miscellaneous databases

NextBioi616643.

Gene expression databases

GenevisibleiQ99PR9. RN.

Family and domain databases

InterProiIPR004031. PMP22/EMP/MP20/Claudin.
IPR005422. VDCC_g2su.
IPR008368. VDCC_gsu.
[Graphical view]
PfamiPF00822. PMP22_Claudin. 1 hit.
[Graphical view]
PRINTSiPR01792. VDCCGAMMA.
PR01602. VDCCGAMMA2.
ProtoNetiSearch...

Publicationsi

  1. Ip F.C.F., Ip N.Y.
    Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ99PR9_RAT
AccessioniPrimary (citable) accession number: Q99PR9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 13, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.