Q99PF3 (Q99PF3_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
APEX EMBL AAG49922.1

Gene names

Name:	Apex1 RGD 2126
Synonyms:	Apex EMBL AAG49922.1

Organism

Rattus norvegicus (Rat) EMBL AAG49922.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	289 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	DNA demethylation Inferred from electronic annotation. Source: Compara DNA repair Inferred from electronic annotation. Source: InterPro cell redox homeostasis Inferred from electronic annotation. Source: Compara nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC positive regulation of DNA repair Inferred from electronic annotation. Source: Compara regulation of mRNA stability Inferred from electronic annotation. Source: Compara
Cellular_component	centrosome Inferred from electronic annotation. Source: Compara mitochondrion Inferred from electronic annotation. Source: Compara nuclear speck Inferred from electronic annotation. Source: Compara nucleolus Inferred from electronic annotation. Source: Compara nucleus Inferred from sequence or structural similarity. Source: UniProtKB perinuclear region of cytoplasm Inferred from sequence or structural similarity. Source: UniProtKB
Molecular_function	DNA binding Inferred from sequence or structural similarity. Source: UniProtKB DNA-(apurinic or apyrimidinic site) lyase activity Inferred from electronic annotation. Source: Compara chromatin DNA binding Inferred from electronic annotation. Source: Compara damaged DNA binding Inferred from electronic annotation. Source: Compara metal ion binding Inferred from sequence or structural similarity. Source: UniProtKB oxidoreductase activity Inferred from sequence or structural similarity. Source: UniProtKB phosphoric diester hydrolase activity Inferred from electronic annotation. Source: Compara site-specific endodeoxyribonuclease activity, specific for altered base Inferred from electronic annotation. Source: Compara transcription coactivator activity Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAG49922.1

Sequences

	Sequence		Length	Mass (Da)
	Q99PF3 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 67E82454D062CE51	FASTA	289	32,353
	10 20 30 40 50 60 KRAAAEDGEE PKSEPETKKS KGAAKKTEKE AAGEGPVLYE DPPDQKTSAS GKSATLKICS 70 80 90 100 110 120 WNVDGLRAWI KKKGLDWVKE EAPDILCLQE TKCSENKLPA ELQELPGLTH QYWSAPSDKE 130 140 150 160 170 180 GYSGVGLLSR QCPLKVSYGI AYVPNAGRGL VRLEYRQRWD EAFRKFLKDL ASRKPLVLCG 190 200 210 220 230 240 DLNVAHEEID LRNPKGNKKN AGFTPQERQG FGEMLQAVPL ADSFRHLYPN TAYAYTFWTY 250 260 270 280 MMNARSKNVG WRLDYFLLSH SLLPALCDSK IRSKALGSDH CPITLYLAL

References

[1]	Xie Z.H., Liu C.Z., He Y.H., Wang A.M., Ma C. Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Norway EMBL AAG49922.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF311054 mRNA. Translation: AAG49922.1.
IPI	IPI00200918.
UniGene	Rn.5949.
3D structure databases
HSSP	HSSP built from PDB template 1BIX based on UniProtKB P27695.
ProteinModelPortal	Q99PF3.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-4613115.
STRING	Q99PF3.
Proteomic databases
PRIDE	Q99PF3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
RGD	2126. Apex1.
Phylogenomic databases
HOVERGEN	HBG050531.
InParanoid	Q99PF3.
Gene expression databases
ArrayExpress	Q99PF3.
Genevestigator	Q99PF3.
Family and domain databases
InterPro	IPR020847. AP_endonuclease_F1_BS. IPR020848. AP_endonuclease_F1_CS. IPR005135. Endo/exonuclease/phosphatase. IPR004808. ExoDNase_III. [Graphical view]
PANTHER	PTHR22748. PTHR22748. 1 hit.
Pfam	PF03372. Exo_endo_phos. 1 hit. [Graphical view]
SUPFAM	SSF56219. Exo_endo_phos. 1 hit.
TIGRFAMs	TIGR00633. xth. 2 hits.
PROSITE	PS00726. AP_NUCLEASE_F1_1. 1 hit. PS00727. AP_NUCLEASE_F1_2. 1 hit. PS00728. AP_NUCLEASE_F1_3. 1 hit. PS51435. AP_NUCLEASE_F1_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q99PF3_RAT

Accession

Primary (citable) accession number: Q99PF3

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	April 3, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)