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Q99PF3 (Q99PF3_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Apex1 RGD 2126
Synonyms:Apex EMBL AAG49922.1
OrganismRattus norvegicus (Rat) EMBL AAG49922.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length289 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processDNA demethylation

Inferred from electronic annotation. Source: Ensembl

DNA repair

Inferred from electronic annotation. Source: InterPro

cell redox homeostasis

Inferred from electronic annotation. Source: Ensembl

positive regulation of DNA repair

Inferred from electronic annotation. Source: Ensembl

regulation of RNA biosynthetic process

Inferred from sequence or structural similarity. Source: GOC

regulation of mRNA stability

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentcentrosome

Inferred from electronic annotation. Source: Ensembl

nuclear speck

Inferred from electronic annotation. Source: Ensembl

nucleolus

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from sequence or structural similarity. Source: UniProtKB

perinuclear region of cytoplasm

Inferred from sequence or structural similarity. Source: UniProtKB

   Molecular_functionDNA binding

Inferred from sequence or structural similarity. Source: UniProtKB

DNA-(apurinic or apyrimidinic site) lyase activity

Inferred from electronic annotation. Source: Ensembl

chromatin DNA binding

Inferred from electronic annotation. Source: Ensembl

damaged DNA binding

Inferred from electronic annotation. Source: Ensembl

metal ion binding

Inferred from sequence or structural similarity. Source: UniProtKB

oxidoreductase activity

Inferred from sequence or structural similarity. Source: UniProtKB

phosphoric diester hydrolase activity

Inferred from electronic annotation. Source: Ensembl

site-specific endodeoxyribonuclease activity, specific for altered base

Inferred from electronic annotation. Source: Ensembl

transcription coactivator activity

Inferred from sequence or structural similarity. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAG49922.1

Sequences

Sequence LengthMass (Da)Tools
Q99PF3 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 67E82454D062CE51

FASTA28932,353
        10         20         30         40         50         60 
KRAAAEDGEE PKSEPETKKS KGAAKKTEKE AAGEGPVLYE DPPDQKTSAS GKSATLKICS 

        70         80         90        100        110        120 
WNVDGLRAWI KKKGLDWVKE EAPDILCLQE TKCSENKLPA ELQELPGLTH QYWSAPSDKE 

       130        140        150        160        170        180 
GYSGVGLLSR QCPLKVSYGI AYVPNAGRGL VRLEYRQRWD EAFRKFLKDL ASRKPLVLCG 

       190        200        210        220        230        240 
DLNVAHEEID LRNPKGNKKN AGFTPQERQG FGEMLQAVPL ADSFRHLYPN TAYAYTFWTY 

       250        260        270        280 
MMNARSKNVG WRLDYFLLSH SLLPALCDSK IRSKALGSDH CPITLYLAL 

« Hide

References

[1]Xie Z.H., Liu C.Z., He Y.H., Wang A.M., Ma C.
Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Norway EMBL AAG49922.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF311054 mRNA. Translation: AAG49922.1.
UniGeneRn.5949.

3D structure databases

ProteinModelPortalQ99PF3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ99PF3. 1 interaction.
MINTMINT-4613115.

Proteomic databases

PRIDEQ99PF3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

RGD2126. Apex1.

Phylogenomic databases

HOVERGENHBG050531.
InParanoidQ99PF3.

Gene expression databases

GenevestigatorQ99PF3.

Family and domain databases

Gene3D3.60.10.10. 2 hits.
InterProIPR004808. AP_endonuc_1.
IPR020847. AP_endonuclease_F1_BS.
IPR020848. AP_endonuclease_F1_CS.
IPR005135. Endo/exonuclease/phosphatase.
[Graphical view]
PANTHERPTHR22748. PTHR22748. 1 hit.
PfamPF03372. Exo_endo_phos. 1 hit.
[Graphical view]
SUPFAMSSF56219. SSF56219. 1 hit.
TIGRFAMsTIGR00633. xth. 2 hits.
PROSITEPS00726. AP_NUCLEASE_F1_1. 1 hit.
PS00727. AP_NUCLEASE_F1_2. 1 hit.
PS00728. AP_NUCLEASE_F1_3. 1 hit.
PS51435. AP_NUCLEASE_F1_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ99PF3_RAT
AccessionPrimary (citable) accession number: Q99PF3
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)