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Protein

Small integral membrane protein 3

Gene

Smim3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Small integral membrane protein 3
Alternative name(s):
NGF-induced differentiation clone 67 protein
Small membrane protein NID67
Gene namesi
Name:Smim3
Synonyms:Nid67
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1917088. Smim3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 40HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000968171 – 60Small integral membrane protein 3Add BLAST60

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei19 – 20CleavageBy similarity2

Proteomic databases

PaxDbiQ99PE5.
PRIDEiQ99PE5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000038059.
CleanExiMM_2010002N04RIK.
ExpressionAtlasiQ99PE5. baseline and differential.
GenevisibleiQ99PE5. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039285.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J2JQ. Eukaryota.
ENOG411180I. LUCA.
GeneTreeiENSGT00390000009443.
HOGENOMiHOG000113786.
HOVERGENiHBG052620.
InParanoidiQ99PE5.
OMAiIYRVRTH.
PhylomeDBiQ99PE5.
TreeFamiTF354124.

Sequencei

Sequence statusi: Complete.

Q99PE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAITQSPVD AVLPKHILDI WAIVLIILAT IVIMTSLFLC PATAVIIYRM
60
RTHPVLNGAA
Length:60
Mass (Da):6,526
Last modified:June 1, 2001 - v1
Checksum:iFCCFE113882A8EA0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti30T → A in AAH12898 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF313412 mRNA. Translation: AAG53958.1.
BC012898 mRNA. Translation: AAH12898.1.
CCDSiCCDS37831.1.
RefSeqiNP_598894.1. NM_134133.2.
XP_006525544.1. XM_006525481.3.
XP_006525545.1. XM_006525482.3.
XP_011245099.1. XM_011246797.1.
UniGeneiMm.273197.

Genome annotation databases

EnsembliENSMUST00000042710; ENSMUSP00000039285; ENSMUSG00000038059.
GeneIDi106878.
KEGGimmu:106878.
UCSCiuc008fag.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF313412 mRNA. Translation: AAG53958.1.
BC012898 mRNA. Translation: AAH12898.1.
CCDSiCCDS37831.1.
RefSeqiNP_598894.1. NM_134133.2.
XP_006525544.1. XM_006525481.3.
XP_006525545.1. XM_006525482.3.
XP_011245099.1. XM_011246797.1.
UniGeneiMm.273197.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039285.

Proteomic databases

PaxDbiQ99PE5.
PRIDEiQ99PE5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042710; ENSMUSP00000039285; ENSMUSG00000038059.
GeneIDi106878.
KEGGimmu:106878.
UCSCiuc008fag.1. mouse.

Organism-specific databases

CTDi85027.
MGIiMGI:1917088. Smim3.

Phylogenomic databases

eggNOGiENOG410J2JQ. Eukaryota.
ENOG411180I. LUCA.
GeneTreeiENSGT00390000009443.
HOGENOMiHOG000113786.
HOVERGENiHBG052620.
InParanoidiQ99PE5.
OMAiIYRVRTH.
PhylomeDBiQ99PE5.
TreeFamiTF354124.

Miscellaneous databases

PROiQ99PE5.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038059.
CleanExiMM_2010002N04RIK.
ExpressionAtlasiQ99PE5. baseline and differential.
GenevisibleiQ99PE5. MM.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiSMIM3_MOUSE
AccessioniPrimary (citable) accession number: Q99PE5
Secondary accession number(s): Q921E9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: June 1, 2001
Last modified: October 5, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.