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Q99P27 (PG12B_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Group XIIB secretory phospholipase A2-like protein
Alternative name(s):
Group XIII secretory phospholipase A2-like protein
Short name=GXIII sPLA2-like
sPLA2-GXIIB
Short name=GXIIB
Gene names
Name:Pla2g12b
Synonyms:Pla2g13
ORF Names:Fksg71
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length195 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Not known; does not seem to have catalytic activity.

Cofactor

Binds 1 calcium ion per subunit By similarity.

Subcellular location

Secreted.

Sequence similarities

Belongs to the phospholipase A2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 195176Group XIIB secretory phospholipase A2-like protein
PRO_0000022773

Sites

Metal binding891Calcium; via carbonyl oxygen By similarity
Metal binding911Calcium; via carbonyl oxygen By similarity
Metal binding931Calcium; via carbonyl oxygen By similarity
Metal binding1161Calcium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q99P27 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 86F8E653BD08DA24

FASTA19521,736
        10         20         30         40         50         60 
MKLLCGFFLL WLGLVGNLAQ SDPSPKEEES YSDWGLRQLR GSFESVNSYV DSFMELLGGK 

        70         80         90        100        110        120 
NGVCQYRCRY GKAPMPRPGY KAQEPNGCSS YFLGIKVPGS MDLGIPAMTK CCNQLDVCYD 

       130        140        150        160        170        180 
TCGANKYRCD AKFRWCLHSI CSDLKRTLGF VSNVEAACDS LADTVFNTVW TLGCRPFMNS 

       190 
QRAACICAEE EKEEL 

« Hide

References

[1]"Cloning and characterization of FKSG71, a novel gene encoding group XIII secreted phospholipase A2."
Wang Y.-G., Gong L.
Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: C57BL/6 X DBA.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF339738 mRNA. Translation: AAK01739.1.
UniGeneMm.30268.

3D structure databases

ProteinModelPortalQ99P27.
SMRQ99P27. Positions 84-174.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ99P27. 1 interaction.

PTM databases

PhosphoSiteQ99P27.

Proteomic databases

PaxDbQ99P27.
PRIDEQ99P27.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:1917086. Pla2g12b.

Phylogenomic databases

eggNOGNOG85984.
HOGENOMHOG000247019.
HOVERGENHBG053577.
InParanoidQ99P27.
PhylomeDBQ99P27.

Gene expression databases

CleanExMM_PLA2G12B.
GenevestigatorQ99P27.

Family and domain databases

Gene3D1.20.90.10. 1 hit.
InterProIPR016090. PLipase_A2_dom.
IPR010711. PLipase_A2_secretory_G12.
[Graphical view]
PANTHERPTHR12824. PTHR12824. 1 hit.
PfamPF06951. PLA2G12. 1 hit.
[Graphical view]
SUPFAMSSF48619. SSF48619. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ99P27.
SOURCESearch...

Entry information

Entry namePG12B_MOUSE
AccessionPrimary (citable) accession number: Q99P27
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot