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Protein
Submitted name:

Beta-2 adrenergic receptor

Gene

Adrb2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-2 adrenergic receptorImported
Gene namesi
Name:Adrb2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 45HelicalSequence analysisAdd BLAST27
Transmembranei57 – 78HelicalSequence analysisAdd BLAST22
Transmembranei99 – 118HelicalSequence analysisAdd BLAST20
Transmembranei147 – 168HelicalSequence analysisAdd BLAST22
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ99P03.

Structurei

3D structure databases

ProteinModelPortaliQ99P03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 275G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST275

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106962.

Family and domain databases

CDDicd15957. 7tmA_Beta2_AR. 1 hit.
InterProiView protein in InterPro
IPR000332. ADRB2_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR24248:SF21. PTHR24248:SF21. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00562. ADRENRGCB2AR.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q99P03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VLVITAIAKF ERLQTVTNYF IISLACADLV MGLAVVPFGA SHILMKMWNF
60 70 80 90 100
GNFWCEFWTS IDVLCVTASI ETLCVIAVDR YVAITSPFKY QSLLTKNKAR
110 120 130 140 150
VVILMVWIVS GLTSFLPIQM HWYRATHKKA IDCYTEETCC DFFTNQAYAI
160 170 180 190 200
ASSIVSFYVP LVVMVFVYSR VFQVAKRQLQ KIDKSEGRFH AQNLSQVEQD
210 220 230 240 250
GRSGHGLRRS SKFCLKEHKA LKTLGIIMGT FTLCWLPFFI VNIVHVIRDN
260 270
LIPKEVYILL NWLGYVNSAF NPLIY
Length:275
Mass (Da):31,468
Last modified:June 1, 2001 - v1
Checksum:i3A14AE4784D7C670
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei275Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY011270 Genomic DNA. Translation: AAG35430.1.
UniGeneiMm.5598.

Similar proteinsi

Entry informationi

Entry nameiQ99P03_MOUSE
AccessioniPrimary (citable) accession number: Q99P03
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)