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Q99NX2

- Q99NX2_RAT

UniProt

Q99NX2 - Q99NX2_RAT

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Protein
Submitted name: ATP7A
Gene
Atp7a
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 5 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. copper-exporting ATPase activity Source: Ensembl
  2. superoxide dismutase copper chaperone activity Source: Ensembl

GO - Biological processi

  1. T-helper cell differentiation Source: Ensembl
  2. blood vessel development Source: Ensembl
  3. blood vessel remodeling Source: Ensembl
  4. cartilage development Source: Ensembl
  5. cellular copper ion homeostasis Source: Ensembl
  6. cerebellar Purkinje cell differentiation Source: Ensembl
  7. collagen fibril organization Source: Ensembl
  8. copper ion import Source: Ensembl
  9. dendrite morphogenesis Source: Ensembl
  10. detoxification of copper ion Source: Ensembl
  11. dopamine metabolic process Source: Ensembl
  12. elastic fiber assembly Source: Ensembl
  13. elastin biosynthetic process Source: Ensembl
  14. epinephrine metabolic process Source: Ensembl
  15. hair follicle morphogenesis Source: Ensembl
  16. locomotory behavior Source: Ensembl
  17. lung alveolus development Source: Ensembl
  18. negative regulation of metalloenzyme activity Source: Ensembl
  19. negative regulation of neuron apoptotic process Source: Ensembl
  20. norepinephrine biosynthetic process Source: Ensembl
  21. peptidyl-lysine modification Source: Ensembl
  22. pigmentation Source: Ensembl
  23. positive regulation of metalloenzyme activity Source: Ensembl
  24. positive regulation of oxidoreductase activity Source: Ensembl
  25. pyramidal neuron development Source: Ensembl
  26. regulation of gene expression Source: Ensembl
  27. regulation of oxidative phosphorylation Source: Ensembl
  28. release of cytochrome c from mitochondria Source: Ensembl
  29. removal of superoxide radicals Source: Ensembl
  30. serotonin metabolic process Source: Ensembl
  31. tryptophan metabolic process Source: Ensembl
  32. tyrosine metabolic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ATP7AImported
Gene namesi
Name:Atp7aImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2179. Atp7a.

Subcellular locationi

GO - Cellular componenti

  1. basolateral plasma membrane Source: Ensembl
  2. late endosome Source: Ensembl
  3. neuron projection Source: Ensembl
  4. neuronal cell body Source: Ensembl
  5. perinuclear region of cytoplasm Source: Ensembl
  6. trans-Golgi network Source: Ensembl
  7. trans-Golgi network transport vesicle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ99NX2.

Structurei

3D structure databases

ProteinModelPortaliQ99NX2.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000250397.
InParanoidiQ99NX2.

Family and domain databases

InterProiIPR017969. Heavy-metal-associated_CS.
IPR006121. HeavyMe-assoc_HMA.
IPR006122. HMA_Cu_ion-bd.
[Graphical view]
PfamiPF00403. HMA. 2 hits.
[Graphical view]
SUPFAMiSSF55008. SSF55008. 2 hits.
TIGRFAMsiTIGR00003. TIGR00003. 2 hits.
PROSITEiPS01047. HMA_1. 2 hits.
PS50846. HMA_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q99NX2-1 [UniParc]FASTAAdd to Basket

« Hide

IVYQPHLITA EEIKKQIEAV GFPAFIKKQP KYLKLGAIDV ERLKSTPVKS    50
SEGSQQKSPA YPSDSAITFT IDGMHCKSCV SNIESALSTL QYVSSIVVSL 100
ENRSAIVKYN ASLVTPEILR KAIEAVSPGQ YRVSISSEVE SPTSSPSSSS 150
LQKMPLNLVS QPLTQEVVIN INGMTCNSCV QSIEGVISKK PGVKSIHVSL 200
TNSTGTIEYD PLLTSPEPLR EAIED 225
Length:225
Mass (Da):24,309
Last modified:June 1, 2001 - v1
Checksum:i5E61F56D67802F0A
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei225 – 2251Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY011398 Genomic DNA. Translation: AAG47432.1.
UniGeneiRn.10554.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY011398 Genomic DNA. Translation: AAG47432.1 .
UniGenei Rn.10554.

3D structure databases

ProteinModelPortali Q99NX2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 2179. Atp7a.

Phylogenomic databases

HOGENOMi HOG000250397.
InParanoidi Q99NX2.

Gene expression databases

Genevestigatori Q99NX2.

Family and domain databases

InterProi IPR017969. Heavy-metal-associated_CS.
IPR006121. HeavyMe-assoc_HMA.
IPR006122. HMA_Cu_ion-bd.
[Graphical view ]
Pfami PF00403. HMA. 2 hits.
[Graphical view ]
SUPFAMi SSF55008. SSF55008. 2 hits.
TIGRFAMsi TIGR00003. TIGR00003. 2 hits.
PROSITEi PS01047. HMA_1. 2 hits.
PS50846. HMA_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular phylogenetics and the origins of placental mammals."
    Murphy W.J., Eizirik E., Johnson W.E., Zhang Y.P., Ryder O.A., O'Brien S.J.
    Nature 409:614-618(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ99NX2_RAT
AccessioniPrimary (citable) accession number: Q99NX2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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