Q99NX2 (Q99NX2_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP7A EMBL AAG47432.1

Gene names

Name:

Atp7a EMBL AAG47432.1 RGD 2179

Organism

Rattus norvegicus (Rat) EMBL AAG47432.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	225 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	T-helper cell differentiation Inferred from electronic annotation. Source: Compara blood vessel development Inferred from electronic annotation. Source: Compara blood vessel remodeling Inferred from electronic annotation. Source: Compara cartilage development Inferred from electronic annotation. Source: Compara cellular copper ion homeostasis Inferred from electronic annotation. Source: Compara cerebellar Purkinje cell differentiation Inferred from electronic annotation. Source: Compara collagen fibril organization Inferred from electronic annotation. Source: Compara copper ion import Inferred from electronic annotation. Source: Compara dendrite morphogenesis Inferred from electronic annotation. Source: Compara detoxification of copper ion Inferred from electronic annotation. Source: Compara dopamine metabolic process Inferred from electronic annotation. Source: Compara elastic fiber assembly Inferred from electronic annotation. Source: Compara elastin biosynthetic process Inferred from electronic annotation. Source: Compara epinephrine metabolic process Inferred from electronic annotation. Source: Compara hair follicle morphogenesis Inferred from electronic annotation. Source: Compara locomotory behavior Inferred from electronic annotation. Source: Compara lung alveolus development Inferred from electronic annotation. Source: Compara negative regulation of metalloenzyme activity Inferred from electronic annotation. Source: Compara negative regulation of neuron apoptotic process Inferred from electronic annotation. Source: Compara norepinephrine biosynthetic process Inferred from electronic annotation. Source: Compara peptidyl-lysine modification Inferred from electronic annotation. Source: Compara pigmentation Inferred from electronic annotation. Source: Compara positive regulation of metalloenzyme activity Inferred from electronic annotation. Source: Compara positive regulation of oxidoreductase activity Inferred from electronic annotation. Source: Compara pyramidal neuron development Inferred from electronic annotation. Source: Compara regulation of gene expression Inferred from electronic annotation. Source: Compara regulation of oxidative phosphorylation Inferred from electronic annotation. Source: Compara release of cytochrome c from mitochondria Inferred from electronic annotation. Source: Compara removal of superoxide radicals Inferred from electronic annotation. Source: Compara serotonin metabolic process Inferred from electronic annotation. Source: Compara skin development Inferred from electronic annotation. Source: Compara tryptophan metabolic process Inferred from electronic annotation. Source: Compara tyrosine metabolic process Inferred from electronic annotation. Source: Compara
Cellular_component	basolateral plasma membrane Inferred from electronic annotation. Source: Compara late endosome Inferred from electronic annotation. Source: Compara neuron projection Inferred from electronic annotation. Source: Compara neuronal cell body Inferred from electronic annotation. Source: Compara perinuclear region of cytoplasm Inferred from electronic annotation. Source: Compara trans-Golgi network Inferred from electronic annotation. Source: Compara trans-Golgi network transport vesicle Inferred from electronic annotation. Source: Compara
Molecular_function	copper-exporting ATPase activity Inferred from electronic annotation. Source: Compara superoxide dismutase copper chaperone activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAG47432.1
	Non-terminal residue	225	1	EMBL AAG47432.1

Sequences

	Sequence		Length	Mass (Da)
	Q99NX2 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 5E61F56D67802F0A	FASTA	225	24,309
	10 20 30 40 50 60 IVYQPHLITA EEIKKQIEAV GFPAFIKKQP KYLKLGAIDV ERLKSTPVKS SEGSQQKSPA 70 80 90 100 110 120 YPSDSAITFT IDGMHCKSCV SNIESALSTL QYVSSIVVSL ENRSAIVKYN ASLVTPEILR 130 140 150 160 170 180 KAIEAVSPGQ YRVSISSEVE SPTSSPSSSS LQKMPLNLVS QPLTQEVVIN INGMTCNSCV 190 200 210 220 QSIEGVISKK PGVKSIHVSL TNSTGTIEYD PLLTSPEPLR EAIED

References

[1]	"Molecular phylogenetics and the origins of placental mammals." Murphy W.J., Eizirik E., Johnson W.E., Zhang Y.P., Ryder O.A., O'Brien S.J. Nature 409:614-618(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY011398 Genomic DNA. Translation: AAG47432.1.
IPI	IPI00952146.
UniGene	Rn.10554.
3D structure databases
HSSP	HSSP built from PDB template 1AW0 based on UniProtKB Q04656.
ProteinModelPortal	Q99NX2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q99NX2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
RGD	2179. Atp7a.
Phylogenomic databases
HOGENOM	HOG000250397.
InParanoid	Q99NX2.
Gene expression databases
ArrayExpress	Q99NX2.
Genevestigator	Q99NX2.
Family and domain databases
InterPro	IPR017969. Heavy-metal-associated_CS. IPR006121. HeavyMe-assoc_HMA. IPR006122. HMA_Cu_ion-bd. [Graphical view]
Pfam	PF00403. HMA. 2 hits. [Graphical view]
SUPFAM	SSF55008. HeavyMe_transpt. 2 hits.
TIGRFAMs	TIGR00003. TIGR00003. 2 hits.
PROSITE	PS01047. HMA_1. 2 hits. PS50846. HMA_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q99NX2_RAT

Accession

Primary (citable) accession number: Q99NX2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	April 3, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)