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Q99NU3 (Q99NU3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Cnr1 EMBL AAG37743.1
OrganismMus musculus (Mouse) EMBL AAG37743.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length331 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU000688
   Molecular functionG-protein coupled receptor RuleBase RU000688
Receptor
Transducer
Gene Ontology (GO)
   Biological_processadenylate cyclase-modulating G-protein coupled receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

aging

Inferred from electronic annotation. Source: Ensembl

maternal process involved in female pregnancy

Inferred from electronic annotation. Source: Ensembl

memory

Inferred from electronic annotation. Source: Ensembl

negative regulation of action potential

Inferred from electronic annotation. Source: Ensembl

negative regulation of blood pressure

Inferred from electronic annotation. Source: Ensembl

negative regulation of dopamine secretion

Inferred from electronic annotation. Source: Ensembl

negative regulation of fatty acid beta-oxidation

Inferred from electronic annotation. Source: Ensembl

negative regulation of mast cell activation

Inferred from electronic annotation. Source: Ensembl

negative regulation of nitric-oxide synthase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of acute inflammatory response to antigenic stimulus

Inferred from electronic annotation. Source: Ensembl

positive regulation of apoptotic process

Inferred from electronic annotation. Source: Ensembl

positive regulation of blood pressure

Inferred from electronic annotation. Source: Ensembl

positive regulation of fever generation

Inferred from electronic annotation. Source: Ensembl

positive regulation of neuron projection development

Inferred from electronic annotation. Source: Ensembl

regulation of feeding behavior

Inferred from electronic annotation. Source: Ensembl

regulation of insulin secretion

Inferred from electronic annotation. Source: Ensembl

regulation of penile erection

Inferred from electronic annotation. Source: Ensembl

regulation of synaptic transmission, GABAergic

Inferred from electronic annotation. Source: Ensembl

regulation of synaptic transmission, glutamatergic

Inferred from electronic annotation. Source: Ensembl

response to cocaine

Inferred from electronic annotation. Source: Ensembl

response to ethanol

Inferred from electronic annotation. Source: Ensembl

response to lipopolysaccharide

Inferred from electronic annotation. Source: Ensembl

response to morphine

Inferred from electronic annotation. Source: Ensembl

response to nicotine

Inferred from electronic annotation. Source: Ensembl

response to nutrient

Inferred from electronic annotation. Source: Ensembl

sensory perception of pain

Inferred from electronic annotation. Source: Ensembl

spermatogenesis

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncannabinoid receptor activity

Inferred from electronic annotation. Source: Ensembl

drug binding

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAG37743.1
Non-terminal residue3311 EMBL AAG37743.1

Sequences

Sequence LengthMass (Da)Tools
Q99NU3 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 795EC0BA3F594881

FASTA33137,316
        10         20         30         40         50         60 
FRGSPFQEKM TAGDNSPLVP AGDTTNITEF YNKSLSSFKE NEDNIQCGEN FMDMECFMIL 

        70         80         90        100        110        120 
NPSQQLAIAV LSLTLGTFTV LENLLVLCVI LHSRSLRCRP SYHFIGSLAV ADLLGSVIFV 

       130        140        150        160        170        180 
YSFVDFHVFH RKDSPNVFLF KLGGVTASFT ASVGSLFLTA IDRYISIHRP LAYKRIVTRP 

       190        200        210        220        230        240 
KAVVAFCLMW TIAIVIAVLP LLGWNCKKLQ SVCSDIFPLI DETYLMFWIG VTSVLLLFIV 

       250        260        270        280        290        300 
YAYMYILWKA HSHAVRMIQR GTQKSIIIHT SEDGKVQVTR PDQARMDIRL AKTLVLILVV 

       310        320        330 
LIICWGPLLA IMVYDVFGKM NKLIKTVFAF C 

« Hide

References

[1]"Molecular phylogenetics and the origins of placental mammals."
Murphy W.J., Eizirik E., Johnson W.E., Zhang Y.P., Ryder O.A., O'Brien S.J.
Nature 409:614-618(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY011579 Genomic DNA. Translation: AAG37743.1.
UniGeneMm.7992.

3D structure databases

ProteinModelPortalQ99NU3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000081787.

Chemistry

BindingDBQ99NU3.

Protein family/group databases

GPCRDBSearch...

Proteomic databases

PRIDEQ99NU3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG051045.
InParanoidQ99NU3.

Gene expression databases

ArrayExpressQ99NU3.
BgeeQ99NU3.
GenevestigatorQ99NU3.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR000810. Canbinoid_rcpt_1.
IPR002230. Cnbnoid_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERPTHR22750:SF10. PTHR22750:SF10. 1 hit.
PfamPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSPR00522. CANABINOID1R.
PR00362. CANNABINOIDR.
PR00237. GPCRRHODOPSN.
PROSITEPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ99NU3_MOUSE
AccessionPrimary (citable) accession number: Q99NU3
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)