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Q99NU3

- Q99NU3_MOUSE

UniProt

Q99NU3 - Q99NU3_MOUSE

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Protein
Submitted name: Cannabinoid receptor 1
Gene
Cnr1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. cannabinoid receptor activity Source: Ensembl
  2. drug binding Source: Ensembl
Complete GO annotation...

GO - Biological processi

  1. adenylate cyclase-modulating G-protein coupled receptor signaling pathway Source: Ensembl
  2. aging Source: Ensembl
  3. maternal process involved in female pregnancy Source: Ensembl
  4. memory Source: Ensembl
  5. negative regulation of action potential Source: Ensembl
  6. negative regulation of blood pressure Source: Ensembl
  7. negative regulation of dopamine secretion Source: Ensembl
  8. negative regulation of fatty acid beta-oxidation Source: Ensembl
  9. negative regulation of mast cell activation Source: Ensembl
  10. negative regulation of nitric-oxide synthase activity Source: Ensembl
  11. positive regulation of acute inflammatory response to antigenic stimulus Source: Ensembl
  12. positive regulation of apoptotic process Source: Ensembl
  13. positive regulation of blood pressure Source: Ensembl
  14. positive regulation of fever generation Source: Ensembl
  15. positive regulation of neuron projection development Source: Ensembl
  16. regulation of feeding behavior Source: Ensembl
  17. regulation of insulin secretion Source: Ensembl
  18. regulation of penile erection Source: Ensembl
  19. regulation of synaptic transmission, GABAergic Source: Ensembl
  20. regulation of synaptic transmission, glutamatergic Source: Ensembl
  21. response to cocaine Source: Ensembl
  22. response to ethanol Source: Ensembl
  23. response to lipopolysaccharide Source: Ensembl
  24. response to morphine Source: Ensembl
  25. response to nicotine Source: Ensembl
  26. response to nutrient Source: Ensembl
  27. sensory perception of pain Source: Ensembl
  28. spermatogenesis Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Cannabinoid receptor 1Imported
Gene namesi
Name:Cnr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ99NU3.

Expressioni

Gene expression databases

ArrayExpressiQ99NU3.
BgeeiQ99NU3.
GenevestigatoriQ99NU3.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000081787.

Structurei

3D structure databases

ProteinModelPortaliQ99NU3.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOVERGENiHBG051045.
InParanoidiQ99NU3.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000810. Canbinoid_rcpt_1.
IPR002230. Cnbnoid_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR22750:SF10. PTHR22750:SF10. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00522. CANABINOID1R.
PR00362. CANNABINOIDR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q99NU3-1 [UniParc]FASTAAdd to Basket

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FRGSPFQEKM TAGDNSPLVP AGDTTNITEF YNKSLSSFKE NEDNIQCGEN    50
FMDMECFMIL NPSQQLAIAV LSLTLGTFTV LENLLVLCVI LHSRSLRCRP 100
SYHFIGSLAV ADLLGSVIFV YSFVDFHVFH RKDSPNVFLF KLGGVTASFT 150
ASVGSLFLTA IDRYISIHRP LAYKRIVTRP KAVVAFCLMW TIAIVIAVLP 200
LLGWNCKKLQ SVCSDIFPLI DETYLMFWIG VTSVLLLFIV YAYMYILWKA 250
HSHAVRMIQR GTQKSIIIHT SEDGKVQVTR PDQARMDIRL AKTLVLILVV 300
LIICWGPLLA IMVYDVFGKM NKLIKTVFAF C 331
Length:331
Mass (Da):37,316
Last modified:June 1, 2001 - v1
Checksum:i795EC0BA3F594881
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei331 – 3311Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY011579 Genomic DNA. Translation: AAG37743.1.
UniGeneiMm.7992.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY011579 Genomic DNA. Translation: AAG37743.1 .
UniGenei Mm.7992.