##gff-version 3
Q99NH8	UniProtKB	Signal peptide	1	18	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q99NH8	UniProtKB	Chain	19	227	.	.	.	ID=PRO_0000014988;Note=Triggering receptor expressed on myeloid cells 2	
Q99NH8	UniProtKB	Topological domain	19	171	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q99NH8	UniProtKB	Transmembrane	172	192	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q99NH8	UniProtKB	Topological domain	193	227	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q99NH8	UniProtKB	Domain	29	112	.	.	.	Note=Ig-like V-type	
Q99NH8	UniProtKB	Binding site	67	67	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9NZC2	
Q99NH8	UniProtKB	Binding site	88	88	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9NZC2	
Q99NH8	UniProtKB	Site	157	158	.	.	.	Note=Cleavage of ectodomain;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28855301;Dbxref=PMID:28855301	
Q99NH8	UniProtKB	Glycosylation	20	20	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q99NH8	UniProtKB	Glycosylation	79	79	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9NZC2	
Q99NH8	UniProtKB	Disulfide bond	36	110	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9NZC2	
Q99NH8	UniProtKB	Disulfide bond	51	60	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9NZC2	
Q99NH8	UniProtKB	Alternative sequence	162	227	.	.	.	ID=VSP_010794;Note=In isoform 2. NQETSFPPTSILLLLACVLLSKFLAASILWAVARGRQKPGTPVVRGLDCGQDAGHQLQILTGPGGT->QVSSCGSPLAYHLPPLSKESRDLLPTHLHSSPPGLRSPEQVSCSQHPLGCGQGQAEAGNTCGQRAGLWPRCWAPTSDPHWTRRYVREF;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12472885;Dbxref=PMID:12472885	
Q99NH8	UniProtKB	Natural variant	78	78	.	.	.	Note=In strain: FVB/N. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=PMID:15489334	
Q99NH8	UniProtKB	Mutagenesis	47	47	.	.	.	Note=Decreases myeloid cell immune response. Reduces expression levels. R->H;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:29794134,ECO:0000269|PubMed:29859094;Dbxref=PMID:29794134,PMID:29859094	
Q99NH8	UniProtKB	Mutagenesis	66	66	.	.	.	Note=Macrophages exhibit increased apoptosis%2C reduced proliferation%2C and reduced phagocytosis. Macrophages also exhibit increased inflammatory cytokine secretion. Microglia demonstrate reduced immune activity. Also decreases cerebral blood flow and reduces cerebral glucose metabolism. T->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28559417;Dbxref=PMID:28559417	
Q99NH8	UniProtKB	Sequence conflict	105	105	.	.	.	Note=A->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q99NH8	UniProtKB	Sequence conflict	118	118	.	.	.	Note=A->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q99NH8	UniProtKB	Sequence conflict	122	122	.	.	.	Note=Q->K;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q99NH8	UniProtKB	Sequence conflict	148	148	.	.	.	Note=S->E;Ontology_term=ECO:0000305;evidence=ECO:0000305