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Protein
Submitted name:

GATA-3

Gene

Gata3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-5689880. Ub-specific processing proteases.
R-RNO-8939236. RUNX1 regulates transcription of genes involved in differentiation of HSCs.
R-RNO-983231. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Submitted name:
GATA-3Imported
Submitted name:
GATA-binding protein 3Imported
Gene namesi
Name:Gata3Imported
ORF Names:rCG_55727Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 17

Organism-specific databases

RGDi621250. Gata3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000019336.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026187.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini258 – 312GATA-typeInterPro annotationAdd BLAST55
Domaini312 – 365GATA-typeInterPro annotationAdd BLAST54

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1601. Eukaryota.
COG5641. LUCA.
GeneTreeiENSGT00760000119221.
HOGENOMiHOG000047701.
HOVERGENiHBG051705.
KOiK17895.
OMAiQRYPPTH.
OrthoDBiEOG091G0AUR.
TreeFamiTF315391.

Family and domain databases

Gene3Di3.30.50.10. 2 hits.
InterProiView protein in InterPro
IPR029521. GATA-3.
IPR016374. TF_GATA-2/3.
IPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
PANTHERiPTHR10071:SF106. PTHR10071:SF106. 1 hit.
PfamiView protein in Pfam
PF00320. GATA. 2 hits.
PIRSFiPIRSF003027. TF_GATA-1/2/3. 1 hit.
PRINTSiPR00619. GATAZNFINGER.
SMARTiView protein in SMART
SM00401. ZnF_GATA. 2 hits.
PROSITEiView protein in PROSITE
PS00344. GATA_ZN_FINGER_1. 2 hits.
PS50114. GATA_ZN_FINGER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q99NH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVTTDQPRW VSHHHPAVLN GQHPDTHHPG LGHSYMDPAQ YPLTEEVDVL
60 70 80 90 100
FNIDGQGNHV PSYYGNSVRA TVQRYPPTHH GSQVCRPPLL HGSLPWLDGG
110 120 130 140 150
KALSSHHTAS PWNLSPFSKT SIHHGSPGPL SVYPPASSSS LAAGHSSPHL
160 170 180 190 200
FTFPPTPPKD VSPDPSLSTP GSAGSARQDE KECLKYQVQL PDSMKLETSH
210 220 230 240 250
SRGSMTTLGG ASSSAHHPIT TYPPYVPEYS SGLFPPSSLL GGSPTGFGCK
260 270 280 290 300
SRPKARSSTE GRECVNCGAT STPLWRRDGT GHYLCNACGL YHKMNGQNRP
310 320 330 340 350
LIKPKRRLSA ARRAGTSCAN CQTTTTTLWR RNANGDPVCN ACGLYYKLHN
360 370 380 390 400
INRPLTMKKE GIQTRNRKMS SKSKKCKKVH DALEDFPKSS SFNPAALSRH
410 420 430 440
MSSLSHISPF SHSSHMLTTP TPMHPPSGLS FGPHHPSSMV TAMG
Length:444
Mass (Da):48,081
Last modified:June 1, 2001 - v1
Checksum:i427384F766659388
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07028502 Genomic DNA. No translation available.
AY024364 mRNA. Translation: AAK00586.1.
CH473990 Genomic DNA. Translation: EDL78630.1.
RefSeqiNP_579827.1. NM_133293.1.
XP_006254315.1. XM_006254253.3.
XP_008770115.1. XM_008771893.1.
XP_008770116.1. XM_008771894.2.
XP_017456155.1. XM_017600666.1.
UniGeneiRn.229174.

Genome annotation databases

EnsembliENSRNOT00000026187; ENSRNOP00000026187; ENSRNOG00000019336.
GeneIDi85471.
KEGGirno:85471.
UCSCiRGD:621250. rat.

Similar proteinsi

Entry informationi

Entry nameiQ99NH5_RAT
AccessioniPrimary (citable) accession number: Q99NH5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 22, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported