Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

RWD domain-containing protein 1

Gene

Rwdd1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Protects DRG2 from proteolytic degradation.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
RWD domain-containing protein 1
Alternative name(s):
Small androgen receptor-interacting protein
Gene namesi
Name:Rwdd1
Synonyms:Sarip
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi631337 Rwdd1

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000975422 – 243RWD domain-containing protein 1Add BLAST242

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylthreonineBy similarity1
Modified residuei144PhosphothreonineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ99ND9
PRIDEiQ99ND9

Expressioni

Gene expression databases

BgeeiENSRNOG00000042916

Interactioni

Subunit structurei

Interacts with DRG2 (By similarity). Interacts with androgen receptor.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000062656

Structurei

3D structure databases

ProteinModelPortaliQ99ND9
SMRiQ99ND9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 114RWDPROSITE-ProRule annotationAdd BLAST105

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni142 – 197Interaction with DRG2By similarityAdd BLAST56

Sequence similaritiesi

Belongs to the RWDD1/GIR2 family.Curated

Phylogenomic databases

eggNOGiKOG4018 Eukaryota
ENOG410XT0M LUCA
GeneTreeiENSGT00390000009168
HOVERGENiHBG060864
InParanoidiQ99ND9
OMAiIYCGELE
OrthoDBiEOG091G0ODA
PhylomeDBiQ99ND9

Family and domain databases

Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR006575 RWD-domain
IPR016135 UBQ-conjugating_enzyme/RWD
IPR032378 ZC3H15/TMA46_C
PfamiView protein in Pfam
PF16543 DFRP_C, 1 hit
PF05773 RWD, 1 hit
SMARTiView protein in SMART
SM00591 RWD, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS50908 RWD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q99ND9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDYGEEQRN ELEALESIYP DSFTVLSENP PSFTITVTSE AGENDETVQT
60 70 80 90 100
TLKFTYSEKY PDEAPLYEIF SQENLEDNDV SDILKLLALQ AEENLGMVMI
110 120 130 140 150
FTLVTAVQEK LNEIVDQIKT RREEEKKQKE KEAEEAEKKL FHGTPVTIEN
160 170 180 190 200
FLSWKAKFDA ELLEIKKKRM KEEEQAGKNK LSGKQLFETD HNLDTSDIQF
210 220 230 240
LEDAGNNVEV DESLFQEMDD LELEDGEDDP DYNPVAPGSD SSD
Length:243
Mass (Da):27,782
Last modified:June 1, 2001 - v1
Checksum:i57EA63249E2B3813
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ132390 mRNA Translation: CAC24710.1
RefSeqiNP_671487.1, NM_147146.2
UniGeneiRn.234293
Rn.23942

Genome annotation databases

EnsembliENSRNOT00000068777; ENSRNOP00000062656; ENSRNOG00000042916
GeneIDi259218
KEGGirno:259218
UCSCiRGD:631337 rat

Similar proteinsi

Entry informationi

Entry nameiRWDD1_RAT
AccessioniPrimary (citable) accession number: Q99ND9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health