Unreviewed, UniProtKB/TrEMBL Q99NB4 (Q99NB4_RAT)

Names and origin

Protein names

Submitted name:
    Cyclin D1 EMBL BAB40333.1

Gene names

Name:

Ccnd1 RGD 68384

Organism

Rattus norvegicus (Rat) EMBL BAB40333.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	191 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the cyclin family. RuleBase RU000383V1

Ontologies

Keywords
Biological process	Cell cycle Cell division RuleBase RU003481V0
Molecular function	Cyclin RuleBase RU000383V1 EMBL BAB40333.1
Gene Ontology (GO)
Biological process	Leydig cell differentiation Inferred from mutant phenotype. Source: RGD Wnt receptor signaling pathway through beta-catenin Inferred from electronic annotation. Source: Compara cell division Inferred from electronic annotation. Source: UniProtKB-KW endoplasmic reticulum unfolded protein response Inferred from electronic annotation. Source: Compara fat cell differentiation Inferred from electronic annotation. Source: Compara liver development Inferred from expression pattern. Source: RGD negative regulation of Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of epithelial cell differentiation Inferred from electronic annotation. Source: Compara organ regeneration Inferred from expression pattern. Source: RGD positive regulation of cell proliferation Inferred from mutant phenotype. Source: RGD protein amino acid phosphorylation Inferred from electronic annotation. Source: Compara re-entry into mitotic cell cycle Inferred from electronic annotation. Source: Compara regulation of cell cycle Traceable author statement. Source: RGD response to X-ray Inferred from expression pattern. Source: RGD response to calcium ion Inferred from expression pattern. Source: RGD response to corticosterone stimulus Inferred from expression pattern. Source: RGD response to drug Inferred from expression pattern. Source: RGD response to estrogen stimulus Inferred from expression pattern. Source: RGD response to ethanol Inferred from expression pattern. Source: RGD response to iron ion Inferred from expression pattern. Source: RGD response to magnesium ion Inferred from expression pattern. Source: RGD response to organic cyclic substance Inferred from expression pattern. Source: RGD response to organic nitrogen Inferred from direct assay. Source: RGD response to vitamin E Inferred from expression pattern. Source: RGD
Cellular component	cyclin-dependent protein kinase holoenzyme complex Inferred from electronic annotation. Source: Compara cytoplasm Inferred from direct assay. Source: RGD nucleus Inferred from direct assay. Source: RGD
Molecular function	cyclin-dependent protein kinase regulator activity Inferred from electronic annotation. Source: Compara protein complex binding Inferred from physical interaction. Source: RGD protein kinase activity Inferred from electronic annotation. Source: Compara protein kinase binding Inferred from direct assay. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	191	1	EMBL BAB40333.1

Sequences

	Sequence		Length	Mass (Da)
	Q99NB4-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: AA97B6E0F332EDEE	FASTA	191	22,203
	10 20 30 40 50 60 MEHQLLCCEV ETIRRAYPDT NLLNDRVLRA MLKTEETCAP SVSYFKCVQR EIVPSMRKIV 70 80 90 100 110 120 ATWMLEVCEE QKCEEEVFPL AMNYLDRFLS LEPLKKSRLQ LLGATCMFVA SKMKETIPLT 130 140 150 160 170 180 AEKLCIYTDN SIRPEELLQM ELLLVNKLKW NLAAMTPHDF IEHFLSKMPE ADENKQIIRK 190 HAQTFVALCA T

References

[1]	"Characterization of rat cyclin D1 5' flanking region." Moriuchi A., Ido A., Tsubouchi H. Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Wistar EMBL BAB40333.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB042564 Genomic DNA. Translation: BAB40333.1.
IPI	IPI00190352.
UniGene	Rn.22279
3D structure databases
HSSP	HSSP built from PDB template 1VIN based on UniProtKB P30274.
ModBase	Search...
Protein-protein interaction databases
STRING	Q99NB4.
Genome annotation databases
Ensembl	ENSRNOT00000028411; ENSRNOP00000028411; ENSRNOG00000020918; Rattus norvegicus. [Genome view] ENSRNOT00000064546; ENSRNOP00000063177; ENSRNOG00000020918; Rattus norvegicus. [Genome view]
Phylogenomic databases
HOVERGEN	Q99NB4.
Gene expression databases
ArrayExpress	Q99NB4.
Genevestigator	Q99NB4.
Family and domain databases
InterPro	IPR015451. CycD. IPR006670. Cyclin. IPR011028. Cyclin-like. IPR004367. Cyclin_C. IPR006671. Cyclin_N. IPR013763. Cyclin_related. [Graphical view]
Gene3D	G3DSA:1.10.472.10. Cyclin_related. 1 hit.
PANTHER	PTHR10177:SF12. CycD. 1 hit.
Pfam	PF02984. Cyclin_C. 1 hit. PF00134. Cyclin_N. 1 hit. [Graphical view]
SMART	SM00385. CYCLIN. 1 hit. [Graphical view]
PROSITE	PS00292. CYCLINS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q99NB4_RAT

Accession

Primary (citable) accession number: Q99NB4

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	November 3, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)