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Q99NB4 (Q99NB4_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Ccnd1 RGD 68384
OrganismRattus norvegicus (Rat) EMBL BAB40333.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length191 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the cyclin family. RuleBase RU000383

Ontologies

Keywords
   Molecular functionCyclin RuleBase RU000383 EMBL BAB40333.1
Gene Ontology (GO)
   Biological_processcanonical Wnt signaling pathway

Inferred from electronic annotation. Source: Ensembl

endoplasmic reticulum unfolded protein response

Inferred from electronic annotation. Source: Ensembl

fat cell differentiation

Inferred from electronic annotation. Source: Ensembl

lactation

Inferred from electronic annotation. Source: Ensembl

mammary gland alveolus development

Inferred from electronic annotation. Source: Ensembl

mammary gland epithelial cell proliferation

Inferred from electronic annotation. Source: Ensembl

mitotic G1 DNA damage checkpoint

Inferred from electronic annotation. Source: Ensembl

negative regulation of Wnt signaling pathway

Inferred from electronic annotation. Source: Ensembl

negative regulation of epithelial cell differentiation

Inferred from electronic annotation. Source: Ensembl

positive regulation of cyclin-dependent protein kinase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of mammary gland epithelial cell proliferation

Inferred from electronic annotation. Source: Ensembl

re-entry into mitotic cell cycle

Inferred from electronic annotation. Source: Ensembl

response to UV-A

Inferred from electronic annotation. Source: Ensembl

response to drug

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentcyclin-dependent protein kinase holoenzyme complex

Inferred from electronic annotation. Source: Ensembl

cytoplasm

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from electronic annotation. Source: Ensembl

tight junction

Inferred from electronic annotation. Source: Ensembl

   Molecular_functioncyclin-dependent protein serine/threonine kinase regulator activity

Inferred from electronic annotation. Source: Ensembl

protein kinase activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue1911 EMBL BAB40333.1

Sequences

Sequence LengthMass (Da)Tools
Q99NB4 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: AA97B6E0F332EDEE

FASTA19122,203
        10         20         30         40         50         60 
MEHQLLCCEV ETIRRAYPDT NLLNDRVLRA MLKTEETCAP SVSYFKCVQR EIVPSMRKIV 

        70         80         90        100        110        120 
ATWMLEVCEE QKCEEEVFPL AMNYLDRFLS LEPLKKSRLQ LLGATCMFVA SKMKETIPLT 

       130        140        150        160        170        180 
AEKLCIYTDN SIRPEELLQM ELLLVNKLKW NLAAMTPHDF IEHFLSKMPE ADENKQIIRK 

       190 
HAQTFVALCA T 

« Hide

References

[1]"Characterization of rat cyclin D1 5' flanking region."
Moriuchi A., Ido A., Tsubouchi H.
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Wistar EMBL BAB40333.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB042564 Genomic DNA. Translation: BAB40333.1.
UniGeneRn.22279.

3D structure databases

ProteinModelPortalQ99NB4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

RGD68384. Ccnd1.

Phylogenomic databases

HOVERGENHBG107315.
InParanoidQ99NB4.

Gene expression databases

GenevestigatorQ99NB4.

Family and domain databases

Gene3D1.10.472.10. 1 hit.
InterProIPR013763. Cyclin-like.
IPR015451. Cyclin_D.
IPR006671. Cyclin_N.
[Graphical view]
PANTHERPTHR10177:SF67. PTHR10177:SF67. 1 hit.
PfamPF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMSSF47954. SSF47954. 1 hit.
PROSITEPS00292. CYCLINS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ99NB4_RAT
AccessionPrimary (citable) accession number: Q99NB4
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)