Idh3B

Functionⁱ

GO - Molecular functionⁱ

magnesium ion binding Source: InterPro
NAD binding Source: InterPro
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: NAD+-specific isocitrate dehydrogenase b-subunitImported
Gene namesⁱ	Name:Idh3BImported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus

Organism-specific databases

Rat genome database More...RGDⁱ	621881. Idh3B.

RGDⁱ

621881. Idh3B.

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q99NA6.
PRIDEⁱ	Q99NA6.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000007316.

Bgeeⁱ

ENSRNOG00000007316.

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	Q99NA6. 1 interactor.
STRINGⁱ	10116.ENSRNOP00000009681.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q99NA6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 136	Iso_dhInterPro annotationAdd BLAST		136

Phylogenomic databases

eggNOGⁱ	KOG0784. Eukaryota. COG0473. LUCA.
HOVERGENⁱ	HBG052080.

Family and domain databases

InterProⁱ	View protein in InterPro IPR019818. IsoCit/isopropylmalate_DH_CS. IPR024084. IsoPropMal-DH-like_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00180. Iso_dh. 1 hit.
SMARTⁱ	View protein in SMART SM01329. Iso_dh. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00470. IDH_IMDH. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q99NA6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
PKIKFETMII DNCCMQLVQN PYQFDVLVMP NLYGNIIDNL AAGLVGGAGV 
        60         70         80         90        100
VPGESYSAEY AVFETGARHP FAQAVGRNIA NPTAMLLSAS NMLRHLNLEY 
       110        120        130        140 
HSSMIADAVK KVIKVGKVRT RDMGGYSTTT DFIKSVIGHL HPHGG

Length:145

Mass (Da):15,706

Last modified:June 1, 2001 - v1

Checksum:ⁱ7E14F1AF6A0FD452

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB047540 mRNA. Translation: BAB32674.1.
UniGeneⁱ	Rn.1093.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB047540 mRNA. Translation: BAB32674.1.
UniGeneⁱ	Rn.1093.

3D structure databases

ProteinModelPortalⁱ	Q99NA6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	Q99NA6. 1 interactor.
STRINGⁱ	10116.ENSRNOP00000009681.

Proteomic databases

PaxDbⁱ	Q99NA6.
PRIDEⁱ	Q99NA6.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Organism-specific databases

Rat genome database More...RGDⁱ	621881. Idh3B.

RGDⁱ

621881. Idh3B.

Phylogenomic databases

eggNOGⁱ	KOG0784. Eukaryota. COG0473. LUCA.
HOVERGENⁱ	HBG052080.

Gene expression databases

Bgeeⁱ	ENSRNOG00000007316.

Bgeeⁱ

ENSRNOG00000007316.

Family and domain databases

InterProⁱ	View protein in InterPro IPR019818. IsoCit/isopropylmalate_DH_CS. IPR024084. IsoPropMal-DH-like_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00180. Iso_dh. 1 hit.
SMARTⁱ	View protein in SMART SM01329. Iso_dh. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00470. IDH_IMDH. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q99NA6_RAT
Accessionⁱ	Q99NA6Primary (citable) accession number: Q99NA6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 1, 2001
	Last sequence update:	June 1, 2001
	Last modified:	May 10, 2017
	This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - Q99NA6 (Q99NA6_RAT)

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NAD+-specific isocitrate dehydrogenase b-subunit

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q99NA6 (Q99NA6_RAT)

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NAD+-specific isocitrate dehydrogenase b-subunit

Idh3B

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ