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Protein
Submitted name:

NAD+-specific isocitrate dehydrogenase b-subunit

Gene

Idh3B

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. NAD binding Source: InterPro
  3. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NAD+-specific isocitrate dehydrogenase b-subunitImported
Gene namesi
Name:Idh3BImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621881. Idh3B.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: Ensembl
  2. nucleus Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ99NA6. baseline and differential.
GenevestigatoriQ99NA6.

Interactioni

Protein-protein interaction databases

IntActiQ99NA6. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ99NA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG052080.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q99NA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PKIKFETMII DNCCMQLVQN PYQFDVLVMP NLYGNIIDNL AAGLVGGAGV
60 70 80 90 100
VPGESYSAEY AVFETGARHP FAQAVGRNIA NPTAMLLSAS NMLRHLNLEY
110 120 130 140
HSSMIADAVK KVIKVGKVRT RDMGGYSTTT DFIKSVIGHL HPHGG
Length:145
Mass (Da):15,706
Last modified:May 31, 2001 - v1
Checksum:i7E14F1AF6A0FD452
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB047540 mRNA. Translation: BAB32674.1.
UniGeneiRn.1093.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB047540 mRNA. Translation: BAB32674.1.
UniGeneiRn.1093.

3D structure databases

ProteinModelPortaliQ99NA6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ99NA6. 1 interaction.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi621881. Idh3B.

Phylogenomic databases

HOVERGENiHBG052080.

Gene expression databases

ExpressionAtlasiQ99NA6. baseline and differential.
GenevestigatoriQ99NA6.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Expression of NAD+-dependent isocitrate dehydrogenase in brown adipose tissue."
    Shinohara Y., Daikoku T., Kajimoto K., Shima A., Yamazaki N., Terada H.
    Biochem. Biophys. Res. Commun. 281:634-638(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ99NA6_RAT
AccessioniPrimary (citable) accession number: Q99NA6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2001
Last sequence update: May 31, 2001
Last modified: October 28, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.