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Protein

39S ribosomal protein L16, mitochondrial

Gene

Mrpl16

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the large subunit of mitochondrial ribosome.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L16, mitochondrial
Short name:
L16mt
Short name:
MRP-L16
Gene namesi
Name:Mrpl16
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:2137219. Mrpl16.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: MGI
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3636MitochondrionSequence analysisAdd
BLAST
Chaini37 – 25121539S ribosomal protein L16, mitochondrialPRO_0000239842Add
BLAST

Proteomic databases

EPDiQ99N93.
MaxQBiQ99N93.
PaxDbiQ99N93.
PeptideAtlasiQ99N93.
PRIDEiQ99N93.

PTM databases

iPTMnetiQ99N93.
PhosphoSiteiQ99N93.

Expressioni

Gene expression databases

BgeeiQ99N93.
CleanExiMM_MRPL16.
GenevisibleiQ99N93. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000128915.

Structurei

3D structure databases

ProteinModelPortaliQ99N93.
SMRiQ99N93. Positions 47-251.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L16P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3422. Eukaryota.
COG0197. LUCA.
GeneTreeiENSGT00390000002038.
HOGENOMiHOG000021349.
HOVERGENiHBG056553.
InParanoidiQ99N93.
KOiK02878.
OMAiPYDLTHK.
OrthoDBiEOG7HQN8X.
PhylomeDBiQ99N93.
TreeFamiTF312969.

Family and domain databases

Gene3Di3.90.1170.10. 1 hit.
InterProiIPR016180. Ribosomal_L10e/L16.
IPR000114. Ribosomal_L16.
[Graphical view]
PANTHERiPTHR12220. PTHR12220. 1 hit.
PfamiPF00252. Ribosomal_L16. 1 hit.
[Graphical view]
PRINTSiPR00060. RIBOSOMALL16.
SUPFAMiSSF54686. SSF54686. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q99N93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRLLTRVPA PLLRMHFSDS WAALPTSAGL KTLLPVPTFE NVSIPERSKL
60 70 80 90 100
KFVERVPLVP KVRREPKNLK DIRGPSTEAT DFTEGNFAIL ALGGGYLHWG
110 120 130 140 150
HFEMMRLTIN RFMDPKNMFA IWRVPAPFKP ITRKGVGQRM GGGKGAIDHY
160 170 180 190 200
VTPVKTGCLV VEMGGRCEFE EVKGILNQVA HKLPFPAKAV SRKTLERMHQ
210 220 230 240 250
NQRERELNNQ NPWTFEHIAT ANMFGIRKFL SPYDLTQKGR YWGKFYMPKR

V
Length:251
Mass (Da):28,804
Last modified:June 1, 2001 - v1
Checksum:i8753B4DBBCC63ABB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049643 mRNA. Translation: BAB40848.1.
AK165616 mRNA. Translation: BAE38296.1.
BC044721 mRNA. Translation: AAH44721.1.
CCDSiCCDS29610.1.
RefSeqiNP_079882.2. NM_025606.3.
UniGeneiMm.203928.

Genome annotation databases

EnsembliENSMUST00000167199; ENSMUSP00000128915; ENSMUSG00000024683.
GeneIDi94063.
KEGGimmu:94063.
UCSCiuc008gsx.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049643 mRNA. Translation: BAB40848.1.
AK165616 mRNA. Translation: BAE38296.1.
BC044721 mRNA. Translation: AAH44721.1.
CCDSiCCDS29610.1.
RefSeqiNP_079882.2. NM_025606.3.
UniGeneiMm.203928.

3D structure databases

ProteinModelPortaliQ99N93.
SMRiQ99N93. Positions 47-251.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000128915.

PTM databases

iPTMnetiQ99N93.
PhosphoSiteiQ99N93.

Proteomic databases

EPDiQ99N93.
MaxQBiQ99N93.
PaxDbiQ99N93.
PeptideAtlasiQ99N93.
PRIDEiQ99N93.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000167199; ENSMUSP00000128915; ENSMUSG00000024683.
GeneIDi94063.
KEGGimmu:94063.
UCSCiuc008gsx.1. mouse.

Organism-specific databases

CTDi54948.
MGIiMGI:2137219. Mrpl16.

Phylogenomic databases

eggNOGiKOG3422. Eukaryota.
COG0197. LUCA.
GeneTreeiENSGT00390000002038.
HOGENOMiHOG000021349.
HOVERGENiHBG056553.
InParanoidiQ99N93.
KOiK02878.
OMAiPYDLTHK.
OrthoDBiEOG7HQN8X.
PhylomeDBiQ99N93.
TreeFamiTF312969.

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Miscellaneous databases

PROiQ99N93.
SOURCEiSearch...

Gene expression databases

BgeeiQ99N93.
CleanExiMM_MRPL16.
GenevisibleiQ99N93. MM.

Family and domain databases

Gene3Di3.90.1170.10. 1 hit.
InterProiIPR016180. Ribosomal_L10e/L16.
IPR000114. Ribosomal_L16.
[Graphical view]
PANTHERiPTHR12220. PTHR12220. 1 hit.
PfamiPF00252. Ribosomal_L16. 1 hit.
[Graphical view]
PRINTSiPR00060. RIBOSOMALL16.
SUPFAMiSSF54686. SSF54686. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
    Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
    J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Colon.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Heart, Kidney, Liver and Spleen.

Entry informationi

Entry nameiRM16_MOUSE
AccessioniPrimary (citable) accession number: Q99N93
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: June 1, 2001
Last modified: July 6, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.