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Protein

28S ribosomal protein S18a, mitochondrial

Gene

Mrps18a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: UniProtKB

GO - Biological processi

  • mitochondrial translation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S18a, mitochondrial
Short name:
MRP-S18-a
Short name:
Mrps18a
Short name:
S18mt-a
Alternative name(s):
28S ribosomal protein S18-3, mitochondrial
Short name:
MRP-S18-3
Gene namesi
Name:Mrps18a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1915815. Mrps18a.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: GO_Central
  • mitochondrial small ribosomal subunit Source: UniProtKB
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 34MitochondrionSequence analysisAdd BLAST34
ChainiPRO_000003062635 – 19628S ribosomal protein S18a, mitochondrialAdd BLAST162

Proteomic databases

EPDiQ99N85.
MaxQBiQ99N85.
PaxDbiQ99N85.
PRIDEiQ99N85.

PTM databases

iPTMnetiQ99N85.
PhosphoSitePlusiQ99N85.
SwissPalmiQ99N85.

Expressioni

Gene expression databases

CleanExiMM_MRPS18A.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024763.

Structurei

3D structure databases

ProteinModelPortaliQ99N85.
SMRiQ99N85.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S18P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3162. Eukaryota.
COG0238. LUCA.
HOGENOMiHOG000139370.
HOVERGENiHBG058800.
InParanoidiQ99N85.
KOiK02963.
PhylomeDBiQ99N85.

Family and domain databases

Gene3Di4.10.640.10. 1 hit.
InterProiIPR001648. Ribosomal_S18.
[Graphical view]
PfamiPF01084. Ribosomal_S18. 1 hit.
[Graphical view]
ProDomiPD002239. Ribosomal_S18. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF46911. SSF46911. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q99N85-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALRRLVSG CGRQLQAFLA GPAATGWLWL PARGLREVVK IQEGKTTVIE
60 70 80 90 100
GRITETPKAT PDPPNPSGQC PICRWNLKHK YTYEDVLLLS QFIRPYGGML
110 120 130 140 150
PRRVTGLCRE EHRKIEECVK MAHRAGLLPN HRPQLPEGCL PKDKPKLNRY
160 170 180 190
LTRWAPKSVK PIYKKGHRWN KVGMAVGSPL LKDNVCYSRR PLKMMH
Length:196
Mass (Da):22,321
Last modified:June 1, 2001 - v1
Checksum:i1E0CB8F311F19E0F
GO

Sequence cautioni

The sequence AAH25456 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti6R → A in BAB22794 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049953 mRNA. Translation: BAB41006.1.
AK003444 mRNA. Translation: BAB22794.1.
BC025456 mRNA. Translation: AAH25456.1. Different initiation.
CCDSiCCDS28819.1.
RefSeqiNP_081044.1. NM_026768.3.
UniGeneiMm.287443.

Genome annotation databases

GeneIDi68565.
KEGGimmu:68565.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049953 mRNA. Translation: BAB41006.1.
AK003444 mRNA. Translation: BAB22794.1.
BC025456 mRNA. Translation: AAH25456.1. Different initiation.
CCDSiCCDS28819.1.
RefSeqiNP_081044.1. NM_026768.3.
UniGeneiMm.287443.

3D structure databases

ProteinModelPortaliQ99N85.
SMRiQ99N85.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024763.

PTM databases

iPTMnetiQ99N85.
PhosphoSitePlusiQ99N85.
SwissPalmiQ99N85.

Proteomic databases

EPDiQ99N85.
MaxQBiQ99N85.
PaxDbiQ99N85.
PRIDEiQ99N85.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi68565.
KEGGimmu:68565.

Organism-specific databases

CTDi55168.
MGIiMGI:1915815. Mrps18a.

Phylogenomic databases

eggNOGiKOG3162. Eukaryota.
COG0238. LUCA.
HOGENOMiHOG000139370.
HOVERGENiHBG058800.
InParanoidiQ99N85.
KOiK02963.
PhylomeDBiQ99N85.

Miscellaneous databases

ChiTaRSiMrps18a. mouse.
PROiQ99N85.
SOURCEiSearch...

Gene expression databases

CleanExiMM_MRPS18A.

Family and domain databases

Gene3Di4.10.640.10. 1 hit.
InterProiIPR001648. Ribosomal_S18.
[Graphical view]
PfamiPF01084. Ribosomal_S18. 1 hit.
[Graphical view]
ProDomiPD002239. Ribosomal_S18. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF46911. SSF46911. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRT18A_MOUSE
AccessioniPrimary (citable) accession number: Q99N85
Secondary accession number(s): Q8R3H2, Q9D1J6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.