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Protein

Ferritin heavy polypeptide-like 17

Gene

Fthl17

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27IronPROSITE-ProRule annotation1
Metal bindingi107IronPROSITE-ProRule annotation1
Metal bindingi141IronPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIron storage
LigandIron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ferritin heavy polypeptide-like 17
Gene namesi
Name:Fthl17
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1933180. Fthl17.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002010691 – 176Ferritin heavy polypeptide-like 17Add BLAST176

Proteomic databases

PaxDbiQ99MX2.
PRIDEiQ99MX2.

Expressioni

Tissue specificityi

Testis specific.

Gene expression databases

BgeeiENSMUSG00000071815.
CleanExiMM_FTHL17.
GenevisibleiQ99MX2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000094254.

Structurei

3D structure databases

ProteinModelPortaliQ99MX2.
SMRiQ99MX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 159Ferritin-like diironPROSITE-ProRule annotationAdd BLAST150

Sequence similaritiesi

Belongs to the ferritin family.Curated

Phylogenomic databases

eggNOGiKOG2332. Eukaryota.
COG1528. LUCA.
GeneTreeiENSGT00760000119129.
HOGENOMiHOG000223383.
HOVERGENiHBG000410.
InParanoidiQ99MX2.
OrthoDBiEOG091G0KPY.
PhylomeDBiQ99MX2.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
InterProiView protein in InterPro
IPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
PANTHERiPTHR11431. PTHR11431. 1 hit.
PfamiView protein in Pfam
PF00210. Ferritin. 1 hit.
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiView protein in PROSITE
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q99MX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEAPSRMQQ NYDWQCEDAI NTHIQLCLYA SYEYMSMAVY FDRDDVAQEN
60 70 80 90 100
FKRFFLTKSH NCQTSAEMFM HLQNKRGGCS SLQGIARPER DSWHGGFQAM
110 120 130 140 150
ECAFHMEMLI NQSLLNMHEV AKEKGDPHLC HFLEQNCLDQ QVDILKEMSG
160 170
YLTNLRQMGA VEHNLAEYLF DKLSLS
Length:176
Mass (Da):20,491
Last modified:September 18, 2013 - v2
Checksum:i590A4D44F063324C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti80S → I in AAK31948 (PubMed:11279525).Curated1
Sequence conflicti84G → D in AAK31948 (PubMed:11279525).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF285569 mRNA. Translation: AAK31948.1.
AL806531 Genomic DNA. No translation available.
CCDSiCCDS30003.1.
RefSeqiNP_112551.2. NM_031261.2.
UniGeneiMm.388703.

Genome annotation databases

EnsembliENSMUST00000096509; ENSMUSP00000094254; ENSMUSG00000071815.
GeneIDi83457.
KEGGimmu:83457.
UCSCiuc009spm.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiFHL17_MOUSE
AccessioniPrimary (citable) accession number: Q99MX2
Secondary accession number(s): L7MU38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: September 18, 2013
Last modified: August 30, 2017
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families