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Protein
Submitted name:

WSL-1-like protein

Gene

Tnfrsf25

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
WSL-1-like proteinImported
Gene namesi
Name:Tnfrsf25Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1934667. Tnfrsf25.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei199 – 220HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_500432283233 – 413Sequence analysisAdd BLAST381

Structurei

3D structure databases

ProteinModelPortaliQ99MM1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 122TNFR-CysInterPro annotationAdd BLAST44
Domaini328 – 409DeathInterPro annotationAdd BLAST82

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000049228.
HOVERGENiHBG058493.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022329. TNFR_25.
[Graphical view]
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01972. TNFACTORR25.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 2 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99MM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEARLLRGCV VEPLFLPLLL LLLLLLLLGG QGQGGMSGRC DCASESQKRY
60 70 80 90 100
GPFCCRGCPK GHYMKAPCAE PCGNSTCLPC PSDTFLTRDN HFKTDCTRCQ
110 120 130 140 150
VCDEEALQVT LENCSAKSDT HCGCQSGWCV DCSTVPCGKS SPFSCVPCGA
160 170 180 190 200
TTPVHEAPTP RPCLPGFYIR GNDCTSCPTG FSSVCPKACT AVCGWKQMFW
210 220 230 240 250
VQVLLGVAFL FGAILICAYC RWQPCKAVVT ADTAGTEPLA SPQTAHLSAS
260 270 280 290 300
DSAHTLLAPP SSTGKICTTV QLVGNNWTPG LSQTQEVVCG QASQPWDQLP
310 320 330 340 350
NRTLGTPLAS PLSPAPPAGS PAAVLQPGPQ LYDVMDAVPA RRWKEFVRTL
360 370 380 390 400
GLREAEIEAV EVEICRFRDQ QYEMLKRWRQ QQPAGLGAIY AALERKGLEG
410
CAEDLRSRLQ RGP
Length:413
Mass (Da):44,453
Last modified:June 1, 2001 - v1
Checksum:i69F21B85D0DABABF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329969 mRNA. Translation: AAK11256.1.
UniGeneiMm.101198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329969 mRNA. Translation: AAK11256.1.
UniGeneiMm.101198.

3D structure databases

ProteinModelPortaliQ99MM1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1934667. Tnfrsf25.

Phylogenomic databases

HOGENOMiHOG000049228.
HOVERGENiHBG058493.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022329. TNFR_25.
[Graphical view]
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01972. TNFACTORR25.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 2 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ99MM1_MOUSE
AccessioniPrimary (citable) accession number: Q99MM1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 5, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.