Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q99MI5 (Q99MI5_RAT)

UniProt

Q99MI5 - Q99MI5_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Protein LOC100912604

Gene

LOC100912604

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • spermidine synthase activity Source: RGD

GO - Biological processi

  • spermidine biosynthetic process Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-351202. Metabolism of polyamines.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein LOC100912604Imported
Submitted name:
Spermidine synthaseImported
Gene namesi
Name:LOC100912604Imported
Synonyms:LOC100364487Imported, SrmImported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus
Proteomesi
  • UP000002494 Componentsi: Chromosome 3, Chromosome 5

Organism-specific databases

RGDi6485978. LOC100912604.
620796. Srm.

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL2429.

Expressioni

Gene expression databases

BgeeiENSRNOG00000011078.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000067465.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini18 – 253236PABS (polyamine biosynthesis)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the spermidine/spermine synthase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410ITKE. Eukaryota.
COG0421. LUCA.
GeneTreeiENSGT00620000088039.
HOGENOMiHOG000256147.
HOVERGENiHBG000834.
KOiK00797.
OMAiLEAYCTT.
OrthoDBiEOG091G07LZ.
TreeFamiTF314466.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00198. Spermidine_synth. 1 hit.
InterProiIPR030374. PABS.
IPR030373. PABS_CS.
IPR029063. SAM-dependent_MTases.
IPR001045. Spermi_synthase.
IPR030668. Spermi_synthase_euk.
[Graphical view]
PIRSFiPIRSF000502. Spermidine_synth. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00417. speE. 1 hit.
PROSITEiPS01330. PABS_1. 1 hit.
PS51006. PABS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99MI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPGPDGPAA PGPAAIREGW FRETCSLWPG QALSLQVEQL LHHRRSRYQD 
        60         70         80         90        100
ILVFRSKTYG NVLVLDGVIQ CTERDEFSYQ EMIANLPLCS HPNPRKVLII 
       110        120        130        140        150
GGGDGGVLRE VVKHPSVESV VQCEIDEDVI EVSKKFLPGM AVGYSSSKLT 
       160        170        180        190        200
LHVGDGFEFM KQNQDAFDVI ITDSSDPMGP AESLFKESYY QLMKTALKED 
       210        220        230        240        250
GILCCQGECQ WLHLDLIKEM RHFCKSLFPV VSYAYCTIPT YPSGQIGFML 
       260        270        280        290        300
CSKNPSTNFR EPVQQLTQAQ VEQMQLKYYN SDMHRAAFVL PEFTRKALND 

IS
Length:302
Mass (Da):33,997
Last modified:June 1, 2001 - v1
Checksum:iEDB401A122B43C99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050449 Genomic DNA. No translation available.
AABR07051514 Genomic DNA. No translation available.
BC128733 mRNA. Translation: AAI28734.1.
AF337636 mRNA. Translation: AAK21288.1.
RefSeqiNP_445916.1. NM_053464.2.
XP_003749506.1. XM_003749458.2.
UniGeneiRn.22258.

Genome annotation databases

EnsembliENSRNOT00000014934; ENSRNOP00000014934; ENSRNOG00000011078.
ENSRNOT00000071712; ENSRNOP00000067465; ENSRNOG00000046379.
GeneIDi100912604.
84596.
KEGGirno:100912604.
rno:84596.
UCSCiRGD:620796. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050449 Genomic DNA. No translation available.
AABR07051514 Genomic DNA. No translation available.
BC128733 mRNA. Translation: AAI28734.1.
AF337636 mRNA. Translation: AAK21288.1.
RefSeqiNP_445916.1. NM_053464.2.
XP_003749506.1. XM_003749458.2.
UniGeneiRn.22258.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000067465.

Chemistry

ChEMBLiCHEMBL2429.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000014934; ENSRNOP00000014934; ENSRNOG00000011078.
ENSRNOT00000071712; ENSRNOP00000067465; ENSRNOG00000046379.
GeneIDi100912604.
84596.
KEGGirno:100912604.
rno:84596.
UCSCiRGD:620796. rat.

Organism-specific databases

CTDi6723.
RGDi6485978. LOC100912604.
620796. Srm.

Phylogenomic databases

eggNOGiENOG410ITKE. Eukaryota.
COG0421. LUCA.
GeneTreeiENSGT00620000088039.
HOGENOMiHOG000256147.
HOVERGENiHBG000834.
KOiK00797.
OMAiLEAYCTT.
OrthoDBiEOG091G07LZ.
TreeFamiTF314466.

Enzyme and pathway databases

ReactomeiR-RNO-351202. Metabolism of polyamines.

Gene expression databases

BgeeiENSRNOG00000011078.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00198. Spermidine_synth. 1 hit.
InterProiIPR030374. PABS.
IPR030373. PABS_CS.
IPR029063. SAM-dependent_MTases.
IPR001045. Spermi_synthase.
IPR030668. Spermi_synthase_euk.
[Graphical view]
PIRSFiPIRSF000502. Spermidine_synth. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00417. speE. 1 hit.
PROSITEiPS01330. PABS_1. 1 hit.
PS51006. PABS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ99MI5_RAT
AccessioniPrimary (citable) accession number: Q99MI5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.