Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Kallikrein related-peptidase 10

Gene

Klk10

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. serine-type endopeptidase activity Source: InterPro
Complete GO annotation...

Protein family/group databases

MEROPSiS01.489.

Names & Taxonomyi

Protein namesi
Submitted name:
Kallikrein related-peptidase 10Imported
Submitted name:
Protein Klk10Imported
Gene namesi
Name:Klk10Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1916790. Klk10.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiQ99M20.
PaxDbiQ99M20.
PRIDEiQ99M20.

Expressioni

Gene expression databases

BgeeiQ99M20.
GenevestigatoriQ99M20.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000014058.

Structurei

3D structure databases

ProteinModelPortaliQ99M20.
SMRiQ99M20. Positions 50-275.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5640.
GeneTreeiENSGT00760000118862.
HOGENOMiHOG000251820.
HOVERGENiHBG013304.
InParanoidiQ99M20.
KOiK09619.
OMAiYNRSLSC.
OrthoDBiEOG75B84T.
PhylomeDBiQ99M20.
TreeFamiTF331065.

Family and domain databases

InterProiIPR001254. Peptidase_S1.
IPR018114. Peptidase_S1_AS.
IPR001314. Peptidase_S1A.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99M20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVPLLHLST ASGSWSLVKL LLPLLMVQLW AAQALLLPGN ATRVDLEASG
60 70 80 90 100
AQCERDYHPW QVSLFHNLQF QCAGVLVDQN WVLTAAHCWR NKPLRARVGD
110 120 130 140 150
DHLLLFQKEQ LRSTSSPVFH PKYQACSGPI LPHRSDEHDL MMLKLSSPVM
160 170 180 190 200
LTSNVHPVQL PFRCSQPGQE CQVSGWGTSA SRRVKYNRSL SCSKVTLLSQ
210 220 230 240 250
KQCETFYPGV ITNSMICAEA DGNQDSCQSD SGGPLVCDDT LHGVLSWGIY
260 270
PCGAAQHPSV YSEICKYTPW IRRVIRFK
Length:278
Mass (Da):31,044
Last modified:June 1, 2001 - v1
Checksum:iDD68E44E9AECCF55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151989 Genomic DNA. No translation available.
BC002100 mRNA. Translation: AAH02100.1.
RefSeqiNP_598473.1. NM_133712.2.
UniGeneiMm.46421.

Genome annotation databases

EnsembliENSMUST00000014058; ENSMUSP00000014058; ENSMUSG00000030693.
GeneIDi69540.
KEGGimmu:69540.
UCSCiuc009gnq.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151989 Genomic DNA. No translation available.
BC002100 mRNA. Translation: AAH02100.1.
RefSeqiNP_598473.1. NM_133712.2.
UniGeneiMm.46421.

3D structure databases

ProteinModelPortaliQ99M20.
SMRiQ99M20. Positions 50-275.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000014058.

Protein family/group databases

MEROPSiS01.489.

Proteomic databases

MaxQBiQ99M20.
PaxDbiQ99M20.
PRIDEiQ99M20.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000014058; ENSMUSP00000014058; ENSMUSG00000030693.
GeneIDi69540.
KEGGimmu:69540.
UCSCiuc009gnq.1. mouse.

Organism-specific databases

CTDi5655.
MGIiMGI:1916790. Klk10.

Phylogenomic databases

eggNOGiCOG5640.
GeneTreeiENSGT00760000118862.
HOGENOMiHOG000251820.
HOVERGENiHBG013304.
InParanoidiQ99M20.
KOiK09619.
OMAiYNRSLSC.
OrthoDBiEOG75B84T.
PhylomeDBiQ99M20.
TreeFamiTF331065.

Miscellaneous databases

NextBioi329716.
PROiQ99M20.
SOURCEiSearch...

Gene expression databases

BgeeiQ99M20.
GenevestigatoriQ99M20.

Family and domain databases

InterProiIPR001254. Peptidase_S1.
IPR018114. Peptidase_S1_AS.
IPR001314. Peptidase_S1A.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Mix FVB/NImported.
    Tissue: Mammary tumor. WAP-TGF alpha model. 7 months oldImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ99M20_MOUSE
AccessioniPrimary (citable) accession number: Q99M20
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 1, 2015
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.