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Q99M20

- Q99M20_MOUSE

UniProt

Q99M20 - Q99M20_MOUSE

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Protein
Submitted name: Kallikrein related-peptidase 10
Gene
Klk10
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. serine-type endopeptidase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Protein family/group databases

    MEROPSiS01.489.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Kallikrein related-peptidase 10Imported
    Submitted name:
    Protein Klk10Imported
    Gene namesi
    Name:Klk10Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:1916790. Klk10.

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotations

    Expressioni

    Gene expression databases

    GenevestigatoriQ99M20.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000014058.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG5640.
    GeneTreeiENSGT00750000117409.
    HOGENOMiHOG000251820.
    HOVERGENiHBG013304.
    InParanoidiQ99M20.
    KOiK09619.
    OMAiYNRSLSC.
    OrthoDBiEOG75B84T.
    TreeFamiTF331065.

    Family and domain databases

    InterProiIPR001254. Peptidase_S1.
    IPR018114. Peptidase_S1_AS.
    IPR001314. Peptidase_S1A.
    IPR009003. Trypsin-like_Pept_dom.
    [Graphical view]
    PfamiPF00089. Trypsin. 1 hit.
    [Graphical view]
    PRINTSiPR00722. CHYMOTRYPSIN.
    SMARTiSM00020. Tryp_SPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF50494. SSF50494. 1 hit.
    PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
    PS00134. TRYPSIN_HIS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q99M20-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRVPLLHLST ASGSWSLVKL LLPLLMVQLW AAQALLLPGN ATRVDLEASG    50
    AQCERDYHPW QVSLFHNLQF QCAGVLVDQN WVLTAAHCWR NKPLRARVGD 100
    DHLLLFQKEQ LRSTSSPVFH PKYQACSGPI LPHRSDEHDL MMLKLSSPVM 150
    LTSNVHPVQL PFRCSQPGQE CQVSGWGTSA SRRVKYNRSL SCSKVTLLSQ 200
    KQCETFYPGV ITNSMICAEA DGNQDSCQSD SGGPLVCDDT LHGVLSWGIY 250
    PCGAAQHPSV YSEICKYTPW IRRVIRFK 278
    Length:278
    Mass (Da):31,044
    Last modified:June 1, 2001 - v1
    Checksum:iDD68E44E9AECCF55
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151989 Genomic DNA. No translation available.
    BC002100 mRNA. Translation: AAH02100.1.
    RefSeqiNP_598473.1. NM_133712.2.
    UniGeneiMm.46421.

    Genome annotation databases

    EnsembliENSMUST00000014058; ENSMUSP00000014058; ENSMUSG00000030693.
    GeneIDi69540.
    KEGGimmu:69540.
    UCSCiuc009gnq.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151989 Genomic DNA. No translation available.
    BC002100 mRNA. Translation: AAH02100.1 .
    RefSeqi NP_598473.1. NM_133712.2.
    UniGenei Mm.46421.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000014058.

    Protein family/group databases

    MEROPSi S01.489.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000014058 ; ENSMUSP00000014058 ; ENSMUSG00000030693 .
    GeneIDi 69540.
    KEGGi mmu:69540.
    UCSCi uc009gnq.1. mouse.

    Organism-specific databases

    CTDi 5655.
    MGIi MGI:1916790. Klk10.

    Phylogenomic databases

    eggNOGi COG5640.
    GeneTreei ENSGT00750000117409.
    HOGENOMi HOG000251820.
    HOVERGENi HBG013304.
    InParanoidi Q99M20.
    KOi K09619.
    OMAi YNRSLSC.
    OrthoDBi EOG75B84T.
    TreeFami TF331065.

    Miscellaneous databases

    NextBioi 329716.
    PROi Q99M20.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q99M20.

    Family and domain databases

    InterProi IPR001254. Peptidase_S1.
    IPR018114. Peptidase_S1_AS.
    IPR001314. Peptidase_S1A.
    IPR009003. Trypsin-like_Pept_dom.
    [Graphical view ]
    Pfami PF00089. Trypsin. 1 hit.
    [Graphical view ]
    PRINTSi PR00722. CHYMOTRYPSIN.
    SMARTi SM00020. Tryp_SPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50494. SSF50494. 1 hit.
    PROSITEi PS50240. TRYPSIN_DOM. 1 hit.
    PS00134. TRYPSIN_HIS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Mix FVB/NImported.
      Tissue: Mammary tumor. WAP-TGF alpha model. 7 months oldImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ99M20_MOUSE
    AccessioniPrimary (citable) accession number: Q99M20
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: September 3, 2014
    This is version 99 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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