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Protein

Cytochrome c oxidase assembly factor 5

Gene

Coa5

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in an early step of the mitochondrial complex IV assembly process.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase assembly factor 5
Gene namesi
Name:Coa5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1923428. Coa5.

Subcellular locationi

GO - Cellular componenti

  • mitochondrion Source: MGI

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003258771 – 74Cytochrome c oxidase assembly factor 5Add BLAST74

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 57PROSITE-ProRule annotation
Modified residuei37PhosphoserineBy similarity1
Disulfide bondi41 ↔ 47PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Phosphoprotein

Proteomic databases

MaxQBiQ99M07.
PaxDbiQ99M07.
PeptideAtlasiQ99M07.
PRIDEiQ99M07.

PTM databases

PhosphoSitePlusiQ99M07.

Expressioni

Gene expression databases

BgeeiENSMUSG00000026112.
CleanExiMM_6330578E17RIK.
GenevisibleiQ99M07. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027286.

Structurei

3D structure databases

ProteinModelPortaliQ99M07.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 65CHCHPROSITE-ProRule annotationAdd BLAST39

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi30 – 41Cx10C motifPROSITE-ProRule annotationAdd BLAST12
Motifi47 – 57Cx9C motifPROSITE-ProRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the PET191 family.Curated

Phylogenomic databases

eggNOGiKOG4114. Eukaryota.
ENOG4111YIY. LUCA.
GeneTreeiENSGT00390000005548.
HOVERGENiHBG107093.
InParanoidiQ99M07.
KOiK18178.
OMAiLLESECC.
OrthoDBiEOG09040N9K.
PhylomeDBiQ99M07.
TreeFamiTF313953.

Family and domain databases

InterProiView protein in InterPro
IPR018793. Cyt_c_oxidase_assmbl_Pet191.
PfamiView protein in Pfam
PF10203. Pet191_N. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q99M07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRYYEDKPE GGACAGVKED LGACLLQSAC VLQEGKSPRQ CLKEGNCRAL
60 70
QYSFFECKRS MLDARSRFRG RKGY
Length:74
Mass (Da):8,359
Last modified:June 1, 2001 - v1
Checksum:i3B74D7FA804C771F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK166651 mRNA. Translation: BAE38918.1.
AK169639 mRNA. Translation: BAE41270.1.
BC002137 mRNA. Translation: AAH02137.1.
CCDSiCCDS35541.1.
RefSeqiNP_932123.3. NM_198006.4.
UniGeneiMm.28085.

Genome annotation databases

EnsembliENSMUST00000027286; ENSMUSP00000027286; ENSMUSG00000026112.
GeneIDi76178.
KEGGimmu:76178.
UCSCiuc007aro.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK166651 mRNA. Translation: BAE38918.1.
AK169639 mRNA. Translation: BAE41270.1.
BC002137 mRNA. Translation: AAH02137.1.
CCDSiCCDS35541.1.
RefSeqiNP_932123.3. NM_198006.4.
UniGeneiMm.28085.

3D structure databases

ProteinModelPortaliQ99M07.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027286.

PTM databases

PhosphoSitePlusiQ99M07.

Proteomic databases

MaxQBiQ99M07.
PaxDbiQ99M07.
PeptideAtlasiQ99M07.
PRIDEiQ99M07.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000027286; ENSMUSP00000027286; ENSMUSG00000026112.
GeneIDi76178.
KEGGimmu:76178.
UCSCiuc007aro.2. mouse.

Organism-specific databases

CTDi493753.
MGIiMGI:1923428. Coa5.

Phylogenomic databases

eggNOGiKOG4114. Eukaryota.
ENOG4111YIY. LUCA.
GeneTreeiENSGT00390000005548.
HOVERGENiHBG107093.
InParanoidiQ99M07.
KOiK18178.
OMAiLLESECC.
OrthoDBiEOG09040N9K.
PhylomeDBiQ99M07.
TreeFamiTF313953.

Miscellaneous databases

PROiQ99M07.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026112.
CleanExiMM_6330578E17RIK.
GenevisibleiQ99M07. MM.

Family and domain databases

InterProiView protein in InterPro
IPR018793. Cyt_c_oxidase_assmbl_Pet191.
PfamiView protein in Pfam
PF10203. Pet191_N. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOA5_MOUSE
AccessioniPrimary (citable) accession number: Q99M07
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 1, 2001
Last modified: February 15, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.