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Protein

Transcriptional adapter 1

Gene

Tada1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probably involved in transcriptional regulation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional adapter 1
Alternative name(s):
Transcriptional adapter 1-like protein
Gene namesi
Name:Tada1
Synonyms:Tada1l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1196415. Tada1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003160161 – 335Transcriptional adapter 1Add BLAST335

Proteomic databases

EPDiQ99LM9.
MaxQBiQ99LM9.
PaxDbiQ99LM9.
PeptideAtlasiQ99LM9.
PRIDEiQ99LM9.

PTM databases

PhosphoSitePlusiQ99LM9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000026563.
ExpressionAtlasiQ99LM9. baseline and differential.
GenevisibleiQ99LM9. MM.

Interactioni

Subunit structurei

Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.By similarity

Protein-protein interaction databases

IntActiQ99LM9. 2 interactors.
MINTiMINT-7985016.
STRINGi10090.ENSMUSP00000027846.

Structurei

3D structure databases

ProteinModelPortaliQ99LM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TADA1 family.Curated

Phylogenomic databases

eggNOGiENOG410IJ0B. Eukaryota.
ENOG4111F9I. LUCA.
GeneTreeiENSGT00390000011644.
HOGENOMiHOG000035120.
HOVERGENiHBG099848.
InParanoidiQ99LM9.
KOiK11317.
OMAiEARMMVT.
OrthoDBiEOG091G0ILW.
PhylomeDBiQ99LM9.
TreeFamiTF324330.

Family and domain databases

InterProiIPR024738. Hfi1/Tada1.
[Graphical view]
PfamiPF12767. SAGA-Tad1. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99LM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATFVSELEA AKKNLSEALG DNVKQYWANL KLWFKQKISK EEFDLEAHRL
60 70 80 90 100
LTQDNVHSHN DFLLAILTRC QILVSTPEGA GSLPWTGGSA AKPGKPKGKK
110 120 130 140 150
KLSSVRQKFD HRFQPQNPLS GAQQFVAKEP QGDDDLKLCS HTMMLPTRGQ
160 170 180 190 200
LEGRMIVTAY EHGLDNVTEE AVSAVVYAVE NHLKDILTSV VSRRKAYRVR
210 220 230 240 250
DGHFKYAFGS NVTPQPYLKN SVVAYNNLVE GPPAFSAPCA NQSPASQPHP
260 270 280 290 300
DDAEQQAAFL LACSGDTLPA SLPPVNMYDL FEALQVHREV IPTHTVYALN
310 320 330
IERIIMKLWH PNHEELQQDK VHRQRLAAKE GLLLC
Length:335
Mass (Da):37,409
Last modified:June 1, 2001 - v1
Checksum:iF3CC5374DA55F918
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK151132 mRNA. Translation: BAE30140.1.
BC002307 mRNA. Translation: AAH02307.1.
BC027337 mRNA. Translation: AAH27337.1.
CCDSiCCDS15450.1.
RefSeqiNP_084521.1. NM_030245.3.
UniGeneiMm.100665.
Mm.192094.

Genome annotation databases

EnsembliENSMUST00000027846; ENSMUSP00000027846; ENSMUSG00000026563.
GeneIDi27878.
KEGGimmu:27878.
UCSCiuc007dkm.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK151132 mRNA. Translation: BAE30140.1.
BC002307 mRNA. Translation: AAH02307.1.
BC027337 mRNA. Translation: AAH27337.1.
CCDSiCCDS15450.1.
RefSeqiNP_084521.1. NM_030245.3.
UniGeneiMm.100665.
Mm.192094.

3D structure databases

ProteinModelPortaliQ99LM9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ99LM9. 2 interactors.
MINTiMINT-7985016.
STRINGi10090.ENSMUSP00000027846.

PTM databases

PhosphoSitePlusiQ99LM9.

Proteomic databases

EPDiQ99LM9.
MaxQBiQ99LM9.
PaxDbiQ99LM9.
PeptideAtlasiQ99LM9.
PRIDEiQ99LM9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000027846; ENSMUSP00000027846; ENSMUSG00000026563.
GeneIDi27878.
KEGGimmu:27878.
UCSCiuc007dkm.2. mouse.

Organism-specific databases

CTDi117143.
MGIiMGI:1196415. Tada1.

Phylogenomic databases

eggNOGiENOG410IJ0B. Eukaryota.
ENOG4111F9I. LUCA.
GeneTreeiENSGT00390000011644.
HOGENOMiHOG000035120.
HOVERGENiHBG099848.
InParanoidiQ99LM9.
KOiK11317.
OMAiEARMMVT.
OrthoDBiEOG091G0ILW.
PhylomeDBiQ99LM9.
TreeFamiTF324330.

Miscellaneous databases

ChiTaRSiTada1. mouse.
PROiQ99LM9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026563.
ExpressionAtlasiQ99LM9. baseline and differential.
GenevisibleiQ99LM9. MM.

Family and domain databases

InterProiIPR024738. Hfi1/Tada1.
[Graphical view]
PfamiPF12767. SAGA-Tad1. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTADA1_MOUSE
AccessioniPrimary (citable) accession number: Q99LM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 1, 2001
Last modified: November 30, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.