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Protein

Transcriptional adapter 1

Gene

Tada1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probably involved in transcriptional regulation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional adapter 1
Alternative name(s):
Transcriptional adapter 1-like protein
Gene namesi
Name:Tada1
Synonyms:Tada1l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1196415 Tada1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003160161 – 335Transcriptional adapter 1Add BLAST335

Proteomic databases

EPDiQ99LM9
MaxQBiQ99LM9
PaxDbiQ99LM9
PeptideAtlasiQ99LM9
PRIDEiQ99LM9

PTM databases

iPTMnetiQ99LM9
PhosphoSitePlusiQ99LM9

Expressioni

Gene expression databases

BgeeiENSMUSG00000026563
ExpressionAtlasiQ99LM9 baseline and differential
GenevisibleiQ99LM9 MM

Interactioni

Subunit structurei

Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.By similarity

Protein-protein interaction databases

IntActiQ99LM9, 2 interactors
MINTiQ99LM9
STRINGi10090.ENSMUSP00000027846

Structurei

3D structure databases

ProteinModelPortaliQ99LM9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TADA1 family.Curated

Phylogenomic databases

eggNOGiENOG410IJ0B Eukaryota
ENOG4111F9I LUCA
GeneTreeiENSGT00390000011644
HOGENOMiHOG000035120
HOVERGENiHBG099848
InParanoidiQ99LM9
KOiK11317
OMAiIMKLWHP
OrthoDBiEOG091G0ILW
PhylomeDBiQ99LM9
TreeFamiTF324330

Family and domain databases

InterProiView protein in InterPro
IPR024738 Hfi1/Tada1
PANTHERiPTHR21277 PTHR21277, 1 hit
PfamiView protein in Pfam
PF12767 SAGA-Tad1, 2 hits

Sequencei

Sequence statusi: Complete.

Q99LM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATFVSELEA AKKNLSEALG DNVKQYWANL KLWFKQKISK EEFDLEAHRL
60 70 80 90 100
LTQDNVHSHN DFLLAILTRC QILVSTPEGA GSLPWTGGSA AKPGKPKGKK
110 120 130 140 150
KLSSVRQKFD HRFQPQNPLS GAQQFVAKEP QGDDDLKLCS HTMMLPTRGQ
160 170 180 190 200
LEGRMIVTAY EHGLDNVTEE AVSAVVYAVE NHLKDILTSV VSRRKAYRVR
210 220 230 240 250
DGHFKYAFGS NVTPQPYLKN SVVAYNNLVE GPPAFSAPCA NQSPASQPHP
260 270 280 290 300
DDAEQQAAFL LACSGDTLPA SLPPVNMYDL FEALQVHREV IPTHTVYALN
310 320 330
IERIIMKLWH PNHEELQQDK VHRQRLAAKE GLLLC
Length:335
Mass (Da):37,409
Last modified:June 1, 2001 - v1
Checksum:iF3CC5374DA55F918
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK151132 mRNA Translation: BAE30140.1
BC002307 mRNA Translation: AAH02307.1
BC027337 mRNA Translation: AAH27337.1
CCDSiCCDS15450.1
RefSeqiNP_084521.1, NM_030245.3
UniGeneiMm.100665
Mm.192094

Genome annotation databases

EnsembliENSMUST00000027846; ENSMUSP00000027846; ENSMUSG00000026563
GeneIDi27878
KEGGimmu:27878
UCSCiuc007dkm.2 mouse

Similar proteinsi

Entry informationi

Entry nameiTADA1_MOUSE
AccessioniPrimary (citable) accession number: Q99LM9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health