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Q99LL6

- Q99LL6_MOUSE

UniProt

Q99LL6 - Q99LL6_MOUSE

Protein
Submitted name:

Col1a1 protein

Gene

Col1a1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. extracellular matrix structural constituent Source: MGI
    2. protein binding Source: MGI

    GO - Biological processi

    1. blood vessel development Source: MGI
    2. bone trabecula formation Source: MGI
    3. cartilage development involved in endochondral bone morphogenesis Source: MGI
    4. cellular response to amino acid stimulus Source: MGI
    5. cellular response to retinoic acid Source: Ensembl
    6. cellular response to transforming growth factor beta stimulus Source: Ensembl
    7. collagen biosynthetic process Source: Ensembl
    8. collagen fibril organization Source: Ensembl
    9. embryonic skeletal system development Source: Ensembl
    10. endochondral ossification Source: MGI
    11. face morphogenesis Source: MGI
    12. intramembranous ossification Source: MGI
    13. negative regulation of cell-substrate adhesion Source: MGI
    14. positive regulation of canonical Wnt signaling pathway Source: Ensembl
    15. positive regulation of cell migration Source: Ensembl
    16. positive regulation of epithelial to mesenchymal transition Source: Ensembl
    17. positive regulation of transcription, DNA-templated Source: Ensembl
    18. protein heterotrimerization Source: MGI
    19. protein localization to nucleus Source: Ensembl
    20. protein transport Source: MGI
    21. response to cAMP Source: Ensembl
    22. response to corticosteroid Source: Ensembl
    23. response to estradiol Source: Ensembl
    24. response to hydrogen peroxide Source: Ensembl
    25. response to mechanical stimulus Source: Ensembl
    26. response to nutrient Source: Ensembl
    27. response to peptide hormone Source: Ensembl
    28. sensory perception of sound Source: Ensembl
    29. skeletal system development Source: MGI
    30. skeletal system morphogenesis Source: MGI
    31. skin development Source: MGI
    32. skin morphogenesis Source: Ensembl
    33. tooth mineralization Source: Ensembl
    34. visual perception Source: Ensembl
    35. wound healing Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Col1a1 proteinImported
    Gene namesi
    Name:Col1a1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:88467. Col1a1.

    Subcellular locationi

    GO - Cellular componenti

    1. collagen trimer Source: MGI
    2. collagen type I trimer Source: MGI
    3. cytoplasm Source: MGI
    4. extracellular matrix Source: MGI
    5. extracellular space Source: Ensembl
    6. proteinaceous extracellular matrix Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiQ99LL6.
    BgeeiQ99LL6.
    GenevestigatoriQ99LL6.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG103137.
    InParanoidiQ99LL6.

    Family and domain databases

    InterProiIPR008160. Collagen.
    IPR000885. Fib_collagen_C.
    [Graphical view]
    PfamiPF01410. COLFI. 1 hit.
    PF01391. Collagen. 5 hits.
    [Graphical view]
    ProDomiPD002078. Fib_collagen_C. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00038. COLFI. 1 hit.
    [Graphical view]
    PROSITEiPS51461. NC1_FIB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q99LL6-1 [UniParc]FASTAAdd to Basket

    « Hide

    FPGAAGRVGP PGPSGNAGPP GPPGPVGKEG GKGPRGETGP AGRPGEVGPP    50
    GPPGPAGEKG SPGADGPAGS PGTPGPQGIA GQRGVVGLPG QRGERGFPGL 100
    PGPSGEPGKQ GPSGSSGERG PPGPMGPPGL AGPPGESGRE GSPGAEGSPG 150
    RDGAPGAKGD RGETGPAGPP GAPGAPGAPG PVGPAGKNGD RGETGPAGPA 200
    GPIGPAGARG PAGPQGPRGD KGETGEQGDR GIKGHRGFSG LQGPPGSPGS 250
    PGEQGPSGAS GPAGPRGPPG SAGSPGKDGL NGLPGPIGPP GPRGRTGDSG 300
    PAGPPGPPGP PGPPGPPSGG YDFSFLPQPP QEKSQDGGRY YRADDANVVR 350
    DRDLEVDTTL KSLSQQIENI RSPEGSRKNP ARTCRDLKMC HSDWKSGEYW 400
    IDPNQGCNLD AIKVYCNMET GQTCVFPTQP SVPQKNWYIS PNPKEKKHVW 450
    FGESMTDGFP FEYGSEGSDP ADVAIQLTFL RLMSTEASQN ITYHCKNSVA 500
    YMDQQTGNLK KALLLQGSNE IELRGEGNSR FTYSTLVDGC TSHTGTWGKT 550
    VIEYKTTKTS RLPIIDVAPL DIGAPDQEFG LDIGPACFV 589
    Length:589
    Mass (Da):58,805
    Last modified:June 1, 2001 - v1
    Checksum:i81847495E5E05CEF
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC003198 mRNA. Translation: AAH03198.1.
    UniGeneiMm.277735.
    Mm.458212.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC003198 mRNA. Translation: AAH03198.1 .
    UniGenei Mm.277735.
    Mm.458212.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:88467. Col1a1.

    Phylogenomic databases

    HOVERGENi HBG103137.
    InParanoidi Q99LL6.

    Miscellaneous databases

    ChiTaRSi COL1A1. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q99LL6.
    Bgeei Q99LL6.
    Genevestigatori Q99LL6.

    Family and domain databases

    InterProi IPR008160. Collagen.
    IPR000885. Fib_collagen_C.
    [Graphical view ]
    Pfami PF01410. COLFI. 1 hit.
    PF01391. Collagen. 5 hits.
    [Graphical view ]
    ProDomi PD002078. Fib_collagen_C. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00038. COLFI. 1 hit.
    [Graphical view ]
    PROSITEi PS51461. NC1_FIB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: Mammary tumor. Metallothionien-TGF alpha model. 10 month old virgin mouse. Taken by biopsy.Imported.

    Entry informationi

    Entry nameiQ99LL6_MOUSE
    AccessioniPrimary (citable) accession number: Q99LL6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)