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Protein

Zinc finger protein 672

Gene

Znf672

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri15 – 3723C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri43 – 6523C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri71 – 9323C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri100 – 12324C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri129 – 15123C2H2-type 5; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri167 – 18923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri202 – 22423C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri230 – 25223C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri258 – 28023C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri286 – 30823C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri314 – 33623C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri342 – 36423C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri370 – 39223C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri398 – 42023C2H2-type 14PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 672
Gene namesi
Name:Znf672
Synonyms:Zfp672
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2442105. Zfp672.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 468468Zinc finger protein 672PRO_0000233992Add
BLAST

Proteomic databases

MaxQBiQ99LH4.
PaxDbiQ99LH4.
PeptideAtlasiQ99LH4.
PRIDEiQ99LH4.

PTM databases

PhosphoSiteiQ99LH4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000049755.
CleanExiMM_ZFP672.
ExpressionAtlasiQ99LH4. baseline and differential.
GenevisibleiQ99LH4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000060088.

Structurei

3D structure databases

ProteinModelPortaliQ99LH4.
SMRiQ99LH4. Positions 10-425.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 14 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri15 – 3723C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri43 – 6523C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri71 – 9323C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri100 – 12324C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri129 – 15123C2H2-type 5; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri167 – 18923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri202 – 22423C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri230 – 25223C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri258 – 28023C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri286 – 30823C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri314 – 33623C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri342 – 36423C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri370 – 39223C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri398 – 42023C2H2-type 14PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111556.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ99LH4.
OMAiHQGERPH.
OrthoDBiEOG091G02KC.
PhylomeDBiQ99LH4.
TreeFamiTF337999.

Family and domain databases

Gene3Di3.30.160.60. 12 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
PF13912. zf-C2H2_6. 2 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 14 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99LH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTAPGMATT QERPYSCSVC GKSFQYSAVL LRHERAHGGD KRFCCLECGE
60 70 80 90 100
RCARAADLRA HRWTHAGQTL YICSECGQSF SHSGLLDLHL GTHRRRSRTR
110 120 130 140 150
PCRLCGRRFP HVPALLLHRA RQHPPEKPHR CPLCARSFRQ SALPFHLARA
160 170 180 190 200
HPPEIITVTA PSPSTLYHCT QCPRAFHSSA GLRNHSRIHV VPSLSDPGTE
210 220 230 240 250
AHLCGICGKS FSKSSTLTRH LQRHSGEKPF KCPECGKGFL ESATLVRHQR
260 270 280 290 300
THTGEKPYAC SDCGRCFSES STLLRHQRSH QGERPHVCAT CGKGFGQRYD
310 320 330 340 350
LVVHQRSHTG ERPFPCPQCG RGFTDRSDLT KHLRTHTGEK PYHCELCGKR
360 370 380 390 400
FTCISNLNVH LRNHAGHKPH KCPECGKSFS VASKLALHRK THLGERTAEC
410 420 430 440 450
TECGKFFSHG RSLSQHQRSH RRARAAAMAA TTTTTVVTEV TIGPSLTLTG
460
PTEQEKSGLL VSPFQETC
Length:468
Mass (Da):52,154
Last modified:June 1, 2001 - v1
Checksum:i110623DEE3A39C1D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti306 – 3061R → H in BAC26575 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029711 mRNA. Translation: BAC26575.1.
AK035113 mRNA. Translation: BAC28948.1.
AK085166 mRNA. Translation: BAC39380.1.
AL845463 Genomic DNA. Translation: CAI25445.1.
BC003258 mRNA. Translation: AAH03258.1.
BC034706 mRNA. Translation: AAH34706.1.
CCDSiCCDS24727.1.
RefSeqiNP_001243445.1. NM_001256516.1.
NP_001243446.1. NM_001256517.1.
NP_001243447.1. NM_001256518.1.
NP_001243448.1. NM_001256519.1.
NP_001243449.1. NM_001256520.1.
NP_848876.2. NM_178761.5.
XP_006533583.1. XM_006533520.2.
XP_011247371.1. XM_011249069.1.
XP_011247372.1. XM_011249070.1.
UniGeneiMm.72124.

Genome annotation databases

EnsembliENSMUST00000057836; ENSMUSP00000060088; ENSMUSG00000049755.
ENSMUST00000064786; ENSMUSP00000070567; ENSMUSG00000049755.
ENSMUST00000108829; ENSMUSP00000104457; ENSMUSG00000049755.
GeneIDi319475.
KEGGimmu:319475.
UCSCiuc007jaz.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029711 mRNA. Translation: BAC26575.1.
AK035113 mRNA. Translation: BAC28948.1.
AK085166 mRNA. Translation: BAC39380.1.
AL845463 Genomic DNA. Translation: CAI25445.1.
BC003258 mRNA. Translation: AAH03258.1.
BC034706 mRNA. Translation: AAH34706.1.
CCDSiCCDS24727.1.
RefSeqiNP_001243445.1. NM_001256516.1.
NP_001243446.1. NM_001256517.1.
NP_001243447.1. NM_001256518.1.
NP_001243448.1. NM_001256519.1.
NP_001243449.1. NM_001256520.1.
NP_848876.2. NM_178761.5.
XP_006533583.1. XM_006533520.2.
XP_011247371.1. XM_011249069.1.
XP_011247372.1. XM_011249070.1.
UniGeneiMm.72124.

3D structure databases

ProteinModelPortaliQ99LH4.
SMRiQ99LH4. Positions 10-425.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000060088.

PTM databases

PhosphoSiteiQ99LH4.

Proteomic databases

MaxQBiQ99LH4.
PaxDbiQ99LH4.
PeptideAtlasiQ99LH4.
PRIDEiQ99LH4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000057836; ENSMUSP00000060088; ENSMUSG00000049755.
ENSMUST00000064786; ENSMUSP00000070567; ENSMUSG00000049755.
ENSMUST00000108829; ENSMUSP00000104457; ENSMUSG00000049755.
GeneIDi319475.
KEGGimmu:319475.
UCSCiuc007jaz.2. mouse.

Organism-specific databases

CTDi319475.
MGIiMGI:2442105. Zfp672.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111556.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ99LH4.
OMAiHQGERPH.
OrthoDBiEOG091G02KC.
PhylomeDBiQ99LH4.
TreeFamiTF337999.

Miscellaneous databases

PROiQ99LH4.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000049755.
CleanExiMM_ZFP672.
ExpressionAtlasiQ99LH4. baseline and differential.
GenevisibleiQ99LH4. MM.

Family and domain databases

Gene3Di3.30.160.60. 12 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
PF13912. zf-C2H2_6. 2 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 14 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZN672_MOUSE
AccessioniPrimary (citable) accession number: Q99LH4
Secondary accession number(s): Q8BIR7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.