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Q99L69

- Q99L69_MOUSE

UniProt

Q99L69 - Q99L69_MOUSE

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Protein
Submitted name: Branched chain ketoacid dehydrogenase E1, alpha polypeptide
Gene
Bckdha
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Source: InterPro

GO - Biological processi

  1. response to cAMP Source: Ensembl
  2. response to glucocorticoid Source: Ensembl
  3. response to nutrient Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Branched chain ketoacid dehydrogenase E1, alpha polypeptideImported
Gene namesi
Name:BckdhaImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107701. Bckdha.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ99L69.

Expressioni

Gene expression databases

ArrayExpressiQ99L69.
BgeeiQ99L69.
GenevestigatoriQ99L69.

Interactioni

Protein-protein interaction databases

MINTiMINT-1860593.

Structurei

3D structure databases

ProteinModelPortaliQ99L69.
SMRiQ99L69. Positions 48-442.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG002459.
InParanoidiQ99L69.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.

Sequencei

Sequence statusi: Complete.

Q99L69-1 [UniParc]FASTAAdd to Basket

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MSAAKIWRPS RGLRQAALLL LGRSGVRGLA RSHPSRQQQQ QFPSLDDKPQ    50
FPGASAEFVD KLEFIQPNVI SGIPIYRVMD RQGQIINPSE DPHLPQEEVL 100
KFYRSMTLLN TMDRILYESQ RQGRISFYMT NYGEEGTHVG SAAALERTDL 150
VFGQYREAGV LMYRDYPLEL FMSQCYGNVN DPGKGRQMPV HYGCKERHFV 200
TISSPLATQI PQAVGAAYAA KRANANRIVI CYFGEGAASE GDAHAGFNFA 250
ATLECPIIFF CRNNGYAIST PTSEQYRGDG IAARGPGYGI MSIRVDGNDV 300
FAVYNATKEA RRRAVAENQP FLIEAMTYRI GHHSTSDDSS AYRSVDEVNY 350
WDKQDHPISR LRQYLLNQGW WDEEQEKAWR KQSRKKVMEA FEQAERKLKP 400
NPSLLFSDVY QEMPAQLRRQ QESLARHLQT YGEHYPLDHF DK 442
Length:442
Mass (Da):50,359
Last modified:June 1, 2001 - v1
Checksum:i1BF54B9C99E858FA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC003787 mRNA. Translation: AAH03787.1.
UniGeneiMm.25848.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC003787 mRNA. Translation: AAH03787.1 .
UniGenei Mm.25848.

3D structure databases

ProteinModelPortali Q99L69.
SMRi Q99L69. Positions 48-442.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-1860593.

Proteomic databases

PRIDEi Q99L69.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:107701. Bckdha.

Phylogenomic databases

HOVERGENi HBG002459.
InParanoidi Q99L69.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q99L69.
Bgeei Q99L69.
Genevestigatori Q99L69.

Family and domain databases

Gene3Di 3.40.50.970. 1 hit.
InterProi IPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view ]
Pfami PF00676. E1_dh. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: Mammary tumor. Metallothionien-TGF alpha model. 10 month old virgin mouse. Taken by biopsy.Imported.

Entry informationi

Entry nameiQ99L69_MOUSE
AccessioniPrimary (citable) accession number: Q99L69
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: June 11, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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