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Q99L69

- Q99L69_MOUSE

UniProt

Q99L69 - Q99L69_MOUSE

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Protein
Submitted name:

Branched chain ketoacid dehydrogenase E1, alpha polypeptide

Gene

Bckdha

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. alpha-ketoacid dehydrogenase activity Source: Ensembl
  2. oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Source: InterPro

GO - Biological processi

  1. branched-chain amino acid catabolic process Source: Ensembl
  2. response to cAMP Source: Ensembl
  3. response to glucocorticoid Source: Ensembl
  4. response to nutrient Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Branched chain ketoacid dehydrogenase E1, alpha polypeptideImported
Gene namesi
Name:BckdhaImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107701. Bckdha.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial alpha-ketoglutarate dehydrogenase complex Source: Ensembl
  2. mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ99L69.

Expressioni

Gene expression databases

BgeeiQ99L69.
ExpressionAtlasiQ99L69. baseline and differential.
GenevestigatoriQ99L69.

Interactioni

Protein-protein interaction databases

MINTiMINT-1860593.

Structurei

3D structure databases

ProteinModelPortaliQ99L69.
SMRiQ99L69. Positions 48-442.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG002459.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.

Sequencei

Sequence statusi: Complete.

Q99L69-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAAKIWRPS RGLRQAALLL LGRSGVRGLA RSHPSRQQQQ QFPSLDDKPQ
60 70 80 90 100
FPGASAEFVD KLEFIQPNVI SGIPIYRVMD RQGQIINPSE DPHLPQEEVL
110 120 130 140 150
KFYRSMTLLN TMDRILYESQ RQGRISFYMT NYGEEGTHVG SAAALERTDL
160 170 180 190 200
VFGQYREAGV LMYRDYPLEL FMSQCYGNVN DPGKGRQMPV HYGCKERHFV
210 220 230 240 250
TISSPLATQI PQAVGAAYAA KRANANRIVI CYFGEGAASE GDAHAGFNFA
260 270 280 290 300
ATLECPIIFF CRNNGYAIST PTSEQYRGDG IAARGPGYGI MSIRVDGNDV
310 320 330 340 350
FAVYNATKEA RRRAVAENQP FLIEAMTYRI GHHSTSDDSS AYRSVDEVNY
360 370 380 390 400
WDKQDHPISR LRQYLLNQGW WDEEQEKAWR KQSRKKVMEA FEQAERKLKP
410 420 430 440
NPSLLFSDVY QEMPAQLRRQ QESLARHLQT YGEHYPLDHF DK
Length:442
Mass (Da):50,359
Last modified:June 1, 2001 - v1
Checksum:i1BF54B9C99E858FA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC003787 mRNA. Translation: AAH03787.1.
UniGeneiMm.25848.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC003787 mRNA. Translation: AAH03787.1 .
UniGenei Mm.25848.

3D structure databases

ProteinModelPortali Q99L69.
SMRi Q99L69. Positions 48-442.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-1860593.

Proteomic databases

PRIDEi Q99L69.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:107701. Bckdha.

Phylogenomic databases

HOVERGENi HBG002459.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q99L69.
ExpressionAtlasi Q99L69. baseline and differential.
Genevestigatori Q99L69.

Family and domain databases

Gene3Di 3.40.50.970. 1 hit.
InterProi IPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view ]
Pfami PF00676. E1_dh. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: Mammary tumor. Metallothionien-TGF alpha model. 10 month old virgin mouse. Taken by biopsy.Imported.

Entry informationi

Entry nameiQ99L69_MOUSE
AccessioniPrimary (citable) accession number: Q99L69
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)