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Q99KL7 (RAB28_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ras-related protein Rab-28
Gene names
Name:Rab28
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Cell membrane; Lipid-anchor; Cytoplasmic side Potential. Cytoplasmcytoskeletoncilium basal body. Note: Expressed in the basal body and ciliary rootlet of the photoreceptors By similarity.

Sequence similarities

Belongs to the small GTPase superfamily. Rab family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 218217Ras-related protein Rab-28
PRO_0000121228
Propeptide219 – 2213Removed in mature form By similarity
PRO_0000396722

Regions

Nucleotide binding19 – 279GTP By similarity
Nucleotide binding68 – 725GTP By similarity
Nucleotide binding129 – 1324GTP By similarity
Nucleotide binding159 – 1613GTP By similarity
Motif41 – 499Effector region By similarity

Amino acid modifications

Modified residue21N-acetylserine By similarity
Modified residue81Phosphoserine By similarity
Modified residue2181Cysteine methyl ester By similarity
Lipidation2181S-farnesyl cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q99KL7 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 5520BD9CC0F78FB9

FASTA22124,728
        10         20         30         40         50         60 
MSDSEEESQD RQLKIVVLGD GTSGKTSLAT CFAQETFGKQ YKQTIGLDFF LRRITLPGNL 

        70         80         90        100        110        120 
NVTLQVWDIG GQTIGGKMLD KYIYGAQGIL LVYDITNYQS FENLEDWYSV VKTVSEESET 

       130        140        150        160        170        180 
QPLVALVGNK IDLEHMRTVK ADKHLRFCQE NGFSSHFVSA KTGDSVFLCF QKVAAEILGI 

       190        200        210        220 
KLNKAEIEQS QRVVKADIVN YNQEPLSRTV NPPRSSMCAV Q 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC004580 mRNA. Translation: AAH04580.1.
CCDSCCDS19258.1.
RefSeqNP_081571.1. NM_027295.2.
UniGeneMm.41555.

3D structure databases

ProteinModelPortalQ99KL7.
SMRQ99KL7. Positions 8-184.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ99KL7.

Proteomic databases

PaxDbQ99KL7.
PRIDEQ99KL7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000031011; ENSMUSP00000031011; ENSMUSG00000029128.
GeneID100972.
KEGGmmu:100972.
UCSCuc008xha.1. mouse.

Organism-specific databases

CTD9364.
MGIMGI:1917285. Rab28.

Phylogenomic databases

eggNOGCOG1100.
GeneTreeENSGT00730000111076.
HOGENOMHOG000233968.
HOVERGENHBG101090.
InParanoidQ99KL7.
KOK07915.
OMACFQRIAA.
OrthoDBEOG74FF1S.
PhylomeDBQ99KL7.
TreeFamTF313852.

Gene expression databases

ArrayExpressQ99KL7.
BgeeQ99KL7.
CleanExMM_RAB28.
GenevestigatorQ99KL7.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamPF00071. Ras. 1 hit.
[Graphical view]
PRINTSPR00449. RASTRNSFRMNG.
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00231. small_GTP. 1 hit.
PROSITEPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSRAB28. mouse.
NextBio354708.
PROQ99KL7.
SOURCESearch...

Entry information

Entry nameRAB28_MOUSE
AccessionPrimary (citable) accession number: Q99KL7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot